BLASTX 2.2.6 [Apr-09-2003]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Candida_albicans_chr7-f2-273674-275722-8
         (2046 letters)

Database: sptrembl 
           1,070,300 sequences; 339,323,595 total letters

Searching.................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

P32829|MRE11|MR11_YEAST (SP: Saccharomyces cerevisiae (Baker's y...   516   e-145
Q8NK73|MHM11|Q8NK73 (TrEMBL: Magnaporthe grisea (Rice blast fung...   508   e-142
Q8J0S5|MRE11|Q8J0S5 (TrEMBL: Emericella nidulans (Aspergillus ni...   507   e-142
Q9C291|MUS-23|MR11_NEUCR (SP: Neurospora crassa) Double-strand b...   479   e-134
Q09683|RAD32|RA32_SCHPO (SP: Schizosaccharomyces pombe (Fission ...   479   e-134
Q9W6K1|MRE11|MR11_XENLA (SP: Xenopus laevis (African clawed frog...   386   e-106
Q9JIM0|MRE11A|MR11_RAT (SP: Rattus norvegicus (Rat)) Double-stra...   385   e-105
Q61216|MRE11A|MR11_MOUSE (SP: Mus musculus (Mouse)) Double-stran...   384   e-105
Q8BRV3||Q8BRV3 (TrEMBL: Mus musculus (Mouse)) Meiotic recombinat...   384   e-105
P49959|MRE11A|MR11_HUMAN (SP: Homo sapiens (Human)) Double-stran...   382   e-105
Q9IAM7|MRE11|MR11_CHICK (SP: Gallus gallus (Chicken)) Double-str...   368   e-100
Q9UVN9|MRE11|MR11_COPCI (SP: Coprinus cinereus (Inky cap fungus)...   358   1e-97
Q9XGM2|MRE11|MR11_ARATH (SP: Arabidopsis thaliana (Mouse-ear cre...   340   4e-92
Q9XYZ4|MRE11|Q9XYZ4 (TrEMBL: Drosophila melanogaster (Fruit fly)...   322   1e-86
Q9GZJ8|MRE11|Q9GZJ8 (TrEMBL: Bombyx mori (Silk moth)) Mre11.          315   1e-84
Q23255|MRE-11|MR11_CAEEL (SP: Caenorhabditis elegans) Double-str...   301   2e-80
Q8T8P1|MRE11|Q8T8P1 (TrEMBL: Trypanosoma brucei brucei) DNA repa...   249   9e-65
Q8WPP1|MRE11|Q8WPP1 (TrEMBL: Trypanosoma brucei) Mre11 protein.       249   9e-65
Q8SRV0|ECU05_1280|Q8SRV0 (TrEMBL: Encephalitozoon cuniculi) Doub...   231   3e-59
Q9BS79||Q9BS79 (TrEMBL: Homo sapiens (Human)) Hypothetical prote...   207   3e-52
Q86C23||Q86C23 (TrEMBL: Entamoeba histolytica) Mre11.                 182   1e-44
Q8I263|PFA0390W|Q8I263 (TrEMBL: Plasmodium falciparum (isolate 3...   141   3e-32
Q86C19||Q86C19 (TrEMBL: Giardia lamblia (Giardia intestinalis)) ...    61   6e-08
Q8TRL2|MA1163|Q8TRL2 (TrEMBL: Methanosarcina acetivorans) DNA re...    58   4e-07
Q8PUY5|MM2193|Q8PUY5 (TrEMBL: Methanosarcina mazei (Methanosarci...    55   3e-06
Q8NKQ0|MRE11|Q8NKQ0 (TrEMBL: Sulfolobus acidocaldarius) Mre11 pr...    55   3e-06
O29231|AF1031|O29231 (TrEMBL: Archaeoglobus fulgidus) DNA repair...    54   1e-05
Q97WG9|RAD32/MRE11|Q97WG9 (TrEMBL: Sulfolobus solfataricus) DNA ...    44   0.008
O26641|MTH541|O26641 (TrEMBL: Methanobacterium thermoautotrophic...    44   0.008
Q8I525|PFL1930W|Q8I525 (TrEMBL: Plasmodium falciparum (isolate 3...    42   0.022

>P32829|MRE11|MR11_YEAST (SP: Saccharomyces cerevisiae (Baker's
            yeast)) Double-strand break repair protein MRE11.
          Length = 692

 Score =  516 bits (1330), Expect = e-145
 Identities = 271/532 (50%), Positives = 353/532 (66%), Gaps = 11/532 (2%)
 Frame = +1

Query: 25   PGPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKP 204
            P PDTIR+L+TTDNHVG  ENDPI GDD+WKTF E+  +AK+ +VDM++Q GDLFH+NKP
Sbjct: 4    PDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKP 63

Query: 205  TKKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLN-NGFDEINYEDPNLNISIPVFAISG 381
            +KKS+Y V+K+LR  CMGD+PCELELLSDP+Q  + + F  +NYEDPN NISIPVF ISG
Sbjct: 64   SKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISG 123

Query: 382  NHDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDE 561
            NHDDA+G+SLL  +D+L  TGLIN+FGKV  ++ I V P+L QKG TKLALYG++ VRDE
Sbjct: 124  NHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDE 183

Query: 562  RLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEH 741
            RL R F+DGGV F+ P ++  +WFNL  +HQNH  HT T+ +PE FLP+FLD ++WGHEH
Sbjct: 184  RLFRTFKDGGVTFEVPTMREGEWFNLMCVHQNHTGHTNTAFLPEQFLPDFLDMVIWGHEH 243

Query: 742  ECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIK-GKDYSIEPVELKTVRP 918
            ECIP  VHNP   FDVLQ GSSVATSL E E   K +FIL+IK G+   + P+ L+T+R 
Sbjct: 244  ECIPNLVHNPIKNFDVLQPGSSVATSLCEAEAQPKYVFILDIKYGEAPKMTPIPLETIRT 303

Query: 919  FVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNN 1098
            F ++ I L     +     K     YL ++VE+ I  AN++   +           L+++
Sbjct: 304  FKMKSISLQDVPHL-RPHDKDATSKYLIEQVEEMIRDANEETKQK-----------LADD 351

Query: 1099 ATADPI-EKPLPLIRLRVEYSG--------GYEIENVTRFSNRFVGKIANVNDVVQFYKK 1251
               D + E P PLIRLRV+YS          Y++EN  RFSNRFVG++AN N+VVQFYKK
Sbjct: 352  GEGDMVAELPKPLIRLRVDYSAPSNTQSPIDYQVENPRRFSNRFVGRVANGNNVVQFYKK 411

Query: 1252 KTPTKSDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAV 1431
            ++P     K         D   E L  +   ELE+Q ++ D L + QLSL+PE  +N AV
Sbjct: 412  RSPVTRSKKSGINGTSISDRDVEKLFSESGGELEVQTLVNDLLNKMQLSLLPEVGLNEAV 471

Query: 1432 KKFVENDDKQALNQFINQEIKRETKMLLDIDIDENEFHGADEKHAKTAFKHV 1587
            KKFV+ D+K AL +FI+ EI  E  +L     +E      D +  K   K V
Sbjct: 472  KKFVDKDEKTALKEFISHEISNEVGIL---STNEEFLRTDDAEEMKALIKQV 520


>Q8NK73|MHM11|Q8NK73 (TrEMBL: Magnaporthe grisea (Rice blast fungus)
            (Pyricularia grisea)) Recombinational repair protein.
          Length = 566

 Score =  508 bits (1308), Expect = e-142
 Identities = 253/552 (45%), Positives = 353/552 (63%), Gaps = 12/552 (2%)
 Frame = +1

Query: 28   GPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPT 207
            GPD+IR+L+ TDNHVG  E DP+R DD+W+TFDE+  IA++KDVDM++ GGDLFH NKP+
Sbjct: 16   GPDSIRILVATDNHVGYNERDPVRRDDSWRTFDEVMQIAREKDVDMVLLGGDLFHDNKPS 75

Query: 208  KKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNH 387
            +KSMY V++SLR NC+G +PCELE L D A+     F  +NYEDP++NISIPVF+I GNH
Sbjct: 76   RKSMYQVIRSLRQNCLGMKPCELEFLCDAAEVFEGAFGHVNYEDPDINISIPVFSIHGNH 135

Query: 388  DDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERL 567
            DD +G+    +LD+L   GL+N FG+V   + I V P+LLQKG+TKLAL+G+SNVRDER+
Sbjct: 136  DDPSGDGHFCSLDLLQAAGLVNYFGRVPEADNIEVKPVLLQKGRTKLALFGISNVRDERM 195

Query: 568  HRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHEC 747
            HR FRD  VKF RPN   EDWFNL  +HQNH AHT TS +PE+FLP ++D ++WGHEHEC
Sbjct: 196  HRTFRDNHVKFFRPNQAKEDWFNLLTVHQNHHAHTATSYLPENFLPEWMDLVVWGHEHEC 255

Query: 748  IPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFVL 927
            +  P+ NPET F V+Q GSSVATSL  GE   K + +L + GK + +E V LKTVRPFV 
Sbjct: 256  LIDPIENPETRFHVMQPGSSVATSLVPGEAKTKHVAVLTVTGKQFQVEKVPLKTVRPFVT 315

Query: 928  REIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNATA 1107
            +EI+L +   +   A   D  A +T+++   ++   K+   Q +      +  L  N+T 
Sbjct: 316  KEIVLSQEPKLKKLAKDKDNRAKVTEQLISIVQDMIKEAQGQWL-----KLQALEGNSTP 370

Query: 1108 DPIEKPLPLIRLRVEYS----GGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDN 1275
             P E PLPLIRL+VE+S    G +++EN  RFSNRF GK+AN NDV+ FY+ K P    N
Sbjct: 371  GPAEMPLPLIRLKVEHSAPDGGEFKLENPQRFSNRFAGKVANTNDVIYFYQDKKPLAIPN 430

Query: 1276 KLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFVENDD 1455
             +      D+              L++++++ D+L    + ++P+ +M  AV +FV  DD
Sbjct: 431  VMAEDGNIDI--------------LKVEELVSDYLAAQSVKILPQKQMGDAVNQFVSKDD 476

Query: 1456 KQALNQFINQEIKRETKMLLDIDIDENEFHGADEKHAKTAFKHVLLQL--------KNIN 1611
            K+A+   +   +  + K ++ ++ DEN+     EK     FK    +         + IN
Sbjct: 477  KRAMEDVVIDSLTTQVKGMMALETDENDV----EKEMAALFKKQASKFEAGHGSKKRRIN 532

Query: 1612 GPINIDYEPEIE 1647
             P   DY+ +IE
Sbjct: 533  VPQPDDYDSDIE 544


>Q8J0S5|MRE11|Q8J0S5 (TrEMBL: Emericella nidulans (Aspergillus
            nidulans)) Meiotic recombination protein.
          Length = 636

 Score =  507 bits (1306), Expect = e-142
 Identities = 253/534 (47%), Positives = 356/534 (66%), Gaps = 9/534 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            +TIR+L++TDNHVG  E DPIRGDD+WK+F E+  +AK  DVDM++  GDLFH NKP++K
Sbjct: 8    ETIRILVSTDNHVGYNERDPIRGDDSWKSFHEVMCLAKQHDVDMVLLAGDLFHENKPSRK 67

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDD 393
            SMY VM+S+R NC+GD+PCEL+LLSD +++    F+ +NYED ++N+ IP+F+I GNHDD
Sbjct: 68   SMYQVMRSIRMNCLGDKPCELQLLSDASENFQGAFNHVNYEDLDINVGIPIFSIHGNHDD 127

Query: 394  ATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHR 573
             +GE  L ALD+L V+GL+N +G+   ++ I + P+LLQKG+TKLALYGMSNVRDERL R
Sbjct: 128  PSGEGHLAALDILQVSGLLNYYGRTPESDNIQLKPVLLQKGRTKLALYGMSNVRDERLFR 187

Query: 574  LFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHECIP 753
             FRDG VKF RP++Q EDW+NL  +HQNH A+T T  +PE+FLP FLD ++WGHEHEC+ 
Sbjct: 188  TFRDGKVKFFRPSVQKEDWYNLICVHQNHHAYTETGYLPENFLPEFLDLVIWGHEHECLI 247

Query: 754  YPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFVLRE 933
             P  NPE  F V+Q GSSVATSL  GE   K + IL+IKGK+   +P+ LK+VRPF +RE
Sbjct: 248  NPRINPEMKFRVMQPGSSVATSLVPGEAVPKHVAILSIKGKEMKCKPIRLKSVRPFAMRE 307

Query: 934  IILLK----TDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNA 1101
            I+L +      L     ++ +V  +L   VE+ IE A  ++     L+  +         
Sbjct: 308  IVLSEERGAQKLARKENNRTEVTRFLMTIVEELIEEAKAEWLE---LHRPQRREGEEEEE 364

Query: 1102 TADPIEKPLPLIRLRVEYS----GGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKS 1269
              + +E PLPL+RLRVE S    G Y+ EN  RFSNRFVGK+ANVNDVVQFY+KK     
Sbjct: 365  DDEELEVPLPLVRLRVETSTPEGGSYDCENPQRFSNRFVGKVANVNDVVQFYRKK----- 419

Query: 1270 DNKLTRKTKYDVDLIEENLHHKKTTE-LELQDIIRDFLQQTQLSLVPETEMNHAVKKFVE 1446
              K     K + +L E  L    T + ++++ ++R+FL Q  LS++P+     AV +F++
Sbjct: 420  --KTATSRKKENELDEAALSRLSTLDTVQVEQLVREFLSQQSLSILPQNSFGDAVSQFID 477

Query: 1447 NDDKQALNQFINQEIKRETKMLLDIDIDENEFHGADEKHAKTAFKHVLLQLKNI 1608
             DDK A+  F+N+ ++ + K LL +D D +      +   + A +    Q++ +
Sbjct: 478  KDDKHAMEMFVNESLEGQIKHLLSLDRDSDAEDDESQSSLQKAMERYRTQMEEM 531


>Q9C291|MUS-23|MR11_NEUCR (SP: Neurospora crassa) Double-strand break
            repair protein mus-23 (Recombinational repair protein
            mus-23).
          Length = 760

 Score =  479 bits (1234), Expect = e-134
 Identities = 242/510 (47%), Positives = 337/510 (66%), Gaps = 7/510 (1%)
 Frame = +1

Query: 25   PGPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKP 204
            P  DTIR+L++TDNHVG  E  P+R DD+W+TFDEI  IAK +DVDM++ GGDLFH NKP
Sbjct: 25   PEADTIRILVSTDNHVGYAERHPVRKDDSWRTFDEIMQIAKKQDVDMVLLGGDLFHENKP 84

Query: 205  TKKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGN 384
            ++KSMY VM+SLR +C+G +PCELE LSD A+     F  +NYEDP++N++IPVF+I GN
Sbjct: 85   SRKSMYQVMRSLRKHCLGMKPCELEFLSDAAEVFEGAFPFVNYEDPDINVAIPVFSIHGN 144

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD +G+    +LD+L   GL+N FG+V   + I V PILLQKG+TK+ALYG+SNVRDER
Sbjct: 145  HDDPSGDGHYCSLDLLQAAGLVNYFGRVPEADNIHVKPILLQKGRTKMALYGLSNVRDER 204

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            +HR FRD  V+F RPN Q  DWFNL  +HQNH AHT TS + E+ LP+F+D ++WGHEHE
Sbjct: 205  MHRTFRDNKVRFYRPNQQKNDWFNLLALHQNHYAHTRTSYVAENMLPDFMDLVIWGHEHE 264

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C+  PV NPET F V+Q GSSVATSL  GE   K + ILNI G+ + ++ + LKTVRPFV
Sbjct: 265  CLIDPVRNPETGFHVMQPGSSVATSLVPGEAVPKHVAILNITGRKFEVDKIPLKTVRPFV 324

Query: 925  LREIILLKTDLIPG---AASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
             REI+L       G     ++ ++   L   V + IE AN ++         RA+ +  +
Sbjct: 325  TREIVLASDKRFKGLDKQNNRHEITKRLMVIVNEMIEEANAEW---------RAV-HAED 374

Query: 1096 NATADPIEKPLPLIRLRVEYS----GGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPT 1263
            +   + +E PLPL+RL+V+Y+      YE+EN  RFSNRF GK+AN NDVV+F+   T  
Sbjct: 375  DDMDEDMEPPLPLVRLKVDYTAPDGARYEVENPHRFSNRFTGKVANHNDVVRFH-CNTKG 433

Query: 1264 KSDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFV 1443
            K +       + D+  I E+        +++ +++++F  Q  L ++P+   + AV +FV
Sbjct: 434  KKNVATAPGVREDIAEILES-----ADTIKVDNLVQEFFAQQSLKILPQAPFSDAVNQFV 488

Query: 1444 ENDDKQALNQFINQEIKRETKMLLDIDIDE 1533
              DDK A+  F+ + +  + K LL +D D+
Sbjct: 489  SKDDKHAVEMFVIESLSTQVKELLQLDDDK 518


>Q09683|RAD32|RA32_SCHPO (SP: Schizosaccharomyces pombe (Fission
            yeast)) DNA repair protein rad32.
          Length = 649

 Score =  479 bits (1233), Expect = e-134
 Identities = 238/502 (47%), Positives = 343/502 (68%), Gaps = 2/502 (0%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            +TIR+L+++D HVG  E DP+RG+D++ +F+EI  IA+++DVDMI+ GGD+FH NKP++K
Sbjct: 16   NTIRILISSDPHVGYGEKDPVRGNDSFVSFNEILEIARERDVDMILLGGDIFHDNKPSRK 75

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNN-GFDEINYEDPNLNISIPVFAISGNHD 390
            ++Y  ++SLR NC+GD+PCELELLSD + +  +     INY DPN+N++IPVF+I GNHD
Sbjct: 76   ALYQALRSLRLNCLGDKPCELELLSDTSLTTGDTAVCNINYLDPNINVAIPVFSIHGNHD 135

Query: 391  DATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLH 570
            D +G+    ALD+L VTGL+N FG+V   + I VSPILLQKG TKLALYG+SNVRDERL+
Sbjct: 136  DPSGDGRYSALDILQVTGLVNYFGRVPENDNIVVSPILLQKGFTKLALYGISNVRDERLY 195

Query: 571  RLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHECI 750
              FR+  VKF RP++  ++WFNL  +HQNH+AHT TS +PESF+ +F DF+LWGHEHEC+
Sbjct: 196  HSFRENKVKFLRPDLYRDEWFNLLTVHQNHSAHTPTSYLPESFIQDFYDFVLWGHEHECL 255

Query: 751  PYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFVLR 930
                +NP   F V+Q GS++ATSL+ GE A K   ILNI GKD+ +E + L+TVRPF+++
Sbjct: 256  IDGSYNPTQKFTVVQPGSTIATSLSPGETAPKHCGILNITGKDFHLEKIRLRTVRPFIMK 315

Query: 931  EIILLKTDLIPG-AASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNATA 1107
            +IIL +   IP    +K +V+ YL  +VE++I  AN Q+       +   +  + N    
Sbjct: 316  DIILSEVSSIPPMVENKKEVLTYLISKVEEAITEANAQW-----YEAQGTVPVVENE--- 367

Query: 1108 DPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDNKLTR 1287
               + PLPLIRLRV+Y+GGY+ EN  RFSNRFVG++AN  DVVQFY KK  T+S      
Sbjct: 368  ---KPPLPLIRLRVDYTGGYQTENPQRFSNRFVGRVANATDVVQFYLKKKYTRS------ 418

Query: 1288 KTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFVENDDKQAL 1467
              K +  L    +   K   L ++ ++ ++L+  +L  +PE  +  AV  FVE DD+ A+
Sbjct: 419  --KRNDGLYTSAVEDIKINSLRVESLVNEYLKTNRLECLPEDSLGEAVVNFVEKDDRDAI 476

Query: 1468 NQFINQEIKRETKMLLDIDIDE 1533
             + +  ++ ++  +L+   + E
Sbjct: 477  KECVETQLNKQINLLVKKRVTE 498


>Q9W6K1|MRE11|MR11_XENLA (SP: Xenopus laevis (African clawed frog))
            Double-strand break repair protein MRE11.
          Length = 711

 Score =  386 bits (992), Expect = e-106
 Identities = 203/513 (39%), Positives = 311/513 (60%), Gaps = 11/513 (2%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT ++L+ TD H+G  E D +RG+D++  FDEI  +A+D +VD ++ GGDLFH NKP+++
Sbjct: 12   DTFKILVATDIHLGFMEKDAVRGNDSFVAFDEILRLAQDNEVDFLLLGGDLFHDNKPSRR 71

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
            +++  ++ LR  CMGDRP E E+LSD  QS+N G+ +   +NY+D NLNIS+PVF++ GN
Sbjct: 72   TLHICLEQLRKYCMGDRPIEFEVLSD--QSVNFGYSKFPWVNYQDNNLNISLPVFSVHGN 129

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD TG   L ALD+L+  GL+N+FG+  + E I +SP+LLQKG +K+ALYG+ ++ DER
Sbjct: 130  HDDPTGADALCALDILSSAGLVNHFGRATSVEKIDISPVLLQKGHSKIALYGLGSIPDER 189

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            L+R+F +  V   RP      WFNLFVIHQN + H  T+ IPE FL  FLD ++WGHEHE
Sbjct: 190  LYRMFVNKQVMMLRPREDESSWFNLFVIHQNRSKHGPTNYIPEQFLDEFLDLVIWGHEHE 249

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C   P  N +  F V Q GSSVATSL+ GE   K + +L IKGK  +++ + L+TVR F 
Sbjct: 250  CKIAPTRNEQQLFYVSQPGSSVATSLSPGEAEKKHVGLLRIKGKKMNMQKIPLQTVRQFF 309

Query: 925  LREIILLKTDLI---PGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            + +++L     I          ++  +  ++VE  ++ A ++                  
Sbjct: 310  IEDLVLSDYPDIFNPDNPRVTQEIETFCIEKVEAMLDTAERE------------------ 351

Query: 1096 NATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYK-KKTPTKSD 1272
                +P +   PLIRLRV+Y+GG+E  N  RFS +FV + AN  D++ F++ K+   K D
Sbjct: 352  -RLGNPRQPDKPLIRLRVDYTGGFEPFNTLRFSQKFVDRTANPKDIIHFFRHKEQKDKKD 410

Query: 1273 NKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFL----QQTQLSLVPETEMNHAVKKF 1440
            +      K D   + E       T L ++D+++++     +  QLSL+ E  M  AV++F
Sbjct: 411  SITINFGKIDSKPLLEG------TTLRVEDLVKEYFKTAEKNVQLSLLTERGMGEAVQEF 464

Query: 1441 VENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            V+ ++K AL + +  ++++  + L +  ID  E
Sbjct: 465  VDKEEKDALEELVKFQLEKTQRFLKERHIDAEE 497


>Q9JIM0|MRE11A|MR11_RAT (SP: Rattus norvegicus (Rat)) Double-strand
            break repair protein MRE11A (MRE11 homolog 1).
          Length = 706

 Score =  385 bits (988), Expect = e-105
 Identities = 201/512 (39%), Positives = 311/512 (60%), Gaps = 10/512 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT ++L+ TD H+G  E D +RG+D + TFDEI  +A + +VD I+ GGDLFH NKP++K
Sbjct: 11   DTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRK 70

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
            +++  ++ LR  CMGDRP + E++SD  QS+N GF +   +NY D NLNISIPVF+I GN
Sbjct: 71   TLHSCLELLRKYCMGDRPVQFEIISD--QSVNFGFSKFPWVNYRDGNLNISIPVFSIHGN 128

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD TG   L ALDVL+  G +N+FG+  + E + +SP+LLQKG TKLALYG+ ++ DER
Sbjct: 129  HDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDER 188

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            L+R+F +  V   RP      WFNLFVIHQN + H  T+ IPE FL +F+D ++WGHEHE
Sbjct: 189  LYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHE 248

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C   P  N +  F V Q GSSV T+L+ GE   K + +L +KG+  +++ + L+TVR F 
Sbjct: 249  CKIGPTRNEQQLFYVSQPGSSVVTALSPGETVKKHVGLLRVKGRKMNMQKLPLRTVRQFF 308

Query: 925  LREIILLKTDLI--PGAASKADVI-AYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            + +++L     +  P        I ++  +++E+ ++ A ++                  
Sbjct: 309  MEDVVLANHPSLFNPDNPKVTQAIQSFCLEKIEEMLDSAERE------------------ 350

Query: 1096 NATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDN 1275
                +P +   PLIRLRV+YSGG+E  NV RFS +FV ++AN  DV+ F++ +   +   
Sbjct: 351  -RLGNPQQPEKPLIRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHR---EQKG 406

Query: 1276 KLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQ----QTQLSLVPETEMNHAVKKFV 1443
            K   +  +   +I+      + T L ++D+++ + Q      QLSL+ E  M  AV++FV
Sbjct: 407  KTGEEINFGKLIIKP---ASEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFV 463

Query: 1444 ENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            + ++K A+ + +  ++++  + L +  ID  E
Sbjct: 464  DKEEKDAIEELVKYQLEKTQRFLKERHIDALE 495


>Q61216|MRE11A|MR11_MOUSE (SP: Mus musculus (Mouse)) Double-strand
            break repair protein MRE11A (MRE11 homolog 1) (MmMRE11A).
          Length = 706

 Score =  384 bits (987), Expect = e-105
 Identities = 204/512 (39%), Positives = 313/512 (61%), Gaps = 10/512 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT ++L+ TD H+G  E D +RG+D + TFDEI  +A + +VD I+ GGDLFH NKP++K
Sbjct: 11   DTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRK 70

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
            +++  ++ LR  CMGDRP + E++SD  QS+N GF +   +NY+D NLNISIPVF+I GN
Sbjct: 71   TLHSCLELLRKYCMGDRPVQFEVISD--QSVNFGFSKFPWVNYQDGNLNISIPVFSIHGN 128

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD TG   L ALDVL+  G +N+FG+  + E + +SP+LLQKG TKLALYG+ ++ DER
Sbjct: 129  HDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDER 188

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            L+R+F +  V   RP      WFNLFVIHQN + H  T+ IPE FL +F+D ++WGHEHE
Sbjct: 189  LYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDLVIWGHEHE 248

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C   P+ N +  F V Q GSSV TSL+ GE   K + +L IKG+  +++ + L+TVR F 
Sbjct: 249  CKIGPIKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKLPLRTVRRFF 308

Query: 925  LREIILLKTDLI--PGAASKADVI-AYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            + +++L     +  P        I ++  +++E+ ++ A ++                  
Sbjct: 309  IEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLDSAERE------------------ 350

Query: 1096 NATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDN 1275
                +P +   PLIRLRV+YSGG+E  NV RFS +FV ++AN  DV+ F++ +   +   
Sbjct: 351  -RLGNPQQPGKPLIRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHR---EQKG 406

Query: 1276 KLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQ----QTQLSLVPETEMNHAVKKFV 1443
            K   +  + + LI +      T  L ++D+++ + Q      QLSL+ E  M  AV++FV
Sbjct: 407  KTGEEINFGM-LITKPASEGAT--LRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFV 463

Query: 1444 ENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            + ++K A+ + +  ++++  + L +  ID  E
Sbjct: 464  DKEEKDAIEELVKYQLEKTQRFLKERHIDALE 495


>Q8BRV3||Q8BRV3 (TrEMBL: Mus musculus (Mouse)) Meiotic recombination
            11 homolog A (Fragment).
          Length = 513

 Score =  384 bits (987), Expect = e-105
 Identities = 204/512 (39%), Positives = 313/512 (61%), Gaps = 10/512 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT ++L+ TD H+G  E D +RG+D + TFDEI  +A + +VD I+ GGDLFH NKP++K
Sbjct: 11   DTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRK 70

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
            +++  ++ LR  CMGDRP + E++SD  QS+N GF +   +NY+D NLNISIPVF+I GN
Sbjct: 71   TLHSCLELLRKYCMGDRPVQFEVISD--QSVNFGFSKFPWVNYQDGNLNISIPVFSIHGN 128

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD TG   L ALDVL+  G +N+FG+  + E + +SP+LLQKG TKLALYG+ ++ DER
Sbjct: 129  HDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDER 188

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            L+R+F +  V   RP      WFNLFVIHQN + H  T+ IPE FL +F+D ++WGHEHE
Sbjct: 189  LYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDLVIWGHEHE 248

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C   P+ N +  F V Q GSSV TSL+ GE   K + +L IKG+  +++ + L+TVR F 
Sbjct: 249  CKIGPIKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKLPLRTVRRFF 308

Query: 925  LREIILLKTDLI--PGAASKADVI-AYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            + +++L     +  P        I ++  +++E+ ++ A ++                  
Sbjct: 309  IEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLDSAERE------------------ 350

Query: 1096 NATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDN 1275
                +P +   PLIRLRV+YSGG+E  NV RFS +FV ++AN  DV+ F++ +   +   
Sbjct: 351  -RLGNPQQPGKPLIRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHR---EQKG 406

Query: 1276 KLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQ----QTQLSLVPETEMNHAVKKFV 1443
            K   +  + + LI +      T  L ++D+++ + Q      QLSL+ E  M  AV++FV
Sbjct: 407  KTGEEINFGM-LITKPASEGAT--LRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFV 463

Query: 1444 ENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            + ++K A+ + +  ++++  + L +  ID  E
Sbjct: 464  DKEEKDAIEELVKYQLEKTQRFLKERHIDALE 495


>P49959|MRE11A|MR11_HUMAN (SP: Homo sapiens (Human)) Double-strand
            break repair protein MRE11A (MRE11 homolog 1).
          Length = 708

 Score =  382 bits (981), Expect = e-105
 Identities = 200/509 (39%), Positives = 309/509 (60%), Gaps = 7/509 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            +T ++L+ TD H+G  E D +RG+D + T DEI  +A++ +VD I+ GGDLFH NKP++K
Sbjct: 11   NTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRK 70

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
            +++  ++ LR  CMGDRP + E+LSD  QS+N GF +   +NY+D NLNISIPVF+I GN
Sbjct: 71   TLHTCLELLRKYCMGDRPVQFEILSD--QSVNFGFSKFPWVNYQDGNLNISIPVFSIHGN 128

Query: 385  HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
            HDD TG   L ALD+L+  G +N+FG+  + E I +SP+LLQKG TK+ALYG+ ++ DER
Sbjct: 129  HDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDER 188

Query: 565  LHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHE 744
            L+R+F +  V   RP      WFNLFVIHQN + H  T+ IPE FL +F+D ++WGHEHE
Sbjct: 189  LYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHE 248

Query: 745  CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
            C   P  N +  F + Q GSSV TSL+ GE   K + +L IKG+  ++  + L TVR F 
Sbjct: 249  CKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFF 308

Query: 925  LREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNAT 1104
            + +I+L         A+  D+      +V ++I+     F  + I      + N      
Sbjct: 309  MEDIVL---------ANHPDIFNPDNPKVTQAIQ----SFCLEKI---EEMLENAERERL 352

Query: 1105 ADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDNKLT 1284
             +  +   PL+RLRV+YSGG+E  +V RFS +FV ++AN  D++ F++ +       +  
Sbjct: 353  GNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFRHR-------EQK 405

Query: 1285 RKTKYDVDLIEENLHHKKTTELELQDIIRDFLQ----QTQLSLVPETEMNHAVKKFVEND 1452
             KT  +++  +      + T L ++D+++ + Q      QLSL+ E  M  AV++FV+ +
Sbjct: 406  EKTGEEINFGKLITKPSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKE 465

Query: 1453 DKQALNQFINQEIKRETKMLLDIDIDENE 1539
            +K A+ + +  ++++  + L +  ID  E
Sbjct: 466  EKDAIEELVKYQLEKTQRFLKERHIDALE 494


>Q9IAM7|MRE11|MR11_CHICK (SP: Gallus gallus (Chicken)) Double-strand
            break repair protein MRE11.
          Length = 700

 Score =  368 bits (944), Expect = e-100
 Identities = 196/515 (38%), Positives = 307/515 (59%), Gaps = 8/515 (1%)
 Frame = +1

Query: 19   IEPGPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHIN 198
            ++   DT ++L+ TD H+G  E D +RG+D + TF+EI   A+  +VD I+ GGDLFH N
Sbjct: 6    LQDDEDTFKILIATDIHLGYLEKDAVRGNDTFVTFNEILEHAQKNEVDFILLGGDLFHEN 65

Query: 199  KPTKKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLN-NGFDEINYEDPNLNISIPVFAI 375
            KP++K+++  ++SLR  CMGDRP   E+LSD A +   + F  +NY+D NLNI +P+F+I
Sbjct: 66   KPSRKTIHTCLESLRKYCMGDRPVSFEVLSDQAVNFQLSKFPWVNYQDENLNIFMPIFSI 125

Query: 376  SGNHDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVR 555
             GNHDD TG   L ALD+L+  GL+N+FG+  + E I +SPILL+KG+TK+ALYG+  + 
Sbjct: 126  HGNHDDPTGVDALCALDILSCAGLLNHFGRSTSVEKIDISPILLRKGRTKIALYGLGAIP 185

Query: 556  DERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGH 735
            DERL+R+F +  V   RP    + WFN+FVIHQN + H  T+ IPE FL +F++  +WGH
Sbjct: 186  DERLYRMFVNKQVTMLRPKEDEDSWFNMFVIHQNRSKHGATNYIPEQFLDDFINLAVWGH 245

Query: 736  EHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVR 915
            EHEC   P  N +  F V Q GSSV TSL+ GE   K I +L +KGK   ++ + L+TVR
Sbjct: 246  EHECKITPAQNEQQHFYVTQPGSSVVTSLSPGEAVKKHIGLLRVKGKKMKMQRIALETVR 305

Query: 916  PFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
             F + +++L            AD       +  K + +A + F  + +      + N   
Sbjct: 306  TFYMEDVVL------------ADHPELFNPDNPK-VTQAIQAFCMEKV---EMMLDNAER 349

Query: 1096 NATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDN 1275
                +P +   PLI LRV+Y+GG+E   V RFS +++ ++AN  D++ F++ +       
Sbjct: 350  ERLGNPRQPQKPLIILRVDYTGGFEPFIVHRFSQKYMDRVANPKDIIHFFRHR------- 402

Query: 1276 KLTRKTKYDVDLIEENLHHKKTTE---LELQDIIRDFLQ----QTQLSLVPETEMNHAVK 1434
               +K K D D+    L  +  +E   L ++D+++ + Q    + QLSL+ E  M  AV+
Sbjct: 403  --EQKEKNDNDINFGKLLSRPASEEVTLRVEDLVKQYFQTAEKKVQLSLLTERRMGEAVQ 460

Query: 1435 KFVENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            +FV+ ++K A+ + +  ++++  + L +  ID  E
Sbjct: 461  EFVDKEEKDAIEELVKFQLEKTQRFLKERHIDAEE 495


>Q9UVN9|MRE11|MR11_COPCI (SP: Coprinus cinereus (Inky cap fungus))
            Double-strand break repair protein MRE11.
          Length = 731

 Score =  358 bits (920), Expect = 1e-97
 Identities = 202/535 (37%), Positives = 304/535 (56%), Gaps = 23/535 (4%)
 Frame = +1

Query: 4    PLVERIEPGPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGD 183
            P +E  +P  DTI++LL TDNH+G  E DPIRG D+  TF EI  +A   +VD I+  GD
Sbjct: 12   PNIETADP-EDTIKILLATDNHIGYLERDPIRGQDSINTFREILQLAVKNEVDFILLAGD 70

Query: 184  LFHINKPTKKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFD--EINYEDPNLNIS 357
            LFH NKP++  +Y  +  LR   +GD+P ++ELLSDP +    GF    INYEDPN NIS
Sbjct: 71   LFHENKPSRDCLYQTLALLREYTLGDKPIQVELLSDPDEGKAAGFSFPAINYEDPNFNIS 130

Query: 358  IPVFAISGNHDDATGESL---LLALDVLAVTGLINNFGKVK--------NTEAITVSPIL 504
            IPVF+I GNHDD  G  +   L ALDVL+V+GL+N  GK           T  I V P+L
Sbjct: 131  IPVFSIHGNHDDPQGPGVNGALCALDVLSVSGLLNYMGKFDLPTSDADAATTGIAVRPVL 190

Query: 505  LQKGQTKLALYGMSNVRDERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSS 684
            L+KG TKL +YG+ NV+D+R+H   R   V+   P    ++WFN+ ++HQN   H     
Sbjct: 191  LRKGSTKLGMYGVGNVKDQRMHFELRSNRVRMYMPK-DKDEWFNILLVHQNRVKHGPQEY 249

Query: 685  IPESFLPNFLDFILWGHEHEC--IPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFI 858
            +PE    + +D ++WGHEH+C  IP PV      + + Q GSSVATSLA+GE  +K + +
Sbjct: 250  VPEGMFDDSVDLVVWGHEHDCRIIPEPVAG--KNYYITQPGSSVATSLADGEAIEKHVAL 307

Query: 859  LNIKGKDYSIEPVELKTVRPFVLREIILLKTDLIPG--AASKADVIAYLTDEVEKSIERA 1032
            L IKGK++ + P+ L+TVRPFV+ E++L       G     + ++  YL  +V   I++A
Sbjct: 308  LEIKGKEFQLTPIPLRTVRPFVISEVVLEDAAEEEGLDVNDQMEITKYLKQKVNDLIDQA 367

Query: 1033 NKQFSSQNILNSNRAITNLSNNATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGK 1212
               +  +N           S  A  + I   LPL+RL+V+ +   +  N  RF   F G+
Sbjct: 368  QALWEERNA---------RSIEAGDEEIPPMLPLVRLKVDTTNVTQTSNPIRFGQEFQGR 418

Query: 1213 IANVNDVVQFYKKKTPTKSDNKLTRKTKYDVDLIEENLH------HKKTTELELQDIIRD 1374
            +AN  D++ F++ K   K         K D+D  E ++        +K  ++ ++ ++R+
Sbjct: 419  VANPRDLLVFHRSKKAGKRG-----AGKVDIDQPELSIDDPDLTVSEKLAKVRVKTLVRE 473

Query: 1375 FLQQTQLSLVPETEMNHAVKKFVENDDKQALNQFINQEIKRETKMLLDIDIDENE 1539
            +L   +L L+ E  M+ A++ FVE DD  A+   +N+ +K   K +   ++DE++
Sbjct: 474  YLAAQELQLLGENGMSDAIQMFVEKDDIHAIQTHVNKSLKTMLKNIKSDEVDEDD 528


>Q9XGM2|MRE11|MR11_ARATH (SP: Arabidopsis thaliana (Mouse-ear cress))
            Double-strand break repair protein MRE11.
          Length = 720

 Score =  340 bits (872), Expect = 4e-92
 Identities = 189/517 (36%), Positives = 296/517 (57%), Gaps = 10/517 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT+RVL+ TD H+G  E D IR  D++K F+EI +IA++K VD ++ GGDLFH NKP++ 
Sbjct: 8    DTLRVLVATDCHLGYMEKDEIRRHDSFKAFEEICSIAEEKQVDFLLLGGDLFHENKPSRT 67

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDD 393
            ++   ++ LR +C+ D+P + +++SD   +  N F ++NYEDP+ N+ +PVF+I GNHDD
Sbjct: 68   TLVKAIEILRRHCLNDKPVQFQVVSDQTVNFQNAFGQVNYEDPHFNVGLPVFSIHGNHDD 127

Query: 394  ATGESLLLALDVLAVTGLINNFGKV----KNTEAITVSPILLQKGQTKLALYGMSNVRDE 561
              G   L A+D+L+   L+N FGK+         IT+ PIL++KG T +ALYG+ N+RDE
Sbjct: 128  PAGVDNLSAIDILSACNLVNYFGKMVLGGSGVGQITLYPILMKKGSTTVALYGLGNIRDE 187

Query: 562  RLHRLFR-DGGVKFQRPNIQ----TEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFIL 726
            RL+R+F+    V++ RP +Q      DWFN+ V+HQN       ++I E FLP FLDFI+
Sbjct: 188  RLNRMFQTPHAVQWMRPEVQEGCDVSDWFNILVLHQNRVKSNPKNAISEHFLPRFLDFIV 247

Query: 727  WGHEHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELK 906
            WGHEHEC+  P       F + Q GSSVATSL +GE   K + +L IKG  Y    + L 
Sbjct: 248  WGHEHECLIDPQEVSGMGFHITQPGSSVATSLIDGESKPKHVLLLEIKGNQYRPTKIPLT 307

Query: 907  TVRPFVLREIILL-KTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAIT 1083
            +VRPF   EI+L  ++D+ P    +  ++ +L   V   IE+A+K+  +++         
Sbjct: 308  SVRPFEYTEIVLKDESDIDPN--DQNSILEHLDKVVRNLIEKASKKAVNRS--------- 356

Query: 1084 NLSNNATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPT 1263
                       E  LPL+R++V+YSG   I N  RF  ++VGK+AN  D++ F K     
Sbjct: 357  -----------EIKLPLVRIKVDYSGFMTI-NPQRFGQKYVGKVANPQDILIFSKASKKG 404

Query: 1264 KSDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFV 1443
            +S+  +            E L  ++  +  ++ ++ +     ++ ++P  +++ A+  FV
Sbjct: 405  RSEANIDD---------SERLRPEELNQQNIEALVAE--SNLKMEILPVNDLDVALHNFV 453

Query: 1444 ENDDKQALNQFINQEIKRETKMLLDIDIDENEFHGAD 1554
              DDK A    +   + +ET+  L  D D  +F   D
Sbjct: 454  NKDDKLAFYSCVQYNL-QETRGKLAKDSDAKKFEEDD 489


>Q9XYZ4|MRE11|Q9XYZ4 (TrEMBL: Drosophila melanogaster (Fruit fly))
            MRE11 protein.
          Length = 620

 Score =  322 bits (824), Expect = 1e-86
 Identities = 179/432 (41%), Positives = 259/432 (59%), Gaps = 18/432 (4%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            + IR+L+ TDNH+G  E D +RG+D++  F+EI  +A  +DVDMI+ GGDLFH   P++ 
Sbjct: 13   NVIRILVATDNHLGYGEKDAVRGEDSFTAFEEILELAVSEDVDMILLGGDLFHDAVPSQN 72

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE-INYEDPNLNISIPVFAISGNHD 390
            +++  ++ LR    GDRP  LE+LSD  Q  +N  ++ +NYEDPNLNI+IPVF+I GNHD
Sbjct: 73   ALHKCIELLRRYTFGDRPVSLEILSDQGQCFHNAVNQSVNYEDPNLNIAIPVFSIHGNHD 132

Query: 391  DATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLH 570
            D +G   L +LD+L+ +GL+N FG+  +   + +SP+L++KG+++LALYG+S++ D RL 
Sbjct: 133  DPSGFGRLSSLDLLSTSGLVNYFGRWTDLTQVEISPVLMRKGESQLALYGLSHIHDGRLA 192

Query: 571  RLFRDGGVKFQRP-----------NIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLD 717
            RL +D  VKF  P           + + EDWF+L V+HQN A     + +PE  LP+FL 
Sbjct: 193  RLIKDFKVKFNCPENVANGEDGNESKEEEDWFHLLVVHQNRADRGPKNYLPEDLLPSFLH 252

Query: 718  FILWGHEHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPV 897
             ++WGHEH+C   P  N +  F V Q GSSV TSL+EGE   K + +L I    + ++P+
Sbjct: 253  LVIWGHEHDCRIEPEENAKKRFYVSQPGSSVPTSLSEGEAKKKHVGLLEIYKGKFKLKPL 312

Query: 898  ELKTVRPFVLREIILL----KTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILN 1065
             L+TVRPFV   ++L     +  L+ G AS   V  +  + VE  IERA  Q        
Sbjct: 313  PLETVRPFVYESVVLADHADELGLVEGDAS-TKVFKFAQERVEAMIERAVAQH------- 364

Query: 1066 SNRAITNLSNNATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFY 1245
                        T  P +  LPLIRLR+ Y+    + N  RF      ++ANV DVVQF 
Sbjct: 365  ------------TGHPKQPTLPLIRLRLLYTDESCMFNAIRFGEMLSTRVANVQDVVQFS 412

Query: 1246 K--KKTPTKSDN 1275
            K  K+T T++ N
Sbjct: 413  KVVKRTKTEAVN 424


>Q9GZJ8|MRE11|Q9GZJ8 (TrEMBL: Bombyx mori (Silk moth)) Mre11.
          Length = 610

 Score =  315 bits (807), Expect = 1e-84
 Identities = 185/502 (36%), Positives = 294/502 (58%), Gaps = 7/502 (1%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            DT+R+L+ +D H+G  ENDP+RG+D++  F+E+ ++A   DVD+I+ GGDLF   KP+  
Sbjct: 13   DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQAKPSVN 72

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDD 393
             M+   + +R  C+GD+P  +ELLSD  ++ +     +NYEDPNLNIS P+ +I GNHDD
Sbjct: 73   CMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR---TVNYEDPNLNISYPILSIHGNHDD 129

Query: 394  ATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHR 573
              G+  + +LD+L++TGL+N FGK  +   + +SP+LLQKG T+LALYG+S+++D+RL R
Sbjct: 130  PVGQGSVSSLDILSITGLVNYFGKWTDYTHVRISPVLLQKGLTRLALYGLSHLKDQRLSR 189

Query: 574  LFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHECIP 753
            LF +  V+ +RP+ +T DWFNLFV+HQNHA   +++ IPE  LP F   ++WGHEH+   
Sbjct: 190  LFAEKKVEMERPD-ETLDWFNLFVLHQNHADRGHSNYIPEGVLPTFRS-VVWGHEHDSHI 247

Query: 754  YPVHNPET---TFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFV 924
             P+   +T   +F V+Q GS+VATSLA GE   K   +L I   ++ + P+ L+TVRPF+
Sbjct: 248  CPMKGNKTEKDSFFVVQPGSTVATSLAAGEALPKHCGLLEIHKGNFKLTPLPLQTVRPFI 307

Query: 925  LREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNAT 1104
             + I+L          S+ ++ +   +E EK      ++F    +   N AI   S   T
Sbjct: 308  FKTIVL----------SEENIGSDDVNENEKV-----QEFLKNRV---NEAIDEASKLKT 349

Query: 1105 ADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDNKLT 1284
            AD  +  LPLIRL + Y    +  N  RF   F G +AN ND++   K+K       K+ 
Sbjct: 350  ADLRQPLLPLIRLSIFYERESQNFNRIRFGQNFNGLVANPNDLLIMKKEK-------KIR 402

Query: 1285 RKTKYDVDLIEENLHHKKTTELELQDIIRDFLQ----QTQLSLVPETEMNHAVKKFVEND 1452
             K + D +  E ++        +++ ++R + +      +LS++    +  AV+ F    
Sbjct: 403  EKRECDPE-EEGDMTGVAAEAADVESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKH 461

Query: 1453 DKQALNQFINQEIKRETKMLLD 1518
            ++  L +  +   +R    LL+
Sbjct: 462  NEDVLRRAFDAHKRRCIAALLE 483


>Q23255|MRE-11|MR11_CAEEL (SP: Caenorhabditis elegans) Double-strand
            break repair protein mre-11.
          Length = 772

 Score =  301 bits (772), Expect = 2e-80
 Identities = 184/461 (39%), Positives = 259/461 (56%), Gaps = 13/461 (2%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            D I++L+ TD H G  EN      DA  TF+E+  IA ++ VDMI+ GGDLFH N P+++
Sbjct: 108  DIIKILVATDIHCGYGENKANIHMDAVNTFEEVLQIATEQKVDMILLGGDLFHENNPSRE 167

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNG-FDEINYEDPNLNISIPVFAISGNHD 390
              + V + LR  C+   P  LE LSD + + N   F  +NY D NLN+ +P+F I GNHD
Sbjct: 168  VQHRVTQLLRQYCLNGNPIALEFLSDASVNFNQSVFGHVNYYDQNLNVGLPIFTIHGNHD 227

Query: 391  DATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLH 570
            D +G+ L  ALD+L  +GL+N FGK  N +   VSPILL+KG+T+LALYG+ + RD+RL 
Sbjct: 228  DLSGKGLT-ALDLLHESGLVNLFGKHSNIQEFIVSPILLRKGETRLALYGIGSQRDDRLV 286

Query: 571  RLFRDGGVKFQRPNIQTEDWFNLFVIHQN---HAAHTYTSS-IPESFLPNFLDFILWGHE 738
            R F++  + F RPN   EDWFNLFV+HQN    A H  T + +PES +P F D ++WGHE
Sbjct: 287  RAFKNNSISFLRPNAGAEDWFNLFVLHQNRPRRAMHRSTGNFLPESLIPQFFDLLIWGHE 346

Query: 739  HECIPYPVHNPETT-----FDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVEL 903
            HEC P P +   +      F +LQ GS+VATSL   E   K  F++ IKG+ ++ +P+ L
Sbjct: 347  HECKPDPQYVASSEAVGDGFYILQPGSTVATSLTPEEALQKNAFLIKIKGRKFASKPIPL 406

Query: 904  KTVRPFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAIT 1083
            +TVRP V  E++L K  + PG+          TD  + +  R   + + +     N  IT
Sbjct: 407  QTVRPMVCDELLLDK--IPPGSRP-----ILKTDRPKHTDGRYIDEIAIE--AKINEMIT 457

Query: 1084 NLSNNATADPIEKPLPLIRLRVEYSGGY---EIENVTRFSNRFVGKIANVNDVVQFYKKK 1254
              +  A   P +  LPLIRL+V Y G +      N  R   R+   +AN  D+V F KK 
Sbjct: 458  --TAKAKRRPRQPELPLIRLKVIYDGDWLNITPANAKRIGLRYENVVANAVDMV-FIKKN 514

Query: 1255 TPTKSDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDF 1377
               K     T   K   ++ +E     + +   LQ II D+
Sbjct: 515  NKPKEGKLQTENEKNITEMADE---MGQVSATNLQTIINDY 552


>Q8T8P1|MRE11|Q8T8P1 (TrEMBL: Trypanosoma brucei brucei) DNA repair
            protein Mre11.
          Length = 763

 Score =  249 bits (636), Expect = 9e-65
 Identities = 158/494 (31%), Positives = 263/494 (53%), Gaps = 13/494 (2%)
 Frame = +1

Query: 37   TIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAK-DKDVDMIIQGGDLFHINKPTKK 213
            T + L+T+DNH+G  E D  RGDD++ TF+E    A+ + +VD I+  GD FH NKP+  
Sbjct: 37   TFKFLVTSDNHLGYQERDSRRGDDSFTTFEECLRAARVEHEVDAILLAGDFFHDNKPSLG 96

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSL-NNGFDEINYEDPNLNISIPVFAISGNHD 390
             +      LRS  +GD+P    LLSDP ++   +     N++DPN+N+++P+F I GNHD
Sbjct: 97   CLARTSSLLRSYVLGDKPISFTLLSDPKRNFPTHPVPLANFQDPNINVALPIFMIHGNHD 156

Query: 391  DATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLH 570
            D  G +   ++D+L+  GL+N FG   + + I V P+LL+KG T +ALYG+ NVRD+RLH
Sbjct: 157  DPVGGTS--SIDILSTAGLVNYFGHTSSLDDIVVEPVLLKKGDTYIALYGLGNVRDDRLH 214

Query: 571  RLFRDGGVKFQRPNIQT-EDWFNLFVIHQNHAAHT---YTSSIPESFLPNF-LDFILWGH 735
            R FR   + F +P  +  +DWF + + HQN    +       I E+ L    +D ++WG+
Sbjct: 215  RCFRMKKLHFVQPKTEPGKDWFKILLFHQNRGVRSGGNMKCGIYETMLAGHGMDLVIWGN 274

Query: 736  EHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVR 915
            EHE    P  +P   FD++Q GS++ TSL+E E   KK  +L ++G  Y +    L+++R
Sbjct: 275  EHEQQMEP--SPSEGFDIIQPGSTILTSLSEHECNPKKYGVLEVRGGSYRVTGFPLRSIR 332

Query: 916  PFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            P V R + L + +  PG  +   V  +L   VE+ IE A +Q            ++ + +
Sbjct: 333  PVVRRTVELWRDN--PGCRTLDAVEDFLRSVVEQMIEEAEEQ------------VSRIPD 378

Query: 1096 NATADPIEKPLPLIRLRVEY----SGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPT 1263
            +          P++RL V++    S  +   N+ RF  +++  + N +++++  K K   
Sbjct: 379  DVLKFHPNIKFPIMRLAVDFTDPDSTTFPQPNINRFGQQYMDIVVNPSELLRPIKPKQVP 438

Query: 1264 K--SDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKK 1437
            +  S    T      V +   N    +T   E    + +   +   SL+ E+E++ AV  
Sbjct: 439  RVASSASATGGEAPVVPVPRLNTSDIRTKVAE----VFNANARDACSLLSESEVSAAVYA 494

Query: 1438 FVENDDKQALNQFI 1479
            F E  ++ A+++ I
Sbjct: 495  FAEKGERDAIDERI 508


>Q8WPP1|MRE11|Q8WPP1 (TrEMBL: Trypanosoma brucei) Mre11 protein.
          Length = 763

 Score =  249 bits (636), Expect = 9e-65
 Identities = 158/494 (31%), Positives = 263/494 (53%), Gaps = 13/494 (2%)
 Frame = +1

Query: 37   TIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAK-DKDVDMIIQGGDLFHINKPTKK 213
            T + L+T+DNH+G  E D  RGDD++ TF+E    A+ + +VD I+  GD FH NKP+  
Sbjct: 37   TFKFLVTSDNHLGYQERDSRRGDDSFTTFEECLRAARVEHEVDAILLAGDFFHDNKPSLG 96

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSL-NNGFDEINYEDPNLNISIPVFAISGNHD 390
             +      LRS  +GD+P    LLSDP ++   +     N++DPN+N+++P+F I GNHD
Sbjct: 97   CLARTSSLLRSYVLGDKPISFTLLSDPKRNFPTHPVPLANFQDPNINVALPIFMIHGNHD 156

Query: 391  DATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLH 570
            D  G +   ++D+L+  GL+N FG   + + I V P+LL+KG T +ALYG+ NVRD+RLH
Sbjct: 157  DPVGGTS--SIDILSTAGLVNYFGHTSSLDDIVVEPVLLKKGDTYIALYGLGNVRDDRLH 214

Query: 571  RLFRDGGVKFQRPNIQT-EDWFNLFVIHQNHAAHT---YTSSIPESFLPNF-LDFILWGH 735
            R FR   + F +P  +  +DWF + + HQN    +       I E+ L    +D ++WG+
Sbjct: 215  RCFRMKKLHFVQPKTEPGKDWFKILLFHQNRGVRSGGNMKCGIYETMLAGHGMDLVIWGN 274

Query: 736  EHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVR 915
            EHE    P  +P   FD++Q GS++ TSL+E E   KK  +L ++G  Y +    L+++R
Sbjct: 275  EHEQQMEP--SPSEGFDIIQPGSTILTSLSEHECNPKKYGVLEVRGGSYRVTGFPLRSIR 332

Query: 916  PFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSN 1095
            P V R + L + +  PG  +   V  +L   VE+ IE A +Q            ++ + +
Sbjct: 333  PVVRRTVELWRDN--PGCRTLDAVEDFLRSVVEQMIEEAEEQ------------VSRIPD 378

Query: 1096 NATADPIEKPLPLIRLRVEY----SGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPT 1263
            +          P++RL V++    S  +   N+ RF  +++  + N +++++  K K   
Sbjct: 379  DVLKFHPNIKFPIMRLAVDFTDPDSTTFPQPNINRFGQQYMDIVVNPSELLRPIKPKQVP 438

Query: 1264 K--SDNKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKK 1437
            +  S    T      V +   N    +T   E    + +   +   SL+ E+E++ AV  
Sbjct: 439  RVASSASATGGEAPVVPVPRLNTSDIRTKVAE----VFNANARDACSLLSESEVSAAVYA 494

Query: 1438 FVENDDKQALNQFI 1479
            F E  ++ A+++ I
Sbjct: 495  FAEKGERDAIDERI 508


>Q8SRV0|ECU05_1280|Q8SRV0 (TrEMBL: Encephalitozoon cuniculi)
            Double-strand break DNA repair protein (RAD32 homolog).
          Length = 567

 Score =  231 bits (588), Expect = 3e-59
 Identities = 155/504 (30%), Positives = 266/504 (52%), Gaps = 9/504 (1%)
 Frame = +1

Query: 40   IRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKSM 219
            +++L+T+DNH+G  E+DP+  DD++ TF+EI  IA+ + VD+++QGGDLFH N+P++  +
Sbjct: 1    MKILITSDNHLGYRESDPVLLDDSYDTFEEILGIAQRERVDLVLQGGDLFHENRPSRSCL 60

Query: 220  YHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDAT 399
               +   R  C+G+    L   S+ A         +N+ D N+ ISIPV +I GNHDD +
Sbjct: 61   NRTIGLFRRYCIGNERSGLR--SNLA---------LNFHDQNIGISIPVVSIHGNHDDPS 109

Query: 400  GESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHRLF 579
            G S++  +D+L   GL+N  GK    + I V P+LL+K + ++A+YG+ +++D RL+R+F
Sbjct: 110  GISMVSPIDILQSAGLVNYIGKYNLIDRIDVYPLLLEK-EYRVAIYGLGHIKDRRLYRMF 168

Query: 580  RDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNFLDFILWGHEHECIPYP 759
             +G + F RP    + W+N+ ++HQN              +  F D I++GHEHE +   
Sbjct: 169  CEGRIVFHRPE-DYDSWYNVLILHQNRIPRE-KEHFSSDLVEGFFDLIVYGHEHESMVV- 225

Query: 760  VHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIEPVELKTVRPFVLREII 939
                +    +LQ GS+V TSL EGE  DK  +IL I G++ ++E V+L++VRP +L  + 
Sbjct: 226  ----KGDCLILQPGSTVRTSLCEGERHDKYAYILRI-GEECTLEHVKLRSVRPLLLDTLR 280

Query: 940  LLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNNAT-ADPI 1116
            + + D +       + I  + D   K     NK+ ++ ++          SN A  A P+
Sbjct: 281  IEERDNVEEKVE--NKIRGMIDLGRKKESLFNKEITAIDVDTKRFKCRGDSNEACGAGPV 338

Query: 1117 EK--------PLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSD 1272
             K         +PL++L++E  G  E+ +  RFS +F G +AN +D++   +K       
Sbjct: 339  CKGYQLEEKTRIPLVKLKIELCGD-EVLDKHRFSAQFKGLVANPSDMLTISRK------- 390

Query: 1273 NKLTRKTKYDVDLIEENLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFVEND 1452
               TR+        EE         +E+  I+R  L   +  ++     + ++ +FV+ D
Sbjct: 391  ---TRRR-------EEVETQPMAERVEISQILRKILGNVEFGVLSRLGFSESLDEFVKGD 440

Query: 1453 DKQALNQFINQEIKRETKMLLDID 1524
                 N F+    K   K++  +D
Sbjct: 441  S----NAFMGMVRKNIEKVVNAVD 460


>Q9BS79||Q9BS79 (TrEMBL: Homo sapiens (Human)) Hypothetical protein
           (MRE11 meiotic recombination 11 homolog A) (S.
           cerevisiae).
          Length = 206

 Score =  207 bits (528), Expect = 3e-52
 Identities = 99/195 (50%), Positives = 141/195 (72%), Gaps = 3/195 (1%)
 Frame = +1

Query: 34  DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
           +T ++L+ TD H+G  E D +RG+D + T DEI  +A++ +VD I+ GGDLFH NKP++K
Sbjct: 11  NTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRK 70

Query: 214 SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDE---INYEDPNLNISIPVFAISGN 384
           +++  ++ LR  CMGDRP + E+LSD  QS+N GF +   +NY+D NLNISIPVF+I GN
Sbjct: 71  TLHTCLELLRKYCMGDRPVQFEILSD--QSVNFGFSKFPWVNYQDGNLNISIPVFSIHGN 128

Query: 385 HDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDER 564
           HDD TG   L ALD+L+  G +N+FG+  + E I +SP+LLQKG TK+ALYG+ ++ DER
Sbjct: 129 HDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDER 188

Query: 565 LHRLFRDGGVKFQRP 609
           L+R+F +  V   RP
Sbjct: 189 LYRMFVNKKVTMLRP 203


>Q86C23||Q86C23 (TrEMBL: Entamoeba histolytica) Mre11.
          Length = 603

 Score =  182 bits (462), Expect = 1e-44
 Identities = 141/502 (28%), Positives = 231/502 (46%), Gaps = 21/502 (4%)
 Frame = +1

Query: 34   DTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKK 213
            +T ++L+ +D H+GA E      DD +  F+EI   A  +DVD+I+  GD F    P+K 
Sbjct: 6    NTFKILICSDTHLGAGEKSHCLKDDCYLAFEEILQQANQEDVDLILHSGDFFDDQNPSKY 65

Query: 214  SMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFD-EINYED----PNLNISIPVFAIS 378
             +   M+ +R   MG           P  S +  +  E N ED     N  I  P++ I 
Sbjct: 66   CLTKTMELMRKYLMG----------KPKNSFDVAYTYEHNQEDNGFSMNQGIKYPMYVIH 115

Query: 379  GNHDDATGESLLLALDVLAVTGLINNFGKVKNTEAIT---------VSPILLQKGQTKLA 531
            GNHD  +G   +  LD+L   GL+N  GK ++   I          +SPILLQKG T++A
Sbjct: 116  GNHDIPSGIEHVAGLDILQTAGLVNFIGKAEDISEIDNKTDQTILHLSPILLQKGTTRIA 175

Query: 532  LYGMSNVRDERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPESFLPNF 711
            LYGMS  ++E ++RL+    V+   P+    D F + +IHQ+       ++ PE  L + 
Sbjct: 176  LYGMSYKKNEEMNRLWASSQVQIDEPD---GDVFKILLIHQDRILRNTLTTFPEELLKDR 232

Query: 712  LDFILWGHEHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYSIE 891
             + I++GHEH C         T   ++Q GSS   S+ E E A+K I + +I G   ++ 
Sbjct: 233  FNLIVFGHEH-CSQV---EEGTDVQIIQTGSSFPLSICEFEKAEKFIGLAHINGMKINMN 288

Query: 892  PVELKTVRPFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSN 1071
             + L+ VR  V  E++ + + +I G+A+   V  Y+ +EV+   +  N    +       
Sbjct: 289  KIALRNVRE-VFYEVVQM-SQMIEGSANLEMVEHYIREEVQNFFDHVNTHSKTM------ 340

Query: 1072 RAITNLSNNATADPIEKPLPLIRLRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKK 1251
                              LPL R+ +EY     I N+ + +  F   I N  D ++  KK
Sbjct: 341  ------------------LPLARIIIEYKSLGCIPNLRKMAFEFEKNIVNKGDCIKLKKK 382

Query: 1252 --KTPTKSDNKLTRKTKYDV----DLIEEN-LHHKKTTELELQDIIRDFLQQTQLSLVPE 1410
              K   KS+ K+     YDV    D ++E+ L  ++  ++E       ++ +      P+
Sbjct: 383  IQKREKKSNKKIVDDDLYDVFFDEDFMDEDFLARRRAAQIEA------YIAEEMKLKTPK 436

Query: 1411 TEMNHAVKKFVENDDKQALNQF 1476
            T    A++K +E       N +
Sbjct: 437  TIPLKAIEKVIEQVGNNQENDY 458


>Q8I263|PFA0390W|Q8I263 (TrEMBL: Plasmodium falciparum (isolate 3D7))
            DNA repair exonuclease, putative.
          Length = 1118

 Score =  141 bits (355), Expect = 3e-32
 Identities = 84/237 (35%), Positives = 134/237 (56%), Gaps = 5/237 (2%)
 Frame = +1

Query: 358  IPVFAISGNHDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALY 537
            IP + I GNHD       +  LD+L ++ LIN  GK  N   I V PILL K ++K+++Y
Sbjct: 582  IPFYTIHGNHDYPYSYEYISPLDILNISNLINYIGK-NNLNNIVVKPILLNKYKSKISIY 640

Query: 538  GMSNVRDERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQN-HAAHTYTSS----IPESFL 702
             +  ++DERL+R F +  VKF  P+   ++  N+ V+HQN +  + Y ++    I ESF+
Sbjct: 641  AVGWMKDERLYRSFENNEVKFILPS-DYKNRINILVLHQNRYIRNAYGNNTKNFIKESFI 699

Query: 703  PNFLDFILWGHEHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDY 882
            P F+D ++WGHEH   PY   +   +F  +Q GSSV TS+   E  DK I +L IK + +
Sbjct: 700  PKFIDLVIWGHEHFSKPYLEESILNSFYNIQLGSSVRTSICPNEYGDKFIGLLEIKNQRF 759

Query: 883  SIEPVELKTVRPFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQ 1053
                + L+TVRPF +++I L   +L     S++ +  +L ++    +E+    FS +
Sbjct: 760  RFLKINLETVRPFEMKDIKLADYEL--NFKSESVLKEFLHEQTHAILEKIKNNFSHE 814



 Score = 70.1 bits (170), Expect = 1e-10
 Identities = 39/110 (35%), Positives = 70/110 (63%), Gaps = 2/110 (1%)
 Frame = +1

Query: 37  TIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
           T+++LL TDNH+G  EN+ I+  D++ +F+EI  IAK  +VDMI+  GDLFH NK ++ +
Sbjct: 350 TLKILLCTDNHLGYKENNSIQKKDSFNSFEEILFIAKKLNVDMILNSGDLFHKNKVSEYT 409

Query: 217 MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGF--DEINYEDPNLNISI 360
           ++  M  +R  C  +   + E+  D   ++NN    +++N +D +++ +I
Sbjct: 410 LFKSMYIIRKYCHINEN-DKEMQQD--DNINNNIYPNDLNNDDKSVSKAI 456


>Q86C19||Q86C19 (TrEMBL: Giardia lamblia (Giardia intestinalis))
            Mre11.
          Length = 817

 Score = 60.8 bits (146), Expect = 6e-08
 Identities = 96/444 (21%), Positives = 174/444 (39%), Gaps = 45/444 (10%)
 Frame = +1

Query: 43   RVLLTTDNHVG--AFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
            R+ L TD H+G  A    P    + +   +E   +A+      I+  GD F+ N+ + K 
Sbjct: 9    RIALFTDTHLGFTAPSARPCNAHENYLLLEECLCLARKLGAHAILHAGDFFNQNRLSSKK 68

Query: 217  MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDA 396
            +   + +LR                        +   ++ D +   SIP+  I GNHD+ 
Sbjct: 69   VIKAICALRR-----------------------YGVSSFADHSDGDSIPMALIYGNHDNN 105

Query: 397  TGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGM----------- 543
                    L +L   G ++  G  +  +++T+ P+    G  +L +YG+           
Sbjct: 106  DK-----ILGLLEAAGAVSLLGHTQAGKSLTLHPLCQVVGGVELVVYGLDYHKAWQRDVA 160

Query: 544  ----------SNVRDERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYTSSIPE 693
                      S + DE + R  + GG +  R        +   V+HQ+++       I  
Sbjct: 161  PEISFAPAARSALEDEAVGRGAK-GGRRHAR--------YTFLVLHQDYSDQVGRDKISL 211

Query: 694  SFLPNF---------LDFILWGHEHECIPYPVHNPETTFDVLQAGSSVATSLAEGEVADK 846
            SF+  +         +DF+  GHEH+  P        TF +L  GS    S        +
Sbjct: 212  SFVDQWNHTHAPEERIDFVYIGHEHDETP---PRDGETFTLLMPGSPHRQS--------R 260

Query: 847  KIFILNIKGKDYSIE----PVELKTVRPFVLREIILLKTDLIPGA----ASKADVIAYLT 1002
            K  +LN++ +D +      P++ K +    LR   L + +L+ G+     +K+  I    
Sbjct: 261  KGNLLNVRQEDRNFYLLTLPLQRKCLDSPPLRYCHLNRYNLLSGSFYHIGAKSIDIVTEK 320

Query: 1003 DEVEKSIERANKQFSSQNILNSNRAITNLSNNATADPIEKPLPLI-----RLRVEYSGGY 1167
              + KS     K     N  + N  I  ++N+A +   ++ +P I       R  YS G+
Sbjct: 321  YRISKSEHDYTKIAECIN-TSINSEIEAVTNHAASLLCKRIMPCIIDLQKHCRELYSNGH 379

Query: 1168 EIENVTRFSNRFVGKIANVNDVVQ 1239
             IE++       V  +A++  V+Q
Sbjct: 380  SIESI-------VASLASLRSVMQ 396


>Q8TRL2|MA1163|Q8TRL2 (TrEMBL: Methanosarcina acetivorans) DNA
           repair exonuclease.
          Length = 614

 Score = 58.2 bits (139), Expect = 4e-07
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 5/287 (1%)
 Frame = +1

Query: 40  IRVLLTTDNHVGAFE-NDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
           IR+L T D H+G  + +  +R  D +K F+ +   A D  VD ++  GDLF    PT + 
Sbjct: 5   IRILHTADTHLGYRQYHSEVRRQDFFKAFETVIQDAVDMQVDAVVHAGDLFDSRNPTLED 64

Query: 217 MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDA 396
           +   M  L           L+                        + IP F I GNH+  
Sbjct: 65  LLETMNIL---------SRLKA-----------------------VDIPFFGIVGNHESK 92

Query: 397 TGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHRL 576
                   LD+    GL    GK         +P L+  G T   +YG+ +V   ++   
Sbjct: 93  QNTQW---LDLFEEMGLAERLGK---------TPKLV--GNT--TIYGIDSVPKSKIPLY 136

Query: 577 FRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTYT----SSIPESFLPNFLDFILWGHEHE 744
              G   F+ P+   E+   L V+HQ      Y     + + E+ LP  +D IL G  H+
Sbjct: 137 DYSG---FELPDSLPENCKKLLVMHQIVQPFPYADWDCAEVLEN-LPFKVDAILLGDYHK 192

Query: 745 CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYS 885
                V   ET      +GS+   S +E E     I  L+ +G + S
Sbjct: 193 YEKIKVGEEETW--ATYSGSTERNSASENEPRSYNIITLSGEGLEIS 237


>Q8PUY5|MM2193|Q8PUY5 (TrEMBL: Methanosarcina mazei (Methanosarcina
           frisia)) DNA repair protein.
          Length = 617

 Score = 55.5 bits (132), Expect = 3e-06
 Identities = 71/287 (24%), Positives = 109/287 (37%), Gaps = 5/287 (1%)
 Frame = +1

Query: 40  IRVLLTTDNHVGAFE-NDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
           IR+L T D H+G  + +  +R  D +K F+ +   A D  VD ++  GDLF    PT + 
Sbjct: 5   IRILHTADTHLGYRQYHSEVRRQDFFKAFETVIKDAVDMQVDAVVHAGDLFDSRNPTLED 64

Query: 217 MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDA 396
           +   M  L           L++                        +IP F I GNH+  
Sbjct: 65  LLETMNVL---------SRLKV-----------------------ANIPFFGIVGNHESK 92

Query: 397 TGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHRL 576
                   LD+    GL    GK               K    +A+YG+ +V   ++  L
Sbjct: 93  QSTQW---LDLFEEMGLAGRLGKA-------------PKMVGDVAIYGIDSVPKSKI-PL 135

Query: 577 FRDGGVKFQRPNIQTEDWFNLFVIHQNHAAHTY----TSSIPESFLPNFLDFILWGHEHE 744
           F   G  F+ P    E+   L V+HQ      +     + + E+ LP   D +L G  HE
Sbjct: 136 FDYSG--FEIPESLPENCRKLLVMHQIMQPSPFPDWDCAEVIEN-LPFKADAVLLGDYHE 192

Query: 745 CIPYPVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKGKDYS 885
                V     T+    +GS+   S +E E     I  L+ +G + S
Sbjct: 193 YEKIKVGESWVTY----SGSTERNSASEKEPRSYSIITLSGEGLEIS 235


>Q8NKQ0|MRE11|Q8NKQ0 (TrEMBL: Sulfolobus acidocaldarius) Mre11
            protein.
          Length = 382

 Score = 55.5 bits (132), Expect = 3e-06
 Identities = 94/460 (20%), Positives = 177/460 (38%), Gaps = 23/460 (5%)
 Frame = +1

Query: 40   IRVLLTTDNHVGAFE-NDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
            +++L  +D H+G  + N   R  D + TF ++  IA ++ V  +I  GDLF +N P  ++
Sbjct: 1    MQLLHISDTHLGKRQYNLESREKDVYDTFTQLIDIAINEHVKAVIHTGDLFDVNNPPNRA 60

Query: 217  MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDA 396
              H +K            EL+ L D                     +IP   I+G+HD  
Sbjct: 61   KLHAIK------------ELKRLKDH--------------------NIPFICIAGDHDSP 88

Query: 397  TGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMSNVRDERLHRL 576
              +  +    +L    LI    K+ N   +             + +YG+S++ +  ++ L
Sbjct: 89   KRKEEIYPQRILEEFNLIKILQKIDNRVKL-----------ENVEVYGISHISNVSVNDL 137

Query: 577  FRDGGVKFQRPNIQTEDWFNLFVIHQ---NHAAHTYTSSIPESFLPNFLDFILWGHEHEC 747
                  K Q   ++ E   ++ ++HQ    +  +     I  S LP        GH H  
Sbjct: 138  ------KEQLSKVKPETRKSILMLHQGIRTYLPYQGAWQIELSDLPKGFSLYAVGHLH-- 189

Query: 748  IPYPVHNPETTFDVLQAGSSVATS-----LAEGEVAD-----KKIFILNIKGKDYSIEPV 897
                        D L  G+ +  +     + E E+ D     K   ++++ G   SI  +
Sbjct: 190  --------SRRKDYLDGGALIEIAGSPDIMREEEIEDYQKSKKGATLIDMSGDLPSINYI 241

Query: 898  ELKTVRPFVLREIILLKTDLIPGAASKADVIAYLTDEVEKSIERANKQFSSQNILNSNRA 1077
             +       +R+ ++L  ++               D++E+SIE   ++   +N+ N  + 
Sbjct: 242  NVN------IRDQLVLDINV---------------DKIEQSIESVIQKL-KENVKNDKKP 279

Query: 1078 ITNLSNNATADPIEKPLPLIRLRV--EYSGGYEI--ENVT-----RFSNRFVGKIANVND 1230
            I ++    T  PI K + + +L+   +Y   Y I   N+          +     +++ND
Sbjct: 280  ILHIELEGTV-PIRKDVLMTKLQALRDYVEHYRIYKNNIVSIKEENLKTKLKTTYSSLND 338

Query: 1231 VVQFYKKKTPTKSDNKLTRKTKYDVDLIEENLHHKKTTEL 1350
            ++  Y      K       +TK  +D+I E    KK  EL
Sbjct: 339  IIADY-----LKGIGYTDEETKIIIDIINEE-DEKKVEEL 372


>O29231|AF1031|O29231 (TrEMBL: Archaeoglobus fulgidus) DNA repair
           protein RAD32 (RAD32).
          Length = 443

 Score = 53.5 bits (127), Expect = 1e-05
 Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
 Frame = +1

Query: 61  DNHVGAFE-NDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKSMYHVMKS 237
           D H+G  + N P R +D  K F  I   A + + D ++  GDLFH + P+ +++   +++
Sbjct: 8   DVHLGYEQYNQPWRAEDFAKAFKVIAEKAVESNADFVVIAGDLFHRSLPSPRTIKEAVET 67

Query: 238 LRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHD----DATGE 405
           L                         F + N         IPVFA+ GNHD    D +  
Sbjct: 68  LWM-----------------------FRKEN---------IPVFAVEGNHDKTSRDISAY 95

Query: 406 SLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKG 516
            LL +L +L V GL  N  + +N E++ +  + L KG
Sbjct: 96  HLLESLGLLNVLGLRRNPVRGENVESLRIQNVYLVKG 132


>Q97WG9|RAD32/MRE11|Q97WG9 (TrEMBL: Sulfolobus solfataricus) DNA
           repair protein (rad32/mre11) (EC 3.1.-.-).
          Length = 381

 Score = 43.9 bits (102), Expect = 0.008
 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
 Frame = +1

Query: 40  IRVLLTTDNHVGAFENDPI-RGDDAWKTFDEITTIAKDKDVDMIIQGGDLFHINKPTKKS 216
           +++L  +D H+G  +   + R  D +  F ++  IA  + VD+II  GDLF ++ PT  +
Sbjct: 2   VQILHISDTHLGKRQYSLVEREKDIYDIFSQLVDIAIKEHVDVIIHSGDLFDVSSPTTNA 61

Query: 217 MYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPVFAISGNHDDA 396
           +   +K L+             L D                    ++IP  +I G+HD  
Sbjct: 62  LVMAIKILKR------------LKD--------------------VNIPFLSIPGDHDTP 89

Query: 397 TGESLLLALDVLAVTGLI 450
             +  L+  ++L+   LI
Sbjct: 90  KRKGYLIPHNILSELDLI 107


>O26641|MTH541|O26641 (TrEMBL: Methanobacterium thermoautotrophicum)
           RAD32 related protein.
          Length = 587

 Score = 43.9 bits (102), Expect = 0.008
 Identities = 66/315 (20%), Positives = 118/315 (37%), Gaps = 11/315 (3%)
 Frame = +1

Query: 7   LVERIEPGPDTIRVLLTTDNHVGAFENDPIRGDDAWKTFDEITTIAKDKDVDMIIQGGDL 186
           ++E    G    R    +D H+GA ++  +R +  ++ F      A  KDVD +I  GDL
Sbjct: 160 MIEFYRVGLSMYRFAHLSDCHLGAQKHPDLR-ELEFEAFRMALDDALQKDVDFMIIAGDL 218

Query: 187 FHINKPTKKSMYHVMKSLRSNCMGDRPCELELLSDPAQSLNNGFDEINYEDPNLNISIPV 366
           FH N P  +++      LR                                      +P+
Sbjct: 219 FHSNIPNMETVKRATLELRR--------------------------------VREAGVPI 246

Query: 367 FAISGNHDDATGESLLLALDVLAVTGLINNFGKVKNTEAITVSPILLQKGQTKLALYGMS 546
           +   G+HD +   + +  +D+L   G+I+   +    + + +   + +K   K+   G+S
Sbjct: 247 YVNYGSHDYSPSSTSM--IDILESAGVIDKVVRPIPGKKLGLEFTVDEKTGAKIT--GLS 302

Query: 547 NVRDERLHRLFRDGGVKFQRPNIQTEDWFNLFVIHQ-----NHAAHTYTSSIPESFLPNF 711
                R   L  +  +K  R  ++ ED F +F+ H               S+  +  P  
Sbjct: 303 G----RSRTLEAEYFMKLDREALEAEDGFRIFLFHSAITQFKPVDLADMESVDLNLFPRG 358

Query: 712 LDFILWGHEHECIPY------PVHNPETTFDVLQAGSSVATSLAEGEVADKKIFILNIKG 873
            ++   GH H    Y      P+  P T F       S A  L E    + + + L ++ 
Sbjct: 359 FEYYAGGHVHRKGCYIEEGYGPIVYPGTLF------GSYAGDLEENARGETRGYYL-VEF 411

Query: 874 KDYSIEPVELKTVRP 918
            D + EP E + +RP
Sbjct: 412 TDRAREP-EFREIRP 425


>Q8I525|PFL1930W|Q8I525 (TrEMBL: Plasmodium falciparum (isolate 3D7))
            Hypothetical protein.
          Length = 5767

 Score = 42.4 bits (98), Expect = 0.022
 Identities = 53/221 (23%), Positives = 89/221 (40%), Gaps = 4/221 (1%)
 Frame = +1

Query: 973  SKADVIAYLTDEVEKSIERANKQFSSQNILNSNRAITNLSNN----ATADPIEKPLPLIR 1140
            +K D +    ++ E+ IE+  + +  Q  +N N  I+N +NN     +++  EK L    
Sbjct: 3455 NKLDNMNIYVNKKEREIEKLKEIYGDQFSINKNSYISNSNNNDNKRNSSNLSEKHL---H 3511

Query: 1141 LRVEYSGGYEIENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDNKLTRKTKYDVDLIEE 1320
            ++ EY    E+ N  +FS   +    N  D +     K   K   KL     +D D I +
Sbjct: 3512 IKEEYK---ELLNEYKFSLNLLNDTKNKLDTL-----KREKKDMEKLKELQIHDKDYIIQ 3563

Query: 1321 NLHHKKTTELELQDIIRDFLQQTQLSLVPETEMNHAVKKFVENDDKQALNQFINQEIKRE 1500
            NL   K    EL++ + +  +                +K +E ++    N  +   +  E
Sbjct: 3564 NL---KGINRELENNLNEIKKSFN-------------EKILEKENIIEKNNDLINNLNEE 3607

Query: 1501 TKMLLDIDIDENEFHGADEKHAKTAFKHVLLQLKNINGPIN 1623
              ML  I I  N F            K + LQ+KN+N  IN
Sbjct: 3608 IIMLKSIKIKNNNF-----------IKELELQIKNLNNEIN 3637



 Score = 37.4 bits (85), Expect = 0.71
 Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
 Frame = +1

Query: 1171 IENVTRFSNRFVGKIANVNDVVQFYKKKTPTKSDNKLTR----KTKYDVDLIEENLHHKK 1338
            I ++ ++ N  +G+I   ND+    K+    +  N   R      KYD D+   N+HH  
Sbjct: 2678 INSLDKYGNNKMGEIKKSNDIRNTLKENELNEKPNVAGRISSHTNKYDQDVSSNNVHHMN 2737

Query: 1339 TTELE-LQDIIRDFLQQTQLSLVPETEMNHAVKKFVENDDKQALNQFINQEIKRETKMLL 1515
               ++ L+D   D +++ +  +   +  N  +K  V+ ++ + LN  I  + K    ++ 
Sbjct: 2738 NMSVKSLEDHHDDIMEKMKNDMNDLSIENDLLK--VKINELEQLNSNIFNDNKDLINIIS 2795

Query: 1516 DIDID--------ENEFHGADEKHAKTAFKHVLLQLK 1602
            +I+ D        EN  +  D K     ++++L++ K
Sbjct: 2796 NIENDKKGISDSKENNINMLDMKDIHNNYENLLMENK 2832


  Database: sptrembl
    Posted date:  Oct 14, 2003  6:47 PM
  Number of letters in database: 339,323,595
  Number of sequences in database:  1,070,300
  
Lambda     K      H
   0.316    0.136    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 525,014,862
Number of Sequences: 1070300
Number of extensions: 10828117
Number of successful extensions: 38138
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35662
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37929
length of database: 339,323,595
effective HSP length: 128
effective length of database: 202,325,195
effective search space used: 111885832835
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)