| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P50942 | YNL106C | YNK6_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Hypothetical 133.3 kDa protein in CYB5-LEU4 intergenic region. | 777 | 0.0 | 428/927 (46%) | 590/927 (63%) | 28/927 (3%) |
| Q12271 | INP53 | TrEMBL | Saccharomyces cerevisiae (Baker's yeast) | YOR3231W from chromosome XV. | 775 | 0.0 | 419/897 (46%) | 580/897 (64%) | 10/897 (1%) | |
| O43001 | SPBC2G2.02 | TrEMBL | Schizosaccharomyces pombe (Fission yeast) | Phosphatidylinositol phosphate phosphatase, synaptojanin-like. | 594 | e-168 | 349/909 (38%) | 518/909 (56%) | 8/909 (0%) | |
| P40559 | YIL002C | YIA2_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Hypothetical 108.4 kDa protein in BET1-PAN1 intergenic region. | 445 | e-123 | 279/917 (30%) | 462/917 (50%) | 23/917 (2%) |
| Q8I7P4 | TrEMBL | Dictyostelium discoideum (Slime mold) | Inositol 5-phosphatase 3. | 405 | e-111 | 294/944 (31%) | 455/944 (48%) | 64/944 (6%) | ||
| O43426 | SYNJ1 | SYJ1_HUMAN | SP | Homo sapiens (Human) | Synaptojanin 1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1). | 385 | e-105 | 263/823 (31%) | 403/823 (48%) | 36/823 (4%) |
| O94984 | KIAA0910 | TrEMBL | Homo sapiens (Human) | Hypothetical protein KIAA0910 (Fragment). | 385 | e-105 | 263/823 (31%) | 403/823 (48%) | 36/823 (4%) | |
| Q8CHC4 | MKIAA0910 | TrEMBL | Mus musculus (Mouse) | MKIAA0910 protein (Fragment). | 384 | e-105 | 261/823 (31%) | 404/823 (49%) | 36/823 (4%) | |
| Q62910 | SYNJ1 | SYJ1_RAT | SP | Rattus norvegicus (Rat) | Synaptojanin 1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1). | 382 | e-104 | 260/823 (31%) | 403/823 (48%) | 36/823 (4%) |
| O18964 | SYNJ1 | SYJ1_BOVIN | SP | Bos taurus (Bovine) | Synaptojanin 1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1) (p150) (Fragment). | 381 | e-104 | 262/823 (31%) | 403/823 (48%) | 36/823 (4%) |
| Q9USQ6 | SPBC577.13 | TrEMBL | Schizosaccharomyces pombe (Fission yeast) | Putative inositol polyphosphate phosphatase family member. | 374 | e-102 | 279/909 (30%) | 439/909 (48%) | 27/909 (2%) | |
| Q9H226 | TrEMBL | Homo sapiens (Human) | Synaptojanin 2. | 372 | e-101 | 271/843 (32%) | 421/843 (49%) | 33/843 (3%) | ||
| O15056 | SYNJ2 | SYJ2_HUMAN | SP | Homo sapiens (Human) | Synaptojanin 2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2) (Fragment). | 372 | e-101 | 271/843 (32%) | 421/843 (49%) | 33/843 (3%) |
| Q8IZA8 | TrEMBL | Homo sapiens (Human) | Synaptojanin 2A. | 372 | e-101 | 271/843 (32%) | 421/843 (49%) | 33/843 (3%) | ||
| Q9XUD3 | JC8.10 | TrEMBL | Caenorhabditis elegans | JC8.10a protein (Synaptojanin UNC-26B). | 371 | e-101 | 257/856 (30%) | 421/856 (49%) | 22/856 (2%) | |
| Q9W296 | SYNAPTOJANIN | TrEMBL | Drosophila melanogaster (Fruit fly) | CG6562 protein. | 370 | e-101 | 270/904 (29%) | 424/904 (46%) | 59/904 (6%) | |
| Q9GT42 | JC8.10 | TrEMBL | Caenorhabditis elegans | Synaptojanin UNC-26A (JC8.10b protein). | 366 | e-100 | 256/863 (29%) | 423/863 (49%) | 29/863 (3%) | |
| O55207 | SYNJ2 | SYJ2_RAT | SP | Rattus norvegicus (Rat) | Synaptojanin 2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2). | 358 | 3e-97 | 260/833 (31%) | 398/833 (47%) | 46/833 (5%) |
| Q91ZD9 | TrEMBL | Rattus norvegicus (Rat) | Synaptojanin 2B1. | 358 | 3e-97 | 260/833 (31%) | 398/833 (47%) | 46/833 (5%) | ||
| Q91ZD8 | TrEMBL | Rattus norvegicus (Rat) | Synaptojanin 2B2. | 358 | 3e-97 | 260/833 (31%) | 398/833 (47%) | 46/833 (5%) | ||
| O88399 | SYNJ2 | TrEMBL | Mus musculus (Mouse) | Synaptojanin 2 (EC 3.1.3.56) (Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2). | 356 | 1e-96 | 246/721 (34%) | 366/721 (50%) | 25/721 (3%) | |
| Q9DGN7 | TrEMBL | Lampetra fluviatilis (River lamprey) | Synaptojanin 1. | 352 | 1e-95 | 254/835 (30%) | 404/835 (48%) | 48/835 (5%) | ||
| Q8MR94 | SYNAPTOJANIN | TrEMBL | Drosophila melanogaster (Fruit fly) | SD04710p (Fragment). | 309 | 2e-82 | 203/647 (31%) | 319/647 (49%) | 39/647 (6%) | |
| Q9D2G5 | SYNJ2 | TrEMBL | Mus musculus (Mouse) | Synaptojanin 2. | 278 | 2e-73 | 176/485 (36%) | 257/485 (52%) | 17/485 (3%) | |
| O60162 | SPBC19F5.03 | TrEMBL | Schizosaccharomyces pombe (Fission yeast) | Possibly involved in secretion-by similarity. | 209 | 2e-52 | 139/401 (34%) | 208/401 (51%) | 11/401 (2%) | |
| P32368 | RSD1 | RSD1_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Recessive suppressor of secretory defect. | 206 | 1e-51 | 153/485 (31%) | 236/485 (48%) | 38/485 (7%) |
| Q9VD98 | CG7956 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG7956 protein. | 203 | 1e-50 | 132/397 (33%) | 205/397 (51%) | 6/397 (1%) | |
| Q8MRH8 | CG7956 | TrEMBL | Drosophila melanogaster (Fruit fly) | LD42233p. | 203 | 1e-50 | 132/397 (33%) | 205/397 (51%) | 6/397 (1%) | |
| Q86AE0 | TrEMBL | Dictyostelium discoideum (Slime mold) | Similar to Rattus norvegicus (Rat). phosphoinositide phosphatase SAC1. | 202 | 2e-50 | 135/401 (33%) | 209/401 (52%) | 7/401 (1%) | ||
| Q93641 | F30A10.6 | TrEMBL | Caenorhabditis elegans | F30A10.6 protein. | 201 | 4e-50 | 132/400 (33%) | 197/400 (49%) | 10/400 (2%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Syja_N SacI homology domain 381.5 8.2e-111 1 Exo_endo_phos Endonuclease/Exonuclease/phosphatase fa 123.7 3.5e-33 1 CD2 T-cell surface antigen CD2 protein -206.7 8.3 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- Syja_N 1/1 62 398 .. 1 362 [] 381.5 8.2e-111 Exo_endo_phos 1/1 579 882 .. 1 200 [] 123.7 3.5e-33 CD2 1/1 711 1021 .. 1 438 [] -206.7 8.3
CDS Sequence
atgaagttac tatataagga acaccctcga acattagtac tatattcaga tactttcagt ttatcatttc gaatcaaatc gtccaaagaa ctcgattcca agaaaccaac agttaatgtt gatttaatcc caaacacaaa catcaccaaa gaacaaggtt atagaacatt aattcgaaga gacgtttttg gatgtttagg attaatctat gtggaagatc aaatatatct tgcaattatt acaggggcat taactaatgt tgctcgtccc attgaaaatg aaacagttga taaaatttat tcggtggatt ttgtatcttt aaataatgat gattgggatt ttgttgaatt agatagttca ggatatccta ttgttgttaa tgaagaacaa gatgacgatg ataataatat tactagtgat aggtatgcac gagtacaaca tccatgtttt gaattaagga aattattatc taatggatca ttttattatt ctaatgattt tgatttaacg tcattattac aaaatagagg agttagtagt cctgacacta gaataaattc tattgatcat tataaaccag aatatatgtg gaattcattt ttaatggatg aattgattca tttccgatct aatttagata cttataatca attaattttg gatgataatc ggtttttaac tactgtgatt agagggtttg cgaaaacaac cccgattggc agtaatggtg attccttgac gattatttct aaacaatctt ggaaacgtgc tgggacaaga tataatactc gaggtattga cgataatggg aatgttgcca attttgttga aacggaatat atctattata atccatcgaa atcatcaatt ttcactttca cacaaatcag aggatcggta cctacatttt gggaacaaga ttcaagtttg atgaatccta aaattacttt aacaagatcc acccaagcaa cacaaccagt ttttaataaa cattttggtg atattcttca aagttatgga gtgtgtcata ttgttgattt actttcgaaa actaaatcat cagaagtaca aatatcacaa agataccaac aactttataa tcattgtgac aagaaagaag aaatcgacta tacggcattt gatttccatc atgaaacaaa aattgctgga ggttttgctg gggcaacaaa aattttaccc tatttacaag attcattaaa tctgtttggt tggtttactt atgatatgaa tcgtcaagaa gttattactc gacaagatgg gattttccgt gtaaattgtt tagattgtct tgatcgtact aatttaatcg aacaagttat ttgtcgatcc gttttggaaa atattttaac taatcaaggg atttataata atcgtatggc atttgaagga atgattcaaa aacacaatac attatgggct gataatggtg atgccatatc acaaatttat acggggacca atgccttgaa atcatcattt tcaagatcag gtaaaatgaa ctttgctggg gcattatcag atgttactaa atcagtttca agaatgtatc aaaatacatt tgtcgatggg aaaaaacaac tgacaataga tatattggtt ggagttgatg gaagaaattc ttgtaaagtg aaagtttata atcctgccag tgaatacatt aaaagtaaat taaaagaaca agaaaattca tttacaagtt ttgaaaatgt taaaattttt acagggactt ataatgtcaa tgcatttaac ccgttgatga cgaaaaatat cgatttaact tcttggttgt tcccttctag tgtacaaaat ggtgatggat cattaccgga tatgtatgcc attggattac aagaattgat tgaattaaat gcaagttcga tattaaatgc tgatggtagt agagcattac aatggtcaca attattaaat gaacaattga attcttttca aatggatgaa gaatatgtct tgttaagaac agaatcaatt gctacaatgg cattattttt atatgttaaa aaatccaaag tatcatatgt aacaagagtt gctgggtcat ccaaaaagac tggtttagga ggtatggcag ccaataaagg tgcttgtgga attagatgtt tatttggtac cacgtcattt gcttttgtta catgtcattt agctgctggg acattggccg tcacagaaag atataatgat tattcaacaa taatgcaagg attagttttc ccccgtaatt attatattaa agatcatgat cacgtaatat ggtttggtga tttaaattat cgaattgata ttcccaattt agaatgtcgt caattggtgg ctaatggtgc ttacaaggaa ttattagaaa atgatcaatt aactcgtgaa agaagagatc gaggagcttt taatgaattt aaagaaggtt tagtgaaatt tcctccaact tataaattcg ataaatatac taatgattat gatactagtg aaaaacaaag aactccatca tggacagatc gtgttttatt tttaagtgat aagaaattaa ctactactaa tccattgaaa ttattaaagt atgattctgc tattgatgtc ttgtattctg atcataaagc cgtttatgca agttttgaaa ccacagctaa gattattaat gaacaaatca agaaaaataa attgaatgaa attattctgt ctttatcatt taagaaaata acaccatcac catcgccatc acctgcccca ttaacaacat catcaacaac aacaacaaca acaacaatgt ctcgtacatc aagtttaaca aggtcttcaa cttcaatttt gacaccaact ccagtatcag ctggaggaac cactgattta atacatggat taggtcaaac aacaacaacc actttgtcac tggcaccacc tccgccacct ccggcaagac gtgccatgac aacgccttca actattccac caattgggtt ttcttcaact ccattaattc catctccatt aagttccaat agatcatcac cagcaccatc tataaattca agttcagaaa agaaacatga caccaaacca ccaattccac caatgaaaag aaataccaca ttaaatgata ttaaattatc atcaccatca cttacaaatt ctataaagag tgggaaagtt ttaaaagatg atagtgatgt tgatacaatg aaaaaacttg atgttaaacc aatgattcct aaaaaacctg aaaatttgaa atcaattcat aaagatggaa aattggacaa taatgggaat tcaacatctc aaaacacaaa cggtggtgaa agtggtggtg gcggagtagc cacacccaaa tcaatggcta gttggcaacc attagttcct ggtcgtaaat ag
AA Sequence
MKLLYKEHPR TLVLYSDTFS LSFRIKSSKE LDSKKPTVNV DLIPNTNITK EQGYRTLIRR DVFGCLGLIY VEDQIYLAII TGALTNVARP IENETVDKIY SVDFVSLNND DWDFVELDSS GYPIVVNEEQ DDDDNNITSD RYARVQHPCF ELRKLLSNGS FYYSNDFDLT SLLQNRGVSS PDTRINSIDH YKPEYMWNSF LMDELIHFRS NLDTYNQLIL DDNRFLTTVI RGFAKTTPIG SNGDSLTIIS KQSWKRAGTR YNTRGIDDNG NVANFVETEY IYYNPSKSSI FTFTQIRGSV PTFWEQDSSL MNPKITLTRS TQATQPVFNK HFGDILQSYG VCHIVDLLSK TKSSEVQISQ RYQQLYNHCD KKEEIDYTAF DFHHETKIAG GFAGATKILP YLQDSLNLFG WFTYDMNRQE VITRQDGIFR VNCLDCLDRT NLIEQVICRS VLENILTNQG IYNNRMAFEG MIQKHNTLWA DNGDAISQIY TGTNALKSSF SRSGKMNFAG ALSDVTKSVS RMYQNTFVDG KKQLTIDILV GVDGRNSCKV KVYNPASEYI KSKLKEQENS FTSFENVKIF TGTYNVNAFN PLMTKNIDLT SWLFPSSVQN GDGSLPDMYA IGLQELIELN ASSILNADGS RALQWSQLLN EQLNSFQMDE EYVLLRTESI ATMALFLYVK KSKVSYVTRV AGSSKKTGLG GMAANKGACG IRCLFGTTSF AFVTCHLAAG TLAVTERYND YSTIMQGLVF PRNYYIKDHD HVIWFGDLNY RIDIPNLECR QLVANGAYKE LLENDQLTRE RRDRGAFNEF KEGLVKFPPT YKFDKYTNDY DTSEKQRTPS WTDRVLFLSD KKLTTTNPLK LLKYDSAIDV LYSDHKAVYA SFETTAKIIN EQIKKNKLNE IILSLSFKKI TPSPSPSPAP LTTSSTTTTT TTMSRTSSLT RSSTSILTPT PVSAGGTTDL IHGLGQTTTT TLSLAPPPPP PARRAMTTPS TIPPIGFSST PLIPSPLSSN RSSPAPSINS SSEKKHDTKP PIPPMKRNTT LNDIKLSSPS LTNSIKSGKV LKDDSDVDTM KKLDVKPMIP KKPENLKSIH KDGKLDNNGN STSQNTNGGE SGGGGVATPK SMASWQPLVP GRK*