| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P32829 | MRE11 | MR11_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Double-strand break repair protein MRE11. | 516 | e-145 | 271/532 (50%) | 353/532 (66%) | 11/532 (2%) |
| Q8NK73 | MHM11 | TrEMBL | Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) | Recombinational repair protein. | 508 | e-142 | 253/552 (45%) | 353/552 (63%) | 12/552 (2%) | |
| Q8J0S5 | MRE11 | TrEMBL | Emericella nidulans (Aspergillus nidulans) | Meiotic recombination protein. | 507 | e-142 | 253/534 (47%) | 356/534 (66%) | 9/534 (1%) | |
| Q09683 | RAD32 | RA32_SCHPO | SP | Schizosaccharomyces pombe (Fission yeast) | DNA repair protein rad32. | 479 | e-134 | 238/502 (47%) | 343/502 (68%) | 2/502 (0%) |
| Q9C291 | MUS-23 | MR11_NEUCR | SP | Neurospora crassa | Double-strand break repair protein mus-23 (Recombinational repair protein mus-23). | 479 | e-134 | 242/510 (47%) | 337/510 (66%) | 7/510 (1%) |
| Q9W6K1 | MRE11 | MR11_XENLA | SP | Xenopus laevis (African clawed frog) | Double-strand break repair protein MRE11. | 386 | e-106 | 203/513 (39%) | 311/513 (60%) | 11/513 (2%) |
| Q9JIM0 | MRE11A | MR11_RAT | SP | Rattus norvegicus (Rat) | Double-strand break repair protein MRE11A (MRE11 homolog 1). | 385 | e-105 | 201/512 (39%) | 311/512 (60%) | 10/512 (1%) |
| Q8BRV3 | TrEMBL | Mus musculus (Mouse) | Meiotic recombination 11 homolog A (Fragment). | 384 | e-105 | 204/512 (39%) | 313/512 (61%) | 10/512 (1%) | ||
| Q61216 | MRE11A | MR11_MOUSE | SP | Mus musculus (Mouse) | Double-strand break repair protein MRE11A (MRE11 homolog 1) (MmMRE11A). | 384 | e-105 | 204/512 (39%) | 313/512 (61%) | 10/512 (1%) |
| P49959 | MRE11A | MR11_HUMAN | SP | Homo sapiens (Human) | Double-strand break repair protein MRE11A (MRE11 homolog 1). | 382 | e-105 | 200/509 (39%) | 309/509 (60%) | 7/509 (1%) |
| Q9IAM7 | MRE11 | MR11_CHICK | SP | Gallus gallus (Chicken) | Double-strand break repair protein MRE11. | 368 | e-100 | 196/515 (38%) | 307/515 (59%) | 8/515 (1%) |
| Q9UVN9 | MRE11 | MR11_COPCI | SP | Coprinus cinereus (Inky cap fungus) | Double-strand break repair protein MRE11. | 358 | 1e-97 | 202/535 (37%) | 304/535 (56%) | 23/535 (4%) |
| Q9XGM2 | MRE11 | MR11_ARATH | SP | Arabidopsis thaliana (Mouse-ear cress) | Double-strand break repair protein MRE11. | 340 | 4e-92 | 189/517 (36%) | 296/517 (57%) | 10/517 (1%) |
| Q9XYZ4 | MRE11 | TrEMBL | Drosophila melanogaster (Fruit fly) | MRE11 protein. | 322 | 1e-86 | 179/432 (41%) | 259/432 (59%) | 18/432 (4%) | |
| Q9GZJ8 | MRE11 | TrEMBL | Bombyx mori (Silk moth) | Mre11. | 315 | 1e-84 | 185/502 (36%) | 294/502 (58%) | 7/502 (1%) | |
| Q23255 | MRE-11 | MR11_CAEEL | SP | Caenorhabditis elegans | Double-strand break repair protein mre-11. | 301 | 2e-80 | 184/461 (39%) | 259/461 (56%) | 13/461 (2%) |
| Q8WPP1 | MRE11 | TrEMBL | Trypanosoma brucei | Mre11 protein. | 249 | 9e-65 | 158/494 (31%) | 263/494 (53%) | 13/494 (2%) | |
| Q8T8P1 | MRE11 | TrEMBL | Trypanosoma brucei brucei | DNA repair protein Mre11. | 249 | 9e-65 | 158/494 (31%) | 263/494 (53%) | 13/494 (2%) | |
| Q8SRV0 | ECU05_1280 | TrEMBL | Encephalitozoon cuniculi | Double-strand break DNA repair protein (RAD32 homolog). | 231 | 3e-59 | 155/504 (30%) | 266/504 (52%) | 9/504 (1%) | |
| Q9BS79 | TrEMBL | Homo sapiens (Human) | Hypothetical protein (MRE11 meiotic recombination 11 homolog A) (S. cerevisiae). | 207 | 3e-52 | 99/195 (50%) | 141/195 (72%) | 3/195 (1%) | ||
| Q86C23 | TrEMBL | Entamoeba histolytica | Mre11. | 182 | 1e-44 | 141/502 (28%) | 231/502 (46%) | 21/502 (4%) | ||
| Q8I263 | PFA0390W | TrEMBL | Plasmodium falciparum (isolate 3D7) | DNA repair exonuclease, putative. | 141 | 3e-32 | 84/237 (35%) | 134/237 (56%) | 5/237 (2%) | |
| Q86C19 | TrEMBL | Giardia lamblia (Giardia intestinalis) | Mre11. | 60.8 | 6e-08 | 96/444 (21%) | 174/444 (39%) | 45/444 (10%) | ||
| Q8TRL2 | MA1163 | TrEMBL | Methanosarcina acetivorans | DNA repair exonuclease. | 58.2 | 4e-07 | 73/287 (25%) | 111/287 (38%) | 5/287 (1%) | |
| Q8NKQ0 | MRE11 | TrEMBL | Sulfolobus acidocaldarius | Mre11 protein. | 55.5 | 3e-06 | 94/460 (20%) | 177/460 (38%) | 23/460 (5%) | |
| Q8PUY5 | MM2193 | TrEMBL | Methanosarcina mazei (Methanosarcina frisia) | DNA repair protein. | 55.5 | 3e-06 | 71/287 (24%) | 109/287 (37%) | 5/287 (1%) | |
| O29231 | AF1031 | TrEMBL | Archaeoglobus fulgidus | DNA repair protein RAD32 (RAD32). | 53.5 | 1e-05 | 44/157 (28%) | 70/157 (44%) | 5/157 (3%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Mre11_DNA_bind Mre11 DNA-binding presumed domain 219.5 5.1e-62 1 Metallophos Calcineurin-like phosphoesterase 67.2 3.4e-16 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- Metallophos 1/1 14 249 .. 1 124 [] 67.2 3.4e-16 Mre11_DNA_bind 1/1 250 480 .. 1 241 [] 219.5 5.1e-62
CDS Sequence
ATGCCATTGG TAGAACGTAT AGAACCAGGA CCTGACACAA TTAGGGTTCT ACTAACTACT GACAATCATG TAGGAGCATT TGAAAACGAT CCAATTAGAG GTGATGATGC ATGGAAAACA TTTGATGAAA TCACCACCAT TGCCAAAGAT AAAGATGTTG ATATGATAAT TCAAGGAGGT GATTTATTTC ATATTAACAA ACCAACGAAA AAATCCATGT ATCATGTTAT GAAATCACTT CGATCCAATT GTATGGGAGA TCGTCCTTGT GAATTAGAAT TATTGAGTGA TCCGGCTCAA TCATTAAATA ATGGATTTGA TGAAATTAAT TATGAAGATC CAAATTTAAA TATATCTATC CCGGTGTTTG CCATTAGTGG GAATCATGAT GATGCCACTG GTGAATCATT ATTACTGGCA TTGGATGTAT TAGCCGTCAC GGGATTAATT AATAATTTTG GTAAAGTGAA AAACACTGAG GCAATAACTG TTTCACCAAT ATTATTACAA AAGGGACAAA CAAAATTGGC ATTGTATGGG ATGTCAAATG TAAGAGATGA AAGATTGCAT CGATTATTTC GAGATGGTGG AGTCAAATTT CAACGTCCAA ATATACAAAC TGAAGATTGG TTCAATTTAT TTGTTATTCA TCAAAATCAT GCTGCTCATA CTTATACTTC CAGTATACCA GAATCATTTT TACCAAATTT CCTTGATTTT ATATTATGGG GTCATGAACA TGAATGTATT CCTTATCCAG TGCATAATCC AGAAACCACA TTTGATGTAT TACAAGCAGG TTCATCGGTG GCTACTTCAT TAGCTGAAGG TGAAGTTGCC GATAAAAAAA TATTTATTTT AAATATAAAG GGTAAAGATT ATTCTATTGA ACCAGTTGAA TTGAAAACAG TACGACCATT TGTATTAAGA GAAATTATAT TACTGAAAAC TGATCTTATT CCTGGTGCTG CTTCTAAAGC TGATGTTATT GCATATTTAA CTGATGAAGT GGAAAAATCC ATTGAAAGAG CAAATAAACA ATTTAGTAGC CAAAATATTC TGAATTCTAA TCGAGCAATC ACTAACCTGA GCAACAATGC AACTGCAGAT CCCATTGAAA AGCCATTACC ATTGATTAGA TTGCGAGTCG AGTATAGTGG TGGATATGAA ATTGAAAATG TGACGAGATT TTCCAATAGA TTTGTTGGCA AAATTGCTAA TGTTAATGAT GTGGTTCAAT TTTATAAGAA AAAGACACCA ACAAAAAGTG ATAATAAATT AACTCGGAAA ACTAAATATG ACGTTGATTT AATTGAAGAA AATTTACATC ATAAAAAAAC CACTGAATTG GAACTTCAAG ATATTATTCG GGATTTCTTA CAACAAACTC AATTATCATT AGTTCCTGAA ACTGAAATGA ATCATGCCGT TAAAAAATTT GTTGAAAATG ATGATAAACA AGCTTTAAAT CAATTTATTA ATCAAGAAAT TAAACGAGAA ACCAAAATGT TATTAGATAT TGATATTGAT GAAAATGAAT TTCATGGAGC TGATGAAAAA CATGCTAAAA CGGCGTTTAA ACATGTATTA CTGCAATTGA AAAATATCAA TGGGCCTATT AATATAGATT ATGAACCTGA AATTGAACCA ACTAACAACA ACACCAACAA AAAGTCTGCT ACTACAAAGA AAAGAACCCC TAAGAAAAAT ACCACCATCC CTAAAAAGAT AACAACAACA GCCACCAAAA AACCTAAAAT TGATGATATA ATTATAAGTT CAGATGATAG TAATGATTAC GGCAATGACG ACGATGACGA TAAAGAAGAA GAAGAAGAAG AAAATGAACA TGACTCTGGT CTTCGTTTGT TTGTGACTGA TACACCTGAC ACCAATAGTA CACGTCGATC TAAAAGTAAT CGATCCAAAA GACCAACTAG TTATGTTGAA GATGAGTCAG GTATACTTAG TGATGAAGAT GATTATGTTC CACCCAGTAA AAGTAAAGGA ATATTTTCCA GAAGCTTTAA TAACAGGAAA AGAAAATAA
AA Sequence
MPLVERIEPG PDTIRVLLTT DNHVGAFEND PIRGDDAWKT FDEITTIAKD KDVDMIIQGG DLFHINKPTK KSMYHVMKSL RSNCMGDRPC ELELLSDPAQ SLNNGFDEIN YEDPNLNISI PVFAISGNHD DATGESLLLA LDVLAVTGLI NNFGKVKNTE AITVSPILLQ KGQTKLALYG MSNVRDERLH RLFRDGGVKF QRPNIQTEDW FNLFVIHQNH AAHTYTSSIP ESFLPNFLDF ILWGHEHECI PYPVHNPETT FDVLQAGSSV ATSLAEGEVA DKKIFILNIK GKDYSIEPVE LKTVRPFVLR EIILLKTDLI PGAASKADVI AYLTDEVEKS IERANKQFSS QNILNSNRAI TNLSNNATAD PIEKPLPLIR LRVEYSGGYE IENVTRFSNR FVGKIANVND VVQFYKKKTP TKSDNKLTRK TKYDVDLIEE NLHHKKTTEL ELQDIIRDFL QQTQLSLVPE TEMNHAVKKF VENDDKQALN QFINQEIKRE TKMLLDIDID ENEFHGADEK HAKTAFKHVL LQLKNINGPI NIDYEPEIEP TNNNTNKKSA TTKKRTPKKN TTIPKKITTT ATKKPKIDDI IISSDDSNDY GNDDDDDKEE EEEENEHDSG LRLFVTDTPD TNSTRRSKSN RSKRPTSYVE DESGILSDED DYVPPSKSKG IFSRSFNNRK RK*