| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| P38148 | YBR276C | YB9T_YEAST | SP | Saccharomyces cerevisiae (Baker's yeast) | Probable protein-tyrosine phosphatase YBR276C (EC 3.1.3.48). | 257 | 7e-67 | 192/580 (33%) | 280/580 (48%) | 28/580 (4%) |
| Q8X0K3 | B11B23.210 | TrEMBL | Neurospora crassa | Related to protein tyrosine phosphatase PPS1. | 139 | 2e-31 | 85/249 (34%) | 123/249 (49%) | 18/249 (7%) | |
| Q99956 | DUSP9 | DUS9_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4). | 76.3 | 2e-12 | 56/200 (28%) | 91/200 (45%) | |
| Q8N4A4 | TrEMBL | Homo sapiens (Human) | Similar to dual specificity phosphatase 9 (Fragment). | 76.3 | 2e-12 | 56/200 (28%) | 91/200 (45%) | |||
| Q99KC2 | 2310076D10RIK | TrEMBL | Mus musculus (Mouse) | Similar to dual specificity phosphatase 9. | 75.5 | 4e-12 | 57/187 (30%) | 87/187 (46%) | ||
| Q8K1S9 | DUSP9 | TrEMBL | Mus musculus (Mouse) | MAP kinase phosphatase 4. | 75.5 | 4e-12 | 57/187 (30%) | 87/187 (46%) | ||
| Q8NFJ0 | PYST2 | TrEMBL | Homo sapiens (Human) | Dual-specificity phosphatase 7 PYST2-L. | 73.6 | 2e-11 | 54/191 (28%) | 86/191 (45%) | ||
| Q16829 | DUSP7 | DUS7_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2). | 73.6 | 2e-11 | 54/191 (28%) | 86/191 (45%) | |
| Q91Z46 | DUSP7 | DUS7_MOUSE | SP | Mus musculus (Mouse) | Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16). | 73.6 | 2e-11 | 54/191 (28%) | 86/191 (45%) | |
| Q63340 | DUSP7 | DUS7_RAT | SP | Rattus norvegicus (Rat) | Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase MKP-X) (Fragment). | 73.6 | 2e-11 | 54/191 (28%) | 86/191 (45%) | |
| Q8UW48 | DUSP6 | TrEMBL | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) | Dual specificity phosphatase 6, isoform a. | 72.4 | 3e-11 | 54/189 (28%) | 84/189 (44%) | ||
| Q16828 | DUSP6 | DUS6_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1). | 70.9 | 1e-10 | 53/191 (27%) | 86/191 (45%) | |
| Q9DBB1 | DUSP6 | DUS6_MOUSE | SP | Mus musculus (Mouse) | Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3). | 70.9 | 1e-10 | 53/191 (27%) | 86/191 (45%) | |
| Q64346 | DUSP6 | DUS6_RAT | SP | Rattus norvegicus (Rat) | Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3). | 70.9 | 1e-10 | 53/191 (27%) | 86/191 (45%) | |
| Q91663 | TrEMBL | Xenopus laevis (African clawed frog) | Dual specificity protein phosphatase ? (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase X17C). | 70.1 | 2e-10 | 52/191 (27%) | 87/191 (45%) | |||
| Q803B2 | TrEMBL | Brachydanio rerio (Zebrafish) (Danio rerio) | Similar to dual specificity phosphatase 6. | 69.3 | 3e-10 | 52/184 (28%) | 81/184 (44%) | |||
| Q9Y6W6 | DUSP10 | DUSA_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5). | 65.9 | 3e-09 | 52/189 (27%) | 88/189 (46%) | |
| Q8R3L3 | DUSP10 | TrEMBL | Mus musculus (Mouse) | Dual specificity phosphatase 10. | 65.9 | 3e-09 | 52/189 (27%) | 88/189 (46%) | ||
| Q9CSL5 | DUSP10 | TrEMBL | Mus musculus (Mouse) | 2610306G15Rik protein (Fragment). | 65.9 | 3e-09 | 52/189 (27%) | 88/189 (46%) | ||
| Q8BFV3 | DUSP4 | TrEMBL | Mus musculus (Mouse) | Dual specificity protein phosphatase 4. | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | ||
| Q9NSW1 | DKFZP434O1321 | TrEMBL | Homo sapiens (Human) | Hypothetical protein. | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | ||
| Q9PW71 | DUSP4 | DUS4_CHICK | SP | Gallus gallus (Chicken) | Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase-2) (MAP kinase phosphatase-2) (MKP-2). | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | |
| Q13115 | DUSP4 | DUS4_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase-2) (MAP kinase phosphatase-2) (MKP-2) (Dual specificity protein phosphatase hVH2). | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | |
| Q62767 | DUSP4 | DUS4_RAT | SP | Rattus norvegicus (Rat) | Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase-2) (MAP kinase phosphatase-2) (MKP-2). | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | |
| Q13649 | TrEMBL | Homo sapiens (Human) | Threonine, tyrosine phosphatase (Fragment). | 64.7 | 7e-09 | 48/184 (26%) | 86/184 (46%) | |||
| Q9ESS0 | DUSP10 | DUSA_MOUSE | SP | Mus musculus (Mouse) | Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5). | 64.3 | 9e-09 | 51/189 (26%) | 88/189 (46%) | |
| Q7ZVL8 | TrEMBL | Brachydanio rerio (Zebrafish) (Danio rerio) | Similar to dual specificity phosphatase 1. | 63.9 | 1e-08 | 56/197 (28%) | 90/197 (45%) | |||
| P28562 | DUSP1 | DUS1_HUMAN | SP | Homo sapiens (Human) | Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase-1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1). | 63.9 | 1e-08 | 49/184 (26%) | 83/184 (45%) | |
| Q9H9Z5 | TrEMBL | Homo sapiens (Human) | Hypothetical protein FLJ12451 (Dual specificity phosphatase 10). | 63.9 | 1e-08 | 35/89 (39%) | 54/89 (60%) | |||
| Q91790 | TrEMBL | Xenopus laevis (African clawed frog) | Dual specificity protein phosphatase XCL100 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase). | 63.5 | 2e-08 | 48/184 (26%) | 82/184 (44%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- DSPc Dual specificity phosphatase, catalytic 124.6 1.9e-33 1 Uricase Uricase -37.9 9 1 Y_phosphatase Protein-tyrosine phosphatase -64.6 0.067 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- Uricase 1/1 450 686 .. 1 174 [] -37.9 9 Y_phosphatase 1/1 887 1061 .. 1 271 [] -64.6 0.067 DSPc 1/1 880 1064 .. 1 172 [] 124.6 1.9e-33
CDS Sequence
atgatgagta taacaagaac tagtactgcc actacaacaa ccacaacagc atcagacatt tctcaaatgg aaattaaaga gctggaaata gaacctagac ctaaaagtac agataataat tcttgttctt gttctagttc tagttcttca tccttaatac catctaacac cactaaatct aatcatattc ataaaccaat agctagaaga aatattccca ttgaattgaa agacgataat attgatggtt taaaccccac agaaaaagaa aataatatga caaaatgtat ccccaataca aaaattgatt cttcttcttc ttctactaat tcaacttcaa ctccacttat accttctgat attcatcgtg catgtaaaag atcttcatct tcttcaaatg atctaatata tgaaagagat agatttagag ctagattgaa aagttttaat gatacacaac tgcataataa tcaacatgaa cctccaccag gaacaacaac aaaaatggaa tcgacttcta actccaccat taatggaatt aatgaactgt gtgaaatatg tgatgaaata agtgttactg ttaaaacagc aaaattaaat attgataaaa atccacttga taattcaaca atgttttata aactgctacc caattattat cccgataagg aagatggaat gataacaatt cccgtgaaac aattaaattt ggatcaagta ttggaagttt ttaaatggta tttcaattca aatttaccaa atacaaaaga tatgtttcct tggcttcatg gatttcataa atataatttt gctcaacgtt catttttttt acatcaacaa caacaattac aacaaaaatt ggataacagt agtactaata ctagtaatac caatttccaa gattctatga atcataatga attgtttact gattatcatt tatctcgacc agatgatatt cgatttttaa tgtgtattaa tgatgaaagt ttaccagtta atttacataa tacggtgaaa ttgacagaaa tattgacaaa aatcgatgtt tcaaaatcgg aaattaaaga aatcattaaa aagatctggt taaatgataa aaatggaatt gaaactgaaa ctgaaactga gactgagact gattcaagtt ttattgaatt attggtgact gattgtataa aattaaatgt tttaccgata tttttaaatt tagatcctga aagagggatt tcattaagaa attttcaaat tcaagtggca aaattatcaa gttgttccga ttttataatt tatggaattg atgaattgaa aattcaatca ataacaagaa ttctttggtt agctcaaagg tatgaacgtc aacaacgaga aattgaaatt aaagaatcag gtaaaggtaa tcaacaacaa caaacatata atatatttgt tttaaaaaat gatttaactc aatgttatga aaaattacct ccttctacta caattatgaa tactatacaa tcatttgcta aatatctgaa aattgatact tcagggttat tttataaacc aataaatcaa tatcttttaa atgattataa tttaccatta tatgaaaaaa ttgaaacggc gaaaatgtct tctgctacaa aaatttatca aaatgtttgg ataggtaatt tttgggatta tcaaagtatg ttaaattatt tatctgagaa taaaccagtg gaaacatcaa aggaaaactt gaaagattat tattgtcaac catcaaactc aataactact agtactacta ctactactac taccaccacc accaccaata gtcaattatc attacctcag ccaaaagcta attggaaatt atttattcga tgtcatagtg aagcttcctt tcctgattta caagatttaa atcaattatt atttaaatat actatatcat cgcatgaaca atcagatgaa attcatcatt tggaattccc accactgggt tcaattggaa ttggtgattg taaaaaagaa aatttacaac tgataattaa tacttgtaaa ttgatttatt tatactcgtc aaccacaacc aaaaatcctt catctgggtt aaattcattg atttattgta ctgatggata tactgaactg tcattattag tattttgtta tttaatgtat tcattaaata tatcattaga tgaagctata ttagaattac atttaactta tggtagacca ttttatattt ttcctagtga tgtaattatt ttaaaaaaat tacaaccatt attaagaaag tttagtccca ccaccaagag tagcaacaat aacaattcaa tgaatcgaca aattgattgg gcaaatttag aaattctttc atcacaagaa attaatgaat tattattagg ttcaccaaaa gaatcctcac aacaaaatac cagattagga tttatttccc caaacgagga cgaggacgag gacgaggacg atgaagatga agatgaacaa gatattgata atgattcaag ttcaggatcc tcggattatt cttttaatga aattgattgg gttaatgaag ttgaaggatc aattccatca aaaatattac ctcatatata tttaggttca ttaaaacatg ccctgtgttt atcaatttta aataaattgg gtattcaaaa aatcatatca gtgggggaat cattaccttg gttaaatgga tatattttcc aacgtcataa tgatataact ataaaccaat ccaccgatgg taatattgaa acttatacca tcacccccaa aaagaaaacc aacttggttg cccattctca ccatattact tccgtggata cagtattaaa agttaataat ttagaagatg atggaattga tgaattaagt caaagattac cccaaatttt aaaatttata aatgatcaat atgaaattaa tcaaggtcaa gtgaaaattt taattcattg tcgagttggt gtaagtagaa gtgctaccgt tgtaattgct gaaatcatga atcgattaaa aattaattta ccaatggctt atctttatgt tagagtaaga cgattaaata taattattca accaaattta agattcatgt atgaattatt taaatgggaa gaacaaaaaa aactagccaa taatgagagg gataaggaag ttggttattt gagagaaatt gattggttta ttatgtgtcg agaaataact aaattaaata ctccatattt atga
AA Sequence
MMSITRTSTA TTTTTTASDI SQMEIKELEI EPRPKSTDNN SCSCSSSSSS SLIPSNTTKS NHIHKPIARR NIPIELKDDN IDGLNPTEKE NNMTKCIPNT KIDSSSSSTN STSTPLIPSD IHRACKRSSS SSNDLIYERD RFRARLKSFN DTQLHNNQHE PPPGTTTKME STSNSTINGI NELCEICDEI SVTVKTAKLN IDKNPLDNST MFYKLLPNYY PDKEDGMITI PVKQLNLDQV LEVFKWYFNS NLPNTKDMFP WLHGFHKYNF AQRSFFLHQQ QQLQQKLDNS STNTSNTNFQ DSMNHNELFT DYHLSRPDDI RFLMCINDES LPVNLHNTVK LTEILTKIDV SKSEIKEIIK KIWLNDKNGI ETETETETET DSSFIELLVT DCIKLNVLPI FLNLDPERGI SLRNFQIQVA KLSSCSDFII YGIDELKIQS ITRILWLAQR YERQQREIEI KESGKGNQQQ QTYNIFVLKN DLTQCYEKLP PSTTIMNTIQ SFAKYLKIDT SGLFYKPINQ YLLNDYNLPL YEKIETAKMS SATKIYQNVW IGNFWDYQSM LNYLSENKPV ETSKENLKDY YCQPSNSITT STTTTTTTTT TTNSQLSLPQ PKANWKLFIR CHSEASFPDL QDLNQLLFKY TISSHEQSDE IHHLEFPPLG SIGIGDCKKE NLQLIINTCK LIYLYSSTTT KNPSSGLNSL IYCTDGYTEL SLLVFCYLMY SLNISLDEAI LELHLTYGRP FYIFPSDVII LKKLQPLLRK FSPTTKSSNN NNSMNRQIDW ANLEILSSQE INELLLGSPK ESSQQNTRLG FISPNEDEDE DEDDEDEDEQ DIDNDSSSGS SDYSFNEIDW VNEVEGSIPS KILPHIYLGS LKHALCLSIL NKLGIQKIIS VGESLPWLNG YIFQRHNDIT INQSTDGNIE TYTITPKKKT NLVAHSHHIT SVDTVLKVNN LEDDGIDELS QRLPQILKFI NDQYEINQGQ VKILIHCRVG VSRSATVVIA EIMNRLKINL PMAYLYVRVR RLNIIIQPNL RFMYELFKWE EQKKLANNER DKEVGYLREI DWFIMCREIT KLNTPYL*