| Acc# | Gene | Locus | DB | Organism | Product | Score | E-value | Identities | Positives | Gaps |
|---|---|---|---|---|---|---|---|---|---|---|
| Q04119 | PPN1 | TrEMBL | Saccharomyces cerevisiae (Baker's yeast) | D9461.37P (ENDOPOLYPHOSPHATASE). | 483 | e-135 | 256/603 (42%) | 355/603 (58%) | 49/603 (8%) | |
| Q9P3S1 | B24P7.140 | TrEMBL | Neurospora crassa | Conserved hypothetical protein. | 312 | 8e-84 | 205/613 (33%) | 302/613 (49%) | 82/613 (13%) | |
| Q9C1W8 | SPBC713.07C | TrEMBL | Schizosaccharomyces pombe (Fission yeast) | Putative vacuolar polyphosphatase. | 284 | 2e-75 | 176/548 (32%) | 270/548 (49%) | 22/548 (4%) | |
| Q8WV13 | TrEMBL | Homo sapiens (Human) | Hypothetical protein. | 105 | 3e-21 | 82/279 (29%) | 126/279 (45%) | 14/279 (5%) | ||
| P70158 | ASML3A | AS3A_MOUSE | SP | Mus musculus (Mouse) | Acid sphingomyelinase-like phosphodiesterase 3a precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3a). | 100 | 7e-20 | 80/277 (28%) | 123/277 (44%) | 12/277 (4%) |
| Q96CB7 | TrEMBL | Homo sapiens (Human) | Similar to acid sphingomyelinase-like phosphodiesterase. | 98.6 | 2e-19 | 76/276 (27%) | 124/276 (44%) | 14/276 (5%) | ||
| Q92485 | ASML3B | AS3B_HUMAN | SP | Homo sapiens (Human) | Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3b). | 98.6 | 2e-19 | 76/276 (27%) | 124/276 (44%) | 14/276 (5%) |
| Q8MLP3 | CG3376 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG3376-PB. | 96.3 | 1e-18 | 82/285 (28%) | 118/285 (41%) | 24/285 (8%) | |
| Q9W188 | CG3376 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG3376 protein (LD42214P). | 96.3 | 1e-18 | 82/285 (28%) | 118/285 (41%) | 24/285 (8%) | |
| P58242 | ASML3B | AS3B_MOUSE | SP | Mus musculus (Mouse) | Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3b). | 92.0 | 2e-17 | 75/276 (27%) | 119/276 (43%) | 14/276 (5%) |
| Q23498 | ASM-2 | ASM2_CAEEL | SP | Caenorhabditis elegans | Sphingomyelin phosphodiesterase 2 precursor (EC 3.1.4.12) (Acid sphingomyelinase 2). | 77.0 | 8e-13 | 84/312 (26%) | 128/312 (41%) | 40/312 (12%) |
| Q04519 | SMPD1 | ASM_MOUSE | SP | Mus musculus (Mouse) | Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase). | 74.7 | 4e-12 | 76/284 (26%) | 121/284 (42%) | 23/284 (8%) |
| P17405 | SMPD1 | ASM_HUMAN | SP | Homo sapiens (Human) | Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase). | 74.3 | 5e-12 | 78/285 (27%) | 121/285 (42%) | 24/285 (8%) |
| Q8K011 | SMPD1 | TrEMBL | Mus musculus (Mouse) | Sphingomyelin phosphodiesterase 1, acid lysosomal. | 72.0 | 3e-11 | 76/284 (26%) | 120/284 (42%) | 23/284 (8%) | |
| Q8IQD3 | CG32052 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG32052-PA. | 67.8 | 5e-10 | 58/254 (22%) | 102/254 (40%) | 33/254 (12%) | |
| Q9UAY4 | W03G1.7 | ASM3_CAEEL | SP | Caenorhabditis elegans | Putative sphingomyelin phosphodiesterase W03G1.7 precursor (EC 3.1.4.12). | 65.5 | 2e-09 | 93/424 (21%) | 169/424 (39%) | 39/424 (9%) |
| Q9VA77 | CG15534 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG15534 protein. | 60.8 | 6e-08 | 89/383 (23%) | 148/383 (38%) | 34/383 (8%) | |
| Q10916 | ASM-1 | ASM1_CAEEL | SP | Caenorhabditis elegans | Sphingomyelin phosphodiesterase 1 precursor (EC 3.1.4.12) (Acid sphingomyelinase 1). | 60.5 | 8e-08 | 76/304 (25%) | 126/304 (41%) | 18/304 (5%) |
| Q9VA78 | CG15533 | TrEMBL | Drosophila melanogaster (Fruit fly) | CG15533 protein. | 50.8 | 6e-05 | 76/348 (21%) | 126/348 (36%) | 26/348 (7%) | |
| Q95T74 | CG3376 | TrEMBL | Drosophila melanogaster (Fruit fly) | GH14130p. | 50.1 | 1e-04 | 41/140 (29%) | 60/140 (42%) | 16/140 (11%) |
Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Metallophos Calcineurin-like phosphoesterase 10.9 0.22 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- Metallophos 1/1 94 319 .. 1 124 [] 10.9 0.22
CDS Sequence
ATGGAAAATA TTGGGCCAAA TAGACTGTCG GCCCGTCAAT ATCTATTGAT AACCTTCCTC ATTACATTTG TTGTTTCCAT TTCAACATAT CTATATTGTG CTGATTATGT ATCATACAAC ATTTGGAATT CAGTAACCTC AAAATCCAAC AAACCATACA TATCTATAAA GACATTAGAC TTGAATGATA CCCAAATCGA CGATCTTAAA CGTTTAGGGT TAACTCCAAA GAAATCAGTT GAGATAGTGA AACCAGATAA CAGCAAACAA ACCATCCATG GAAGATTCCT ACACATTACT GACTTCCACA TTGATCATCA TTACCAAAAA GGTAGTGATA TCGACAAAGT TTGTCACGGG GGTGAAGGAA AAGCTAGTAA ATATGGAGAT GCCATTTTGG GTTGTGATTC ACCTCCCATT CTTGTTGAAG AAACATTCAA ATGGATCACG GATAACCTTA TTGACAAAAT AGATTTTATT GTATACACCG GTGATTCAGC TAGACATGAT AATGATAGAG AATACCCTAG AACTAGACAA CACATTTTCA ATATGAACAA AGAGATAAGT GATAAGTTTG TCACATTGAC TTCAGAATCC GATGGCCAAC CTCTCATTTA TCCAGTGTCT AACAATGATA TTATGCCTCA CAATCTTATG GATACAGGAC CATCTTTGCA AACCAGAGAA TTATTCGAAG CTTGGAGACC ATTCATCCCT CAAGTTCAAA TGCATACATA TTTGATGGGT GCCTACTATT TTCAAGAAGT GATTCCTAAC CAATTGGCAG TATTGTCACT CAACACAATG TATTGGTTTG ATTCCAACCC TATGGTCGAT GATTGTGACA ACAAAGGTGA TCCTGGTTAT AAATTATTCG AATGGTTAGG GTATGTTTTG AAAGAAATGA GAGCCCGTAA TATGAAAGTA TGGCTTTGTG GTCATGTGCC CCCAAATGAA AAGAATTATG ACACCACATG TCTTCGTAAG TACATTGCTT GGACCCACGA ATATAGAGAT GTCATAGTAG GAGGATTATA TGGTCATATG AATTTAGATC ATTTCATCCC GTTAGATTCA GTACAAGCTT ATAAATCTAT CCAAAAAGAT TTCAAAGATG AATTTAAACA GAAAAGTGTT TTCAGTGTGG AAGACGAAGA TGACCTTGCA TTAGAAGATT CAAACTTATA CAAGGCTTTA GATGAAAATT TCAGTGACAA ATTTTTTAGA GTTACAGGTG GGGTTCCTAA TAACAAAGTG ACATACTTGG AAACGCTCAG AGAAGAATTA TATGCACCAT TGAAGGGAAA GAAGAAATCA GGGGAACATT TCGAAAGATA TTCAATAGCT CATGTTACTG CATCAATCAT TCCAACTTTC AACCCAGGTA TGAGGGTATG GGAGTATAAC ATTACTGATT TGGAAGATAA GCTACAACAA GTTAAATTTG AACCTTGGGA TAAGTTTTTC GCTGGTGTTG AACGAATGAT CGAAGTTCAG TCCAATTATG TCGATGAAAA GGACAACGAT GAAATGAATT GGCAAGAAAT GGATGATATA ACTATTGAAA GGAAGAAGAA ACATAAGAAA AAGAATAGGA AAAAGAAGAA GGATCATACA TTCCCTAAAC CAATGCCAGA GAATTTACCA CTTGGTCCTG CGTATATCGA ACAAACATTT ACTCCAGAAA GATATGTACA ATACTATGCC GATTTGGAAT CCATCAACAA AGGTAAAAAA GAATTTGATT ATGAAATAGA GTATAGCACT GATGATTCCT TATATGGATT AAAGGCATTA ACAGTTGAAG AATGGATCAA GTTTGGTAGA AAATTAGGTG AGCCAGTAAA AGATCTTAAA AATAATGTCA ATAAGGGGAA GAAAAAGAAG AACAATGGTA AAAAATATAA AAAATTACAA CAAATTTGGA ACGCTTATTT GAAACATGCA TTTATTAGTT CTGATTATGA ACATAAAGGA TACGGTTAA
AA Sequence
MENIGPNRLS ARQYLLITFL ITFVVSISTY LYCADYVSYN IWNSVTSKSN KPYISIKTLD LNDTQIDDLK RLGLTPKKSV EIVKPDNSKQ TIHGRFLHIT DFHIDHHYQK GSDIDKVCHG GEGKASKYGD AILGCDSPPI LVEETFKWIT DNLIDKIDFI VYTGDSARHD NDREYPRTRQ HIFNMNKEIS DKFVTLTSES DGQPLIYPVS NNDIMPHNLM DTGPSLQTRE LFEAWRPFIP QVQMHTYLMG AYYFQEVIPN QLAVLSLNTM YWFDSNPMVD DCDNKGDPGY KLFEWLGYVL KEMRARNMKV WLCGHVPPNE KNYDTTCLRK YIAWTHEYRD VIVGGLYGHM NLDHFIPLDS VQAYKSIQKD FKDEFKQKSV FSVEDEDDLA LEDSNLYKAL DENFSDKFFR VTGGVPNNKV TYLETLREEL YAPLKGKKKS GEHFERYSIA HVTASIIPTF NPGMRVWEYN ITDLEDKLQQ VKFEPWDKFF AGVERMIEVQ SNYVDEKDND EMNWQEMDDI TIERKKKHKK KNRKKKKDHT FPKPMPENLP LGPAYIEQTF TPERYVQYYA DLESINKGKK EFDYEIEYST DDSLYGLKAL TVEEWIKFGR KLGEPVKDLK NNVNKGKKKK NNGKKYKKLQ QIWNAYLKHA FISSDYEHKG YG*