| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P47161 | YJR126C | YJ96_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Hypothetical 92.0 kDa protein in RPS5-ZMS1 intergenic region. | 385 | e-105 | 246/713 (34%) | 370/713 (51%) | 8/713 (1%) |
| P70627 | FOLH1 | FOH1_RAT | SP | Rattus norvegicus (Rat) | Glutamate carboxypeptidase II (EC 3.4.17.21) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate-specific membrane antigen homolog). | 305 | 2e-81 | 228/725 (31%) | 349/725 (48%) | 30/725 (4%) |
| O35409 | FOLH1 | FOH1_MOUSE | SP | Mus musculus (Mouse) | Glutamate carboxypeptidase II (EC 3.4.17.21) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate-specific membrane antigen homolog). | 298 | 2e-79 | 228/725 (31%) | 347/725 (47%) | 30/725 (4%) |
| O77564 | FOLH1 | FOH1_PIG | SP | Sus scrofa (Pig) | Glutamate carboxypeptidase II (EC 3.4.17.21) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate-specific membrane antigen homolog). | 290 | 4e-77 | 225/742 (30%) | 354/742 (47%) | 38/742 (5%) |
| Q80YF8 | TrEMBL | Mus musculus (Mouse) | NAAG-peptidase II. | 285 | 2e-75 | 190/556 (34%) | 297/556 (53%) | 30/556 (5%) | ||
| Q9Y3Q0 | NAALAD2 | NLD2_HUMAN | SP | Homo sapiens (Human) | N-acetylated-alpha-linked acidic dipeptidase II (EC 3.4.17.21) (NAALADase II). | 279 | 1e-73 | 193/543 (35%) | 287/543 (52%) | 31/543 (5%) |
| Q04609 | FOLH1 | FOH1_HUMAN | SP | Homo sapiens (Human) | Glutamate carboxypeptidase II (EC 3.4.17.21) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate-specific membrane antigen) (PSMA) (PSM). | 278 | 3e-73 | 190/548 (34%) | 292/548 (53%) | 32/548 (5%) |
| Q8TAY3 | TrEMBL | Homo sapiens (Human) | Similar to folate hydrolase (Prostate-specific membrane antigen) 1. | 278 | 3e-73 | 190/548 (34%) | 292/548 (53%) | 32/548 (5%) | ||
| Q7ZUD9 | TrEMBL | Brachydanio rerio (Zebrafish) (Danio rerio) | Similar to folate hydrolase (Prostate-specific membrane antigen) 1. | 259 | 8e-68 | 191/548 (34%) | 280/548 (51%) | 33/548 (6%) | ||
| O54697 | NAALADL | NLDL_RAT | SP | Rattus norvegicus (Rat) | N-acetylated-alpha-linked acidic dipeptidase like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100). | 248 | 3e-64 | 189/595 (31%) | 300/595 (50%) | 45/595 (7%) |
| Q9UQQ1 | NAALADL | NLDL_HUMAN | SP | Homo sapiens (Human) | N-acetylated-alpha-linked acidic dipeptidase like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100). | 241 | 2e-62 | 182/590 (30%) | 298/590 (50%) | 37/590 (6%) |
| Q852M4 | OSJNBA0087O09.17 | TrEMBL | Oryza sativa (japonica cultivar-group) | Putative glutamate carboxypeptidase. | 238 | 3e-61 | 189/569 (33%) | 277/569 (48%) | 39/569 (6%) | |
| P91406 | R57.1 | GCP2_CAEEL | SP | Caenorhabditis elegans | Glutamate carboxypeptidase II homolog (EC 3.4.17.21). | 221 | 4e-56 | 175/608 (28%) | 293/608 (48%) | 42/608 (6%) |
| Q8PGK5 | XAC3611 | TrEMBL | Xanthomonas axonopodis (pv. citri) | Peptidase. | 220 | 7e-56 | 173/553 (31%) | 263/553 (47%) | 28/553 (5%) | |
| Q9M1S8 | AMP1 | GCP2_ARATH | SP | Arabidopsis thaliana (Mouse-ear cress) | Probable glutamate carboxypeptidase II (EC 3.4.17.21). | 220 | 5e-56 | 177/574 (30%) | 280/574 (48%) | 21/574 (3%) |
| Q93332 | C35C5.2 | TrEMBL | Caenorhabditis elegans | C35C5.2 protein. | 193 | 9e-48 | 166/575 (28%) | 270/575 (46%) | 61/575 (10%) | |
| Q94JH4 | P0638D12.15 | TrEMBL | Oryza sativa (Rice) | Peptidase-like protein. | 188 | 3e-46 | 133/374 (35%) | 193/374 (51%) | 9/374 (2%) | |
| Q94JH3 | P0638D12.16 | TrEMBL | Oryza sativa (Rice) | Peptidase-like protein. | 186 | 1e-45 | 128/377 (33%) | 194/377 (51%) | 12/377 (3%) | |
| Q9UP52 | TFR2 | TFR2_HUMAN | SP | Homo sapiens (Human) | Transferrin receptor protein 2 (TfR2). | 181 | 3e-44 | 129/395 (32%) | 198/395 (50%) | 11/395 (2%) |
| Q9JKX3 | TFR2 | TFR2_MOUSE | SP | Mus musculus (Mouse) | Transferrin receptor protein 2 (TfR2). | 179 | 1e-43 | 138/446 (30%) | 211/446 (47%) | 10/446 (2%) |
| O43023 | SPBC354.09C | YGV9_SCHPO | SP | Schizosaccharomyces pombe (Fission yeast) | Putative zinc metallopeptidase C354.09c in chromosome II. | 171 | 5e-41 | 179/713 (25%) | 304/713 (42%) | 22/713 (3%) |
| Q9HBA9 | PSMAL/GCP | TrEMBL | Homo sapiens (Human) | Prostate-specific membrane antigen-like protein. | 160 | 5e-38 | 122/444 (27%) | 202/444 (45%) | 18/444 (4%) | |
| Q86FL5 | R57.1 | TrEMBL | Caenorhabditis elegans | Hypothetical protein R57.1. | 149 | 2e-34 | 125/407 (30%) | 196/407 (48%) | 23/407 (5%) | |
| Q90997 | TFRC | TFR1_CHICK | SP | Gallus gallus (Chicken) | Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr). | 147 | 6e-34 | 136/481 (28%) | 226/481 (46%) | 13/481 (2%) |
| Q9GLD3 | TFRC | TFR1_CANFA | SP | Canis familiaris (Dog) | Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr). | 136 | 1e-30 | 133/465 (28%) | 213/465 (45%) | 17/465 (3%) |
| Q8IUX3 | TrEMBL | Homo sapiens (Human) | Similar to N-acetylated alpha-linked acidic dipeptidase 2. | 133 | 8e-30 | 91/238 (38%) | 132/238 (55%) | 8/238 (3%) | ||
| Q9XH28 | F10A2.10 | TrEMBL | Arabidopsis thaliana (Mouse-ear cress) | F10A2.10 protein (Putative peptidase). | 132 | 2e-29 | 106/305 (34%) | 154/305 (50%) | 15/305 (4%) | |
| Q8LQ62 | P0439E07.18 | TrEMBL | Oryza sativa (japonica cultivar-group) | Putative peptidase-like protein. | 130 | 7e-29 | 104/294 (35%) | 145/294 (49%) | 8/294 (2%) | |
| Q99376 | TFRC | TFR1_RAT | SP | Rattus norvegicus (Rat) | Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (Fragment). | 129 | 2e-28 | 110/381 (28%) | 174/381 (45%) | 10/381 (2%) |
| Q9MYZ3 | TFRC | TFR1_FELCA | SP | Felis silvestris catus (Cat) | Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr). | 129 | 2e-28 | 107/374 (28%) | 173/374 (46%) | 10/374 (2%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Peptidase_M28 Peptidase family M28 190.9 2e-53 1 PA PA domain 57.1 3.9e-13 1 TFR_dimer Transferrin receptor-like dimerisation -3.3 0.062 1 Peptidase_M20 Peptidase family M20/M25/M40 -100.9 8.8 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PA 1/1 152 255 .. 1 111 [] 57.1 3.9e-13 Peptidase_M28 1/1 329 565 .. 1 280 [] 190.9 2e-53 Peptidase_M20 1/1 65 653 .. 1 513 [] -100.9 8.8 TFR_dimer 1/1 638 765 .. 1 153 [] -3.3 0.062
CDS Sequence
ATGTTGTACG AGAAAAGAGT ATTACCTCCT AAAAGGAGCT ATCAGAGGAA CCCAATTGTC TGGGCATTCT TTGTCTTGGC TATTCTTACC ATTTATAAAT TACCCTTAAC TTTGTTTCCT CAAGAACAAG ATGTTATCGA CCCTAAAGCT GTTATTCTCA ATGCCCTTGA AACCAATTTA GCTGGTAATT GGTCACGCAA GTACACTGCT GAGCCACATT TGGCAGGCAC GAACTACGGT TTGGTTGCAT GGACTGAACT GAAATTTAAG GAGTACGGGC TTAAGACTCA AGTTGACACT TATGATATTT ATGTTAGTTA TCCAAAAGAC CATGACTTGA AGTTGATTAA TAAAAAGGGC CACGTCGAGT ACCAACCATC ATTAAAGGAA GATGTCATTG ATGAAGACTC AACTACACAT GGAAATGACA CAGTCCCCAC ATTTTTGGGA TATGCTGCCA ATGGGAATGT AACTGCTGAA TACGTTTTTG TCAACTACGG GACTAAAGAC GATTTCGATT TTTTAAAGGA GCAAAAAGTT AATGTTACTG GTAAAATCGC CATTGCTCGT TATGGCAAAA TTTTCCGTGG CTTAAAAGTC AAATTTGCTC AAGAACATGG TGCTGTTGGT GTTTTGATAT ATTCCGACCC AGGAGATGAC CAAGGAATCA CACCTGCCAA CGGCTATAAA CAATATCCTC ATGGTCCTGC ACGTCAAGAA AGTTCTGTTC AAAGAGGGTC TGTACAATTC TTGTCACAAA TCCCTGGAGA CCCTACTACC CCAGGTTACC CTTCCAAGGG AGACGTGGAG CGCAAAGACC CTCATGAAAG TATTGGTAGA ATTCCTGCTT TGCCGATTTC GTATCGCGAA GTCAAACCCA TATTGGCCAA ACTCAACGGA TTTGGTATAC AACCAGACCT GTTTGCCGGC GAGTTAGAAG GATTTGACTA TTTTACTGGA CCAAACCCAA AATACACGTT AAACTTGTAC AATGACCAAA TTTACAATAT TACACCATTA TGGAATGTTT ATGGAGAAAT TGAAGGTCAG AACAAAGACG AGGTAATTAT AATTGGTAAT CACAGAGACG CATGGATCAA AGGAGGCGCA TCGGACCCCA ATAGTGGCTC TGCTGCTTTG TTGGAGATTG CTCGTGCTTT AAACGAATTA AAACAGCAAA ATTATAAATT CAAACGTACA ATAATTTTGC ACAGTTATGA TGGCGAAGAG TATGGACTTT TGGGTTCCAC CGAGCAAGGG GAATACTATG CTGAAAAGTA TCAGCGCAAT GTTGTGGCAT ACTTGAACTT GGACGACGCT GTTTCAGGAA AACATTTCAA GTTGAGTGCA TCTCCAGTAT TAGATGAGGT ATTGTTAGCT GTTGCCAAAG AATTAGAATA CCCAGAAAAG GGGGCCGCTA GTTTGTATGA CCACTGGTTG GCCAATGGTG GTAGAATCAA ACCTCTTGGG TCTGGGTCCG ATTATACAGT TTACCTTGAC CATCTCGGTA TTCCCTCAGT GGACTTGGGT TTTGCTGGTG GGAAAGGTGA CCCAGTATAT CATTATCATT CCAACTACGA CTCTTACCAC TGGATGAAGA AGTTTGGCGA CGAGGGGTTT GTATTCCACA ATTTGTGTGC CAAATATGTA CTGTTGCTTG CATTACAGTT GTCAGAGAGA GAAGTCATTG ATTTCAGACT TTCCAGCTAC TCGAAAAAGT TGCAAGAGTA TTACAACTCC ACTGTTTCAA CCATTCCCAA GTCGTGGTTG AACAAAACGG TAAAATCCTC ACACACAGAC TGGGAAGAAT ATAATTTTAT CAATAAAGCC ACCAATGGTT ATTATACAGA CGAGATTCCA GAGGGCAAAC AATGCAGAAT GATGAGACGT ATCCATCACC ACAAACACAA AACCACTTTG CAAGAACTAG TAGCTGCAAC TTTTGACAAA TTGGAGAAAT TTGATAATGT CACCCAATCC TTGGACCTCA CCTCCTTCAA ATTGCAAGCA CTTTATGATG ATTACGACAA TTTACCATTG TGGGAGAGAA TCAAATTACA TTTCCGTATC AGACACCACA ATAAATTGTT ACAGTATTTT GAAAGAAACT TTCTTCATCA AAAGGGATTA CACAACAGAT TCTGGTTCAG ACACATTGTT TATGCCAGCG GAAGATACAC TGGGTATGCG GGACAAACAT TGCCGGGATT AAATGAAGCT ATTGAAGATG GTGATTTCGA TAGATTTGTG CATTGGGTCA ATATCTTTGC CAGAACTTTG AAGAGAATCA ATAGACATTC ATAA
AA Sequence
MLYEKRVLPP KRSYQRNPIV WAFFVLAILT IYKLPLTLFP QEQDVIDPKA VILNALETNL AGNWSRKYTA EPHLAGTNYG LVAWTELKFK EYGLKTQVDT YDIYVSYPKD HDLKLINKKG HVEYQPSLKE DVIDEDSTTH GNDTVPTFLG YAANGNVTAE YVFVNYGTKD DFDFLKEQKV NVTGKIAIAR YGKIFRGLKV KFAQEHGAVG VLIYSDPGDD QGITPANGYK QYPHGPARQE SSVQRGSVQF LSQIPGDPTT PGYPSKGDVE RKDPHESIGR IPALPISYRE VKPILAKLNG FGIQPDLFAG ELEGFDYFTG PNPKYTLNLY NDQIYNITPL WNVYGEIEGQ NKDEVIIIGN HRDAWIKGGA SDPNSGSAAL LEIARALNEL KQQNYKFKRT IILHSYDGEE YGLLGSTEQG EYYAEKYQRN VVAYLNLDDA VSGKHFKLSA SPVLDEVLLA VAKELEYPEK GAASLYDHWL ANGGRIKPLG SGSDYTVYLD HLGIPSVDLG FAGGKGDPVY HYHSNYDSYH WMKKFGDEGF VFHNLCAKYV LLLALQLSER EVIDFRLSSY SKKLQEYYNS TVSTIPKSWL NKTVKSSHTD WEEYNFINKA TNGYYTDEIP EGKQCRMMRR IHHHKHKTTL QELVAATFDK LEKFDNVTQS LDLTSFKLQA LYDDYDNLPL WERIKLHFRI RHHNKLLQYF ERNFLHQKGL HNRFWFRHIV YASGRYTGYA GQTLPGLNEA IEDGDFDRFV HWVNIFARTL KRINRHS*