| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P87186 | LEU2 | LEU3_CANAL | SP | Candida albicans (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 653 | 0.0 | 338/373 (90%) | 342/373 (91%) | |
| P07139 | LEU2 | LEU3_CANMA | SP | Candida maltosa (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 643 | 0.0 | 328/371 (88%) | 338/371 (91%) | |
| Q12591 | LEU2 | TrEMBL | Candida maltosa (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85). | 643 | 0.0 | 327/371 (88%) | 339/371 (91%) | ||
| Q12590 | LEU2 | TrEMBL | Candida maltosa (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85). | 637 | 0.0 | 326/371 (87%) | 335/371 (90%) | ||
| O94114 | LEU2 | LEU3_PICST | SP | Pichia stipitis (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 588 | e-167 | 296/370 (80%) | 322/370 (87%) | |
| P41926 | LEU2 | LEU3_YAMOH | SP | Yamadazyma ohmeri (Yeast) (Pichia ohmeri) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 571 | e-162 | 287/369 (77%) | 318/369 (86%) | |
| P08791 | LEU2 | LEU3_PICJA | SP | Pichia jadinii (Yeast) (Candida utilis) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 533 | e-150 | 275/364 (75%) | 305/364 (83%) | |
| Q9HDQ1 | LEU2 | TrEMBL | Hansenula anomala (Yeast) (Candida pelliculosa) | Beta-isopropylmalate dehydrogenase (EC 1.1.1.85). | 526 | e-148 | 271/365 (74%) | 300/365 (82%) | ||
| Q96WT9 | LEU2 | LEU3_SACEX | SP | Saccharomyces exiguus (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 523 | e-147 | 264/369 (71%) | 301/369 (81%) | |
| P41766 | LEU2 | LEU3_KLUMA | SP | Kluyveromyces marxianus (Yeast) (Kluyveromyces fragilis) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 520 | e-146 | 267/365 (73%) | 301/365 (82%) | |
| O14429 | LEU2 | LEU3_CANGA | SP | Candida glabrata (Yeast) (Torulopsis glabrata) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 519 | e-146 | 264/365 (72%) | 296/365 (81%) | |
| P23390 | LEU2 | LEU3_KLULA | SP | Kluyveromyces lactis (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 515 | e-145 | 261/365 (71%) | 299/365 (81%) | |
| P04173 | LEU2 | LEU3_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 508 | e-143 | 261/364 (71%) | 294/364 (80%) | |
| Q01987 | LEU2 | LEU3_CANBO | SP | Candida boidinii (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 508 | e-143 | 261/369 (70%) | 301/369 (81%) | |
| Q8NKB8 | LEU2 | TrEMBL | Arxula adeninivorans (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85). | 503 | e-141 | 255/366 (69%) | 295/366 (80%) | ||
| Q9P3Y0 | LEU2 | TrEMBL | Zygosaccharomyces bailii | Beta-isopropylmalate dehydrogenase (EC 1.1.1.85). | 502 | e-141 | 257/365 (70%) | 294/365 (80%) | ||
| Q96WI0 | LEU2 | TrEMBL | Zygosaccharomyces rouxii (Candida mogii) | Isopropylmalate dehydrogenase. | 500 | e-140 | 255/365 (69%) | 292/365 (80%) | ||
| Q9HDQ5 | LEU2 | TrEMBL | Candida rugosa (Yeast) (Candida cylindracea) | Putative beta-isopropylmalate dehydrogenase (EC 1.1.1.85). | 496 | e-139 | 253/363 (69%) | 291/363 (80%) | ||
| P34733 | LEU2 | LEU3_PICAN | SP | Pichia angusta (Yeast) (Hansenula polymorpha) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 489 | e-137 | 249/366 (68%) | 295/366 (80%) | |
| O60027 | LEU2 | LEU3_ASHGO | SP | Ashbya gossypii (Yeast) (Eremothecium gossypii) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 467 | e-130 | 232/368 (63%) | 283/368 (76%) | |
| Q12592 | LEU2 | TrEMBL | Candida maltosa (Yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85). | 444 | e-124 | 221/244 (90%) | 232/244 (95%) | ||
| Q877A9 | TrEMBL | Aspergillus oryzae | Hypothetical protein. | 400 | e-110 | 202/365 (55%) | 264/365 (72%) | 2/365 (0%) | ||
| P18120 | LEU2 | LEU3_YARLI | SP | Yarrowia lipolytica (Candida lipolytica) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 395 | e-109 | 212/364 (58%) | 261/364 (71%) | 7/364 (1%) |
| P34738 | LEU-1 | LEU3_NEUCR | SP | Neurospora crassa | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 387 | e-106 | 206/369 (55%) | 260/369 (70%) | 3/369 (0%) |
| P87256 | LEU2A | LE3A_ASPNG | SP | Aspergillus niger | 3-isopropylmalate dehydrogenase A (EC 1.1.1.85) (Beta-IPM dehydrogenase A) (IMDH A) (3-IPM-DH A). | 380 | e-104 | 198/365 (54%) | 256/365 (70%) | 2/365 (0%) |
| Q9P8C1 | LEUA | TrEMBL | Phaeosphaeria nodorum (Septoria nodorum) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85). | 378 | e-104 | 198/366 (54%) | 253/366 (69%) | 2/366 (0%) | |
| Q9Y897 | LEUC | LEU3_MYCGR | SP | Mycosphaerella graminicola (Septoria tritici) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 373 | e-102 | 193/368 (52%) | 251/368 (68%) | 2/368 (0%) |
| P18869 | LEU1 | LEU3_SCHPO | SP | Schizosaccharomyces pombe (Fission yeast) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 345 | 4e-94 | 185/373 (49%) | 246/373 (65%) | 9/373 (2%) |
| O59930 | LEU2 | LEU3_PHACH | SP | Phanerochaete chrysosporium | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 317 | 2e-85 | 179/383 (46%) | 236/383 (61%) | 14/383 (3%) |
| Q12545 | LEU2 | LEU3_CEPAC | SP | Cephalosporium acremonium (Acremonium chrysogenum) | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH). | 294 | 1e-78 | 162/380 (42%) | 229/380 (60%) | 14/380 (3%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- isodh Isocitrate/isopropylmalate dehydrogenase 664.0 7.7e-196 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- isodh 1/1 7 361 .. 1 403 [] 664.0 7.7e-196
CDS Sequence
ATGTCTGTTA AAACCAAAAC CATTACTGTC TTGCCTGGTG ACCATGTCGG TACCGAAATT GTCAATGAAG CAATCAAAGT CTTGAAAGCA ATTGAAGCTG CCACTCCCTA CCAAAAAATC CAATTTGATT TCAAACACCA CTTGATTGGT GGTGCTGCCA TTGATGCCAC TGGCGTCCCG CTTCCAGATG ATGCTCTTGA AAGTGCTAAA TCATCCGATG CAGTTTTGTT GGGTGCTGTT GGTGGACCCA AATGGGGTAC TGGCACTGTT CGTCCTGAAC AAGGATTATT GAAAATCCGT AAAGAATTGA ACCTTTATGC CAACATTAGA CCATGTAATT TTGCCAGTGA CTCGTTATTA GAATTGTCTC CATTAAAAGC TGAAGTGGTC AAAGGAACCA ATTTAATTAT TGTTCGTGAA TTAGTTGGTG GTATATATTT TGGTGAACGT CAAGAACAAG AAGAAAGTGA AGACAAAAAA ACAGCTTGGG ATACAGAAAA GTATACTGTT GACGAAGTTA CTCGTATCAC TCGTATGGCA GCATTTATGG CTTTGCAGCA CAATCCACCA TTGCCAATAT GGTCTTTGGA CAAAGCTAAT GTTTTGGCAT CGTCGAGATT GTGGAGAAAG ACCGTTGATA AAGTGATTTC TGAAGAATTT CCAGCTTTGT CTGTGCAGCA TCAATTGATT GATTCGGCTG CAATGATTTT GATCCAAAAC CCAACCAAAT TGAACGGTAT CATCATTACA TCTAACATGT TTGGTGATAT CATCTCAGAT GAGGCATCCG TTATCCCAGG ATCTTTGGGT TTATTGCCAT CTGCTTCATT GGCTTCATTG CCAGATACCA ACACTGCTTT TGGTCTTTAT GAGCCTTGCC ATGGGTCTGC TCCAGATTTA CCAGCCAACA AAGTGAATCC AATTGCTACA ATCTTGTCTG CCGCTTCCAT GTTGAGATTA TCCTTGGATT GTGTTAAGGA AGCTGAAGCA TTGGAAGAAG CTGTCAAACA GGTTTTGGAT AGCGGTATCA GAACAGCAGA TTTAAGAGGT ACTAGCTCTA CTACAGAAGT CGGTGACGCA ATAGCCGAAA CAGTCACTAA AATTTTAAAA CAAAATACAT AA
AA Sequence
MSVKTKTITV LPGDHVGTEI VNEAIKVLKA IEAATPYQKI QFDFKHHLIG GAAIDATGVP LPDDALESAK SSDAVLLGAV GGPKWGTGTV RPEQGLLKIR KELNLYANIR PCNFASDSLL ELSPLKAEVV KGTNLIIVRE LVGGIYFGER QEQEESEDKK TAWDTEKYTV DEVTRITRMA AFMALQHNPP LPIWSLDKAN VLASSRLWRK TVDKVISEEF PALSVQHQLI DSAAMILIQN PTKLNGIIIT SNMFGDIISD EASVIPGSLG LLPSASLASL PDTNTAFGLY EPCHGSAPDL PANKVNPIAT ILSAASMLRL SLDCVKEAEA LEEAVKQVLD SGIRTADLRG TSSTTEVGDA IAETVTKILK QNT*