| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P22138 | RPA2 | RPA2_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | DNA-directed RNA polymerase I 135 kDa polypeptide (EC 2.7.7.6) (A135) (RNA polymerase I subunit 2). | 1910 | 0.0 | 931/1190 (78%) | 1041/1190 (87%) | 27/1190 (2%) |
| Q9P7X8 | RPA2 | RPA2_SCHPO | SP | Schizosaccharomyces pombe (Fission yeast) | Probable DNA-directed RNA polymerase I polypeptide 2 (EC 2.7.7.6) (RNA polymerase I subunit 2). | 1606 | 0.0 | 775/1178 (65%) | 950/1178 (80%) | 19/1178 (1%) |
| O74633 | ACR-2 | RPA2_NEUCR | SP | Neurospora crassa | DNA-directed RNA polymerase I polypeptide 2 (EC 2.7.7.6) (RNA polymerase I subunit 2). | 1497 | 0.0 | 761/1200 (63%) | 924/1200 (77%) | 38/1200 (3%) |
| P70700 | POLR1B | RPA2_MOUSE | SP | Mus musculus (Mouse) | DNA-directed RNA polymerase I 135 kDa polypeptide (EC 2.7.7.6) (RNA polymerase I subunit 2) (RPA135). | 975 | 0.0 | 522/1154 (45%) | 736/1154 (63%) | 8/1154 (0%) |
| Q9H9Y6 | POLR1B | RPA2_HUMAN | SP | Homo sapiens (Human) | DNA-directed RNA polymerase I 135 kDa polypeptide (EC 2.7.7.6) (RNA polymerase I subunit 2) (RPA135). | 935 | 0.0 | 486/1047 (46%) | 681/1047 (65%) | 5/1047 (0%) |
| O54888 | POLR1B | RPA2_RAT | SP | Rattus norvegicus (Rat) | DNA-directed RNA polymerase I 135 kDa polypeptide (EC 2.7.7.6) (RNA polymerase I subunit 2) (RPA135) (RNA polymerase I 127 kDa subunit). | 900 | 0.0 | 505/1172 (43%) | 701/1172 (59%) | 26/1172 (2%) |
| Q9VPP3 | RPI135 | TrEMBL | Drosophila melanogaster (Fruit fly) | RPI135 protein (EC 2.7.7.6) (SD02110p) (DNA-directed RNA polymerase beta chain). | 877 | 0.0 | 477/1160 (41%) | 701/1160 (60%) | 11/1160 (0%) | |
| Q27493 | F14B4.3 | TrEMBL | Caenorhabditis elegans | F14B4.3 protein (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 876 | 0.0 | 470/1106 (42%) | 676/1106 (61%) | 15/1106 (1%) | |
| P20028 | RPI135 | RPA2_DROME | SP | Drosophila melanogaster (Fruit fly) | DNA-directed RNA polymerase I 135 kDa polypeptide (EC 2.7.7.6) (RNA polymerase I subunit 2). | 875 | 0.0 | 476/1160 (41%) | 701/1160 (60%) | 11/1160 (0%) |
| P28365 | RPA2 | RPA2_EUPOC | SP | Euplotes octocarinatus | DNA-directed RNA polymerase I second largest subunit (EC 2.7.7.6) (RNA polymerase I subunit 2). | 860 | 0.0 | 499/1179 (42%) | 712/1179 (60%) | 42/1179 (3%) |
| Q9FXG4 | F1N18.2 | TrEMBL | Arabidopsis thaliana (Mouse-ear cress) | F1N18.2 protein (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 832 | 0.0 | 471/1128 (41%) | 679/1128 (60%) | 73/1128 (6%) | |
| Q9C8S4 | T1P2.15 | TrEMBL | Arabidopsis thaliana (Mouse-ear cress) | DNA-directed RNA polymerase subunit, putative (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 829 | 0.0 | 468/1098 (42%) | 674/1098 (61%) | 45/1098 (4%) | |
| Q8SSB7 | ECU03_0440 | TrEMBL | Encephalitozoon cuniculi | DNA-directed RNA polymerase I, second largest subunit (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 736 | 0.0 | 441/1162 (37%) | 640/1162 (55%) | 26/1162 (2%) | |
| Q8LNU6 | OSJNBA0041P03.1 | TrEMBL | Oryza sativa (japonica cultivar-group) | Putative DNA-directed RNA polymerase I subunit, 5'-partial (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain) (Fragment). | 660 | 0.0 | 382/883 (43%) | 521/883 (59%) | 51/883 (5%) | |
| Q98S72 | RPA2 | TrEMBL | Guillardia theta (Cryptomonas phi) | DNA-directed RNA polymerase I 135K chain (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 620 | e-176 | 363/1013 (35%) | 570/1013 (56%) | 39/1013 (3%) | |
| Q9BSR4 | POLR1B | TrEMBL | Homo sapiens (Human) | POLR1B protein (Fragment). | 583 | e-165 | 298/603 (49%) | 404/603 (66%) | 1/603 (0%) | |
| Q9H6S8 | TrEMBL | Homo sapiens (Human) | Hypothetical protein FLJ21921 (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 502 | e-140 | 245/441 (55%) | 316/441 (71%) | |||
| Q95JH9 | TrEMBL | Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) | Hypothetical protein (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 465 | e-129 | 227/443 (51%) | 310/443 (69%) | 1/443 (0%) | ||
| Q9NW08 | POLR3B | RPC2_HUMAN | SP | Homo sapiens (Human) | DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2) (RPC2). | 451 | e-125 | 349/1110 (31%) | 536/1110 (48%) | 55/1110 (4%) |
| Q8ZYQ9 | PAE0665 | TrEMBL | Pyrobaculum aerophilum | DNA-directed RNA polymerase subunit B (rpoB). | 420 | e-116 | 332/1052 (31%) | 513/1052 (48%) | 46/1052 (4%) | |
| Q9V649 | RPIII128 | TrEMBL | Drosophila melanogaster (Fruit fly) | RPIII128 protein (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain). | 420 | e-116 | 328/1065 (30%) | 509/1065 (47%) | 66/1065 (6%) | |
| Q8MRD5 | RPIII128 | TrEMBL | Drosophila melanogaster (Fruit fly) | LD14594p (EC 2.7.7.6) (DNA-directed RNA polymerase beta chain) (Fragment). | 420 | e-116 | 328/1065 (30%) | 509/1065 (47%) | 66/1065 (6%) | |
| Q8SQY8 | ECU11_0370 | TrEMBL | Encephalitozoon cuniculi | DNA-directed RNA polymerase III subunit 2 (EC 2.7.7.6) (130kDa subunit) (DNA-directed RNA polymerase beta chain). | 413 | e-114 | 331/1059 (31%) | 504/1059 (47%) | 60/1059 (5%) | |
| P25167 | RPIII128 | RPC2_DROME | SP | Drosophila melanogaster (Fruit fly) | DNA-directed RNA polymerase III 128 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2). | 410 | e-113 | 328/1065 (30%) | 509/1065 (47%) | 66/1065 (6%) |
| P22276 | RPC2 | RPC2_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | DNA-directed RNA polymerase III 130 kDa polypeptide (EC 2.7.7.6) (C128) (RNA polymerase III subunit 2). | 408 | e-112 | 321/1037 (30%) | 506/1037 (48%) | 57/1037 (5%) |
| Q42877 | RPB2 | RPB2_LYCES | SP | Lycopersicon esculentum (Tomato) | DNA-directed RNA polymerase II 135 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2). | 404 | e-111 | 339/1166 (29%) | 527/1166 (45%) | 83/1166 (7%) |
| Q10233 | RPC2 | RPC2_SCHPO | SP | Schizosaccharomyces pombe (Fission yeast) | Putative DNA-directed RNA polymerase III 130 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2). | 404 | e-111 | 340/1139 (29%) | 543/1139 (47%) | 60/1139 (5%) |
| O59226 | PH1546 | TrEMBL | Pyrococcus horikoshii | 1117AA long hypothetical DNA-directed RNA polymerase subunit B. | 402 | e-110 | 332/1113 (29%) | 531/1113 (47%) | 50/1113 (4%) | |
| P31814 | RPOB | RPOB_THECE | SP | Thermococcus celer | DNA-directed RNA polymerase subunit B (EC 2.7.7.6). | 402 | e-110 | 328/1120 (29%) | 526/1120 (46%) | 57/1120 (5%) |
| Q8CFI7 | TrEMBL | Mus musculus (Mouse) | Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa. | 401 | e-110 | 336/1108 (30%) | 525/1108 (47%) | 81/1108 (7%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- RNA_pol_Rpb2_6 RNA polymerase Rpb2, domain 6 600.9 7.8e-177 1 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2 154.3 2.1e-42 1 RNA_pol_Rpb2_3 RNA polymerase Rpb2, domain 3 112.5 8.3e-30 1 RNA_pol_Rpb2_1 RNA polymerase beta subunit 92.7 7.6e-24 1 RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7 45.7 1e-09 1 RNA_pol_Rpb2_5 RNA polymerase Rpb2, domain 5 28.6 0.00014 1 Orthopox_C1 Orthopoxvirus C1 protein -75.5 9.8 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- RNA_pol_Rpb2_2 1/1 194 383 .. 1 223 [] 154.3 2.1e-42 RNA_pol_Rpb2_1 1/1 33 448 .. 1 226 [] 92.7 7.6e-24 Orthopox_C1 1/1 292 495 .. 1 214 [] -75.5 9.8 RNA_pol_Rpb2_3 1/1 463 532 .. 1 74 [] 112.5 8.3e-30 RNA_pol_Rpb2_5 1/1 630 671 .. 1 77 [] 28.6 0.00014 RNA_pol_Rpb2_6 1/1 676 1042 .. 1 417 [] 600.9 7.8e-177 RNA_pol_Rpb2_7 1/1 1044 1167 .. 1 92 [] 45.7 1e-09
CDS Sequence
ATGACATTGG CGAAATTTAG AACTTTGGAA AGAGAAAAGA GATTTCAAAA TCCACCAAAG GATATGGACT CATATCCGTT GTTGAAGGAT GCTGTTGCAC CTCATGTGGG ATCATTTAAT GCGTTGATGG ATGGTCCAGA CGGAGGTTTA TTGAATCTTG CTGTAAAAGA TATTGGGTCC AAAACTATTT TTGATACACC AGAAACTTCT GGACGTTTAG GTAATAAATT GAAAATCAGG GTTGACTCAG TACAGTTGGC CAAACCAAGC GTTCCTGCTA ATGATAAATT ATCTTTGAAC AGAAAAACAT TTCCAAGTGA ATGTAGAGAA AGAATGGTAA CATATAGATC AAGATTAATG TTGAATGTTA CTTGGAGTGT GAATGACGAA GAAGAAGTGC TGGAAGTGAG AGAAGCAGGT CAAATACCAA TTATGTTAAA GTCCAACAGA TGTCATTTAG AAAAATTATC ACCTAACCAA TTAGTGGAAG CTAAGGAAGA GAGTGACGAG TTAGGTGGAT ATTTTATTGT TAATGGTATT GAAAAATTGA TCCGTATGTT GATTGTGCAA AGACGTAATC ATCCCATGGC CATTATCCGT CCTTCATTTG GAAACCGTGG TGCTTCTTAC ACAAAATTCG GTATCCAAAT AAGATCAGTA AGACCAGATC AGACATCACA AACAAATGTA TTACATTATT TAAATGATGG TAATGTTACT TTTAGATTTT CATGGAGAAA GAATGAATTT TTGGTTCCTG TTGTGATGAT CTTGAAAGCA TTAATTGAAA CCAACGACCG TGAAATTTTC GATGGTATCG TAGGAAATGA TACTGAAAAC TCGTTTTTAA CTGATCGTTT GGAATTGTTG TTAAGAACTT ACAAAACATA CAATTTGTAC TCCCAACAAG AAACTTTAGC TTATTTGGGT GACAAGTTCA GAGTTGTTTT TGGTGCATCA CCAGATATGT CAGATATTGA AGTCGGTAAA GAAGTTTTGA AAAGAATTGT CTTGGTTCAT TTGCCTAATA ATGCTGACAA GTTTAGAATG TTATTGTTTA TGATTAGAAA ATTGTATTCA TTGGTCGCTG GAGACTGTGC TCCTGATAAC CCAGATGCAA CCCAACATCA AGAAGTTTTG TTGGGAGGTT TCCTTTATGG TATGATTATC AAAGAGAAAA TTGAAGAGTA CTTGCAAAAC ATTAAATTGC AAATTCAATC TGATATTAAT CGTGGTGTTG GTATAAACTT TGACGATAGA AAATATATGA CCAGGGTATT CCTGAGAATC AATGAGAACA TTGGTCAAAA ATTGCAATAT TTTTTAAGTA CTGGTAACTT GGTGTCCCAG TCTGGTTTAG ATTTGCAACA AGTTTCTGGT TATACCGTTG TTGCTGAAAA AATTAACTTT TATCGTTTCA TTTCTCATTT CAGAATGGTC CACCGTGGTT CCTTCTTTGC TGAATTAAAA ACTACTACTG TTAGAAAATT ATTGCCTGAA TCTTGGGGGT TCCTTTGTCC TGTCCATACC CCGGATGGTT CTCCTTGTGG TTTATTAAAT CACTTGTCGC ATAAATGTAA AATTGCCACT GAGGCATCCG ACGTGTCACA AGTTCCAAAG GCTTTAACCC AATTGGGTGT TTTACCGGCC GACTCATTTG CAGCTGGCCC AAACTTGTGC TGTGTTCAAT TGGATGGTAA AATTGTTGGT TGGACGACAC ATGAACAAGG TAGAATTGTC GCTGATACAT TGAGATACTG GAAAGTCAAT GGTGGTCACG GATTGCCTTT AGATTTAGAA ATTGGTTATG TTCCACCTTC AAATAAAGGT CAGTATCCTG GTTTGTACAT TTTTGGTGGC CACTCTAGAA TGATGAGACC AGTGAAGTAT TTACCCTTGG ATAAAGAGGA TATCGTTGGT CCATTTGAAC AAGTCTACAT GAATGTAGCT GTAACTCCAG AAGAAATTGA GAATAACATT CACAGTCATG TTGAATTTAC CCCAACTAAC ATATTATCCA TTTTGGCTAA TTTAACACCC TTTTCTGATT TCAATCAATC ACCAAGAAAT ATGTATCAAT GTCAAATGGG TAAGCAAACA ATGGGTACTC CTGGTACTGC ATTGGTCCAT AGATCAGACA ACAAGTTGTA CCGTTTACAA ACTGGTCAAA CACCAATTGT TAAAGCCAAC TTGTATGATG ACTACGGAAT GGACAATTTC CCTAATGGTA TGAATGCTAT TGTCGCTGTT ATTTCATACA CTGGTTACGA TATGGATGAT GCGATGATAA TAAACAAATC TGCAGATGAA AGAGGTTTTG GTTATGGTAC TGTTTATAAA ACTGAGAAAG TCGATTTGTC ACAATCAAGA AGAAGAGGTG ATCCAATAAC ACAACATTTT GGTTTTGGTA GTGATGAATG GCCAGAAGCA TGGAAGGAAA AATTAGACGC TGATGGTTTG CCATTGATTG GTGTTAAAGT TGAAGAAGGT GATCCAATAG TGGCATATTA TGATGATACT TTGGGTAAAA CTAAAGTTAA GACTTACCAT TCATCGGAAC CAGCATACAT TGAAGAAGTC AAGTTATTAG GTGACGACAG CAATGAACAA GAGGGTCAAC AAATAACTAT CAAATACAGA ATCACAAGAC AACCATTAAT TGGAGACAAA TTCTCTTCTA GACATGGTCA GAAAGGTGTT TGTTCTAGAA AATGGCCACA AATTGACATG CCATTTACTG AGTCAGGTAT GCAACCCGAT GTCATCATTA ACCCACATGC GTTCCCATCT CGTATGACAA TTGGTATGTT TGTTGAATCT CTTGCTGGTA AGGCTGGTGC CTTACACGGT ATTGCCCAGG ATTCTACCCC TTGGAAATTC AATGAACAAG ATACACCAGC AGACTACTTT GGTGAGCAAT TGCTCAAAGC TGGTTATAAC TACCATGGTA ATGAGCCAAT GTACTCTGGT GCCACTGGGG AAGAGTTGCG TTGTGACATT TACATTGGAT GTGTTTACTA TCAAAGATTG AGACATATGG TCAACGATAA GTTCCAAGTT AGATCTACTG GACCTGTTAA TTCATTGACA ATGCAACCTG TGAAAGGTAG AAAGAGATCC GGTGGTATTC GTGTAGGTGA GATGGAAAGA GATGCTTTGA TTGGTCATGG TACTTCTTTC TTGTTGCAAG ATAGATTGTT AAATTGTTCA GATTACACAC AGACACCAGT CTGTCGCTCA TGTGGATCCA TCTTGACTAC ACAAACGTCA GTTCCAAGAA TTGGAAGCAT GGCAAGTATC AGATGTAGAA GATGTGCAGT CGGCTTGGAC AAATATGAAG GATATGCAGC TGATTCAGAT ATATGGGAAG ATGGACATGG CAAGAAATTT GTGGGTGGTG ACGATACCAC AACTGTGGCA ATACCTTTTG TATTGAAATA TTTGGATAGT GAGTTGTCGG CAATGGGTAT AAAGATGCGT TATAATGTTG AACCAAAATA A
AA Sequence
MTLAKFRTLE REKRFQNPPK DMDSYPLLKD AVAPHVGSFN ALMDGPDGGL LNLAVKDIGS KTIFDTPETS GRLGNKLKIR VDSVQLAKPS VPANDKLSLN RKTFPSECRE RMVTYRSRLM LNVTWSVNDE EEVLEVREAG QIPIMLKSNR CHLEKLSPNQ LVEAKEESDE LGGYFIVNGI EKLIRMLIVQ RRNHPMAIIR PSFGNRGASY TKFGIQIRSV RPDQTSQTNV LHYLNDGNVT FRFSWRKNEF LVPVVMILKA LIETNDREIF DGIVGNDTEN SFLTDRLELL LRTYKTYNLY SQQETLAYLG DKFRVVFGAS PDMSDIEVGK EVLKRIVLVH LPNNADKFRM LLFMIRKLYS LVAGDCAPDN PDATQHQEVL LGGFLYGMII KEKIEEYLQN IKLQIQSDIN RGVGINFDDR KYMTRVFLRI NENIGQKLQY FLSTGNLVSQ SGLDLQQVSG YTVVAEKINF YRFISHFRMV HRGSFFAELK TTTVRKLLPE SWGFLCPVHT PDGSPCGLLN HLSHKCKIAT EASDVSQVPK ALTQLGVLPA DSFAAGPNLC CVQLDGKIVG WTTHEQGRIV ADTLRYWKVN GGHGLPLDLE IGYVPPSNKG QYPGLYIFGG HSRMMRPVKY LPLDKEDIVG PFEQVYMNVA VTPEEIENNI HSHVEFTPTN ILSILANLTP FSDFNQSPRN MYQCQMGKQT MGTPGTALVH RSDNKLYRLQ TGQTPIVKAN LYDDYGMDNF PNGMNAIVAV ISYTGYDMDD AMIINKSADE RGFGYGTVYK TEKVDLSQSR RRGDPITQHF GFGSDEWPEA WKEKLDADGL PLIGVKVEEG DPIVAYYDDT LGKTKVKTYH SSEPAYIEEV KLLGDDSNEQ EGQQITIKYR ITRQPLIGDK FSSRHGQKGV CSRKWPQIDM PFTESGMQPD VIINPHAFPS RMTIGMFVES LAGKAGALHG IAQDSTPWKF NEQDTPADYF GEQLLKAGYN YHGNEPMYSG ATGEELRCDI YIGCVYYQRL RHMVNDKFQV RSTGPVNSLT MQPVKGRKRS GGIRVGEMER DALIGHGTSF LLQDRLLNCS DYTQTPVCRS CGSILTTQTS VPRIGSMASI RCRRCAVGLD KYEGYAADSD IWEDGHGKKF VGGDDTTTVA IPFVLKYLDS ELSAMGIKMR YNVEPK*