| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| Q873D6 | B17B1.060 | TrEMBL | Neurospora crassa | Related to a retinal short-chain dehydrogenase/reductase. | 182 | 7e-45 | 106/239 (44%) | 150/239 (62%) | 4/239 (1%) | |
| Q07530 | YDL114W | TrEMBL | Saccharomyces cerevisiae (Baker's yeast) | Chromosome IV reading frame ORF YDL114W. | 165 | 9e-40 | 82/229 (35%) | 140/229 (61%) | 3/229 (1%) | |
| Q8CJ68 | RDH10 | TrEMBL | Mus musculus (Mouse) | Retinol dehydrogenase 10. | 136 | 5e-31 | 83/213 (38%) | 120/213 (56%) | 3/213 (1%) | |
| Q8VCH7 | RDH10 | TrEMBL | Mus musculus (Mouse) | Hypothetical protein (Fragment). | 136 | 5e-31 | 83/213 (38%) | 120/213 (56%) | 3/213 (1%) | |
| Q8IZV5 | RDH10 | TrEMBL | Homo sapiens (Human) | Retinol dehydrogenase 10. | 136 | 4e-31 | 84/213 (39%) | 120/213 (56%) | 3/213 (1%) | |
| Q8HZT6 | RDH10 | TrEMBL | Bos taurus (Bovine) | Retinol dehydrogenase 10. | 136 | 4e-31 | 84/213 (39%) | 120/213 (56%) | 3/213 (1%) | |
| Q80ZF7 | TrEMBL | Rattus norvegicus (Rat) | Retinol dehydrogenase 10. | 136 | 4e-31 | 84/213 (39%) | 120/213 (56%) | 3/213 (1%) | ||
| O02294 | T02E1.5 | TrEMBL | Caenorhabditis elegans | T02E1.5 protein. | 130 | 3e-29 | 81/228 (35%) | 123/228 (53%) | 1/228 (0%) | |
| Q06417 | YLR426W | TrEMBL | Saccharomyces cerevisiae (Baker's yeast) | Similar to 3-oxoacyl-[acyl-carrier protein] reductase. | 126 | 5e-28 | 71/209 (33%) | 116/209 (55%) | 2/209 (0%) | |
| O18030 | T05F1.10 | TrEMBL | Caenorhabditis elegans | T05F1.10 protein. | 126 | 4e-28 | 81/244 (33%) | 130/244 (53%) | 8/244 (3%) | |
| Q22392 | T11F9.11 | TrEMBL | Caenorhabditis elegans | T11F9.11 protein. | 122 | 7e-27 | 83/241 (34%) | 126/241 (52%) | 7/241 (2%) | |
| Q9VR28 | CG15629 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG15629 protein. | 119 | 6e-26 | 66/166 (39%) | 95/166 (57%) | ||
| Q8N3Y7 | TrEMBL | Homo sapiens (Human) | Retinal short chain dehydrogenase reductase (Fragment). | 116 | 5e-25 | 66/166 (39%) | 91/166 (54%) | |||
| Q8TDV9 | RDH-E2 | TrEMBL | Homo sapiens (Human) | Retinal short chain dehydrogenase reductase. | 116 | 4e-25 | 67/166 (40%) | 91/166 (54%) | ||
| Q8SYX3 | CG9265 | TrEMBL | Drosophila melanogaster (Fruit fly) | RE29926p. | 114 | 1e-24 | 70/196 (35%) | 113/196 (57%) | 2/196 (1%) | |
| Q9VIG6 | CG9265 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG9265 protein. | 113 | 3e-24 | 70/196 (35%) | 112/196 (57%) | 2/196 (1%) | |
| Q8NBQ5 | TrEMBL | Homo sapiens (Human) | Hypothetical protein NT2RP1000544. | 113 | 3e-24 | 62/163 (38%) | 96/163 (58%) | |||
| Q9UKU4 | TrEMBL | Homo sapiens (Human) | Retinal short-chain dehydrogenase/reductase retSDR2 (CTCL tumor antigen Li9-4) (Similar to hydroxysteroid 17-beta dehydrogenase 11). | 113 | 3e-24 | 62/163 (38%) | 96/163 (58%) | |||
| O42949 | SPBC21H7.08 | TrEMBL | Schizosaccharomyces pombe (Fission yeast) | Putative dehydrogenase C21H7.08 precursor (EC 1.-.-.-). | 109 | 6e-23 | 69/234 (29%) | 117/234 (50%) | ||
| Q9EQ06 | HSD17B11 | TrEMBL | Mus musculus (Mouse) | Alcohol dehydrogenase Pan1b (Retinal short-chain dehydrogenase/reductase SDR2) (Hydroxysteroid (17-beta) dehydrogenase 11). | 108 | 1e-22 | 59/163 (36%) | 92/163 (56%) | ||
| Q96HF6 | TrEMBL | Homo sapiens (Human) | Similar to retinal short-chain dehydrogenase/reductase retSDR2. | 108 | 1e-22 | 68/197 (34%) | 111/197 (56%) | 1/197 (0%) | ||
| Q86W23 | TrEMBL | Homo sapiens (Human) | 17-beta hydroxysteroid dehydrogenase. | 107 | 2e-22 | 63/166 (37%) | 91/166 (54%) | |||
| Q8VCR2 | TrEMBL | Mus musculus (Mouse) | Similar to hydroxysteroid 17-beta dehydrogenase 11. | 106 | 4e-22 | 66/179 (36%) | 98/179 (54%) | |||
| Q9BUC8 | TrEMBL | Homo sapiens (Human) | Short-chain dehydrogenase/reductase 1. | 105 | 1e-21 | 76/247 (30%) | 121/247 (48%) | 8/247 (3%) | ||
| O75911 | RETSDR1 | TrEMBL | Homo sapiens (Human) | Retinal short-chain dehydrogenase/reductase RETSDR1 (EC 1.-.-.-). | 105 | 1e-21 | 76/247 (30%) | 121/247 (48%) | 8/247 (3%) | |
| O77769 | RETSDR1 | TrEMBL | Bos taurus (Bovine) | Retinal short-chain dehydrogenase/reductase RETSDR1 (EC 1.-.-.-). | 105 | 1e-21 | 68/206 (33%) | 105/206 (50%) | 7/206 (3%) | |
| Q8CIU2 | TrEMBL | Mus musculus (Mouse) | Alcohol dehydrogenase PAN1B-like protein (Fragment). | 105 | 7e-22 | 70/201 (34%) | 108/201 (53%) | 1/201 (0%) | ||
| O88876 | RSDR1 | TrEMBL | Mus musculus (Mouse) | Retinal short-chain dehydrogenase/reductase RETSDR1 (EC 1.-.-.-). | 102 | 6e-21 | 74/247 (29%) | 121/247 (48%) | 8/247 (3%) | |
| Q91WR0 | RSDR1 | TrEMBL | Mus musculus (Mouse) | Retinal short-chain dehydrogenase/reductase 1. | 102 | 6e-21 | 74/247 (29%) | 121/247 (48%) | 8/247 (3%) | |
| Q91XC3 | RSDR1 | TrEMBL | Mus musculus (Mouse) | Similar to retinal short-chain dehydrogenase/reductase 1. | 101 | 2e-20 | 73/247 (29%) | 120/247 (48%) | 8/247 (3%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- adh_short short chain dehydrogenase 145.4 1e-39 1 TrkA-N TrkA-N domain -37.0 8.8 1 Epimerase NAD dependent epimerase/dehydratase family -206.7 6.7 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- TrkA-N 1/1 36 150 .. 1 122 [] -37.0 8.8 adh_short 1/1 34 289 .. 1 271 [] 145.4 1e-39 Epimerase 1/1 38 307 .. 1 358 [] -206.7 6.7
CDS Sequence
ATGTTTGTTA TTCTCTCTCT AATCATCGAC TTGATCTATT GGTTAAATAA ACAATTTAGA TATATATCTG ATCTAATCAT TGGTAATGTT TTTGATCCGA GGTTTGATAT TGTTTTAGTG ACTGGTGGTG TAACAGGGTT GGGACGAGAA CTTGTGCTGC AAATTATTTC CAAAGGTGCA CAGGTTGTCG TATTGGATAT ATTAGAACCT TTAGAAGAAG ATTTAAACAC AGTTGGATTG ACACATTACA AATGTGATGT TAGTGATCCT CAGGATGTTT TAAGAACACA AAAGCTAGTG AGAAAAGAAA TTGGGGTAGT AACCGTACTA ATAAACAATG CCGGTATTGC AACGGGGAAA CCGGTATTGG ATTTATCCTT CCAAGAAATT GAAAAAACAA TACAAATTAA CTTGCTATCC AGTTTTTACA CTATAAAAGC TTTTCTTCCC GATATGATGC TACGGGGCCG TGGTTATATA GTAACCATAG CTTCGGTTTT GGGATACATG TCTCCGGCGC GACTCAGTGC ATACGGTGCA TCAAAATCAG GGCTAATTGC ATTACATGAA TCTTTAACTT ATGAGTTGGG GTCTCCTTCT TTGAACCCAC AGGGAATCAA AACTCTATTA GTGTGTCCTG GCCAATTGAA GACCGGAATG TTTCAAGGCG TGGCTACCCC TTCGACCATC TTTGCACCTG AATTAGATCC TGCATTTGTC GCATCAAGTG TAGTTAATGC CATTGAACTG GGAAGAAGAG GAGAAATTAA ATTACCGTTA TATAGCAAAG TAATACCCAT GTTCCGAGCT TTGCCGTGGC CAATTGTTGA AGTCACTAGA AGAATAACTG GTATTGATCA AAGTATGATT GACTTCAAGT CGAAAATATC AAAAGTAGCC AGTAGTGTTT CGTCTTTGAG GAATATTTCG TTGCTGGGGT CAAAAAATGT GTCAACTGAG GTTACTCCGA CATTTGCTGT CGCCGAGTCA ACACCGCAGG AAAACAAGGC GGCTTTGTCT CAGACAGAGA TTTCCTAA
AA Sequence
MFVILSLIID LIYWLNKQFR YISDLIIGNV FDPRFDIVLV TGGVTGLGRE LVLQIISKGA QVVVLDILEP LEEDLNTVGL THYKCDVSDP QDVLRTQKLV RKEIGVVTVL INNAGIATGK PVLDLSFQEI EKTIQINLLS SFYTIKAFLP DMMLRGRGYI VTIASVLGYM SPARLSAYGA SKSGLIALHE SLTYELGSPS LNPQGIKTLL VCPGQLKTGM FQGVATPSTI FAPELDPAFV ASSVVNAIEL GRRGEIKLPL YSKVIPMFRA LPWPIVEVTR RITGIDQSMI DFKSKISKVA SSVSSLRNIS LLGSKNVSTE VTPTFAVAES TPQENKAALS QTEIS*