BLASTX 2.2.6 [Apr-09-2003]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Candida_albicans_chr7-f2-38507-39679-13
         (1170 letters)

Database: sptrembl 
           1,070,300 sequences; 339,323,595 total letters

Searching.................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Q08913|YOR390W|Q08913 (TrEMBL: Saccharomyces cerevisiae (Baker's...   148   1e-34
Q08991|YPL279C|Q08991 (TrEMBL: Saccharomyces cerevisiae (Baker's...   147   2e-34
Q9UTS8|SPAC977.11|Q9UTS8 (TrEMBL: Schizosaccharomyces pombe (Fis...   118   2e-25
Q8RYE2|AT2G41705|Q8RYE2 (TrEMBL: Arabidopsis thaliana (Mouse-ear...    54   5e-06
Q9HW19|CRCB|CRCB_PSEAE (SP: Pseudomonas aeruginosa) Protein crcB...    50   7e-05
Q8CS29|SE1451|Q8CS29 (TrEMBL: Staphylococcus epidermidis) Conser...    45   0.001
Q8DPG7|CRCB|Q8DPG7 (TrEMBL: Streptococcus pneumoniae (strain ATC...    45   0.002
Q89Z03|CRCB|CRCB_BACTN (SP: Bacteroides thetaiotaomicron) Protei...    43   0.008
Q97QC5|SP1294|Q97QC5 (TrEMBL: Streptococcus pneumoniae) CrcB pro...    42   0.014
Q8Y5I1|CRCB1|CRB1_LISMO (SP: Listeria monocytogenes) Protein crc...    41   0.024
Q8NW04|CRCB|CRCB_STAAW (SP: Staphylococcus aureus (strain MW2)) ...    41   0.032
Q99T86|CRCB|CRCB_STAAM (SP: Staphylococcus aureus (strain N315))...    41   0.032
Q929T7|CRCB1|CRB1_LISIN (SP: Listeria innocua) Protein crcB homo...    40   0.041
Q82U09|NE1704|Q82U09 (TrEMBL: Nitrosomonas europaea) CRCB protein.     40   0.054
Q8DPG6|CRCB|Q8DPG6 (TrEMBL: Streptococcus pneumoniae (strain ATC...    39   0.092
Q97QC4|SP1295|Q97QC4 (TrEMBL: Streptococcus pneumoniae) CrcB pro...    39   0.092
Q925U7||Q925U7 (TrEMBL: Mus musculus (Mouse)) Ileal sodium-depen...    39   0.16 
P70172|SLC10A2|P70172 (TrEMBL: Mus musculus (Mouse)) Ileal NA+-d...    39   0.16 
P46491|CRCB|CRCB_HAEIN (SP: Haemophilus influenzae) Protein crcB...    36   0.78 
Q8TJ54|CRCB1|CRB1_METAC (SP: Methanosarcina acetivorans) Protein...    36   0.78 
Q9FC37|CRCB2|CRB2_STRCO (SP: Streptomyces coelicolor) Protein cr...    36   1.0  
Q9CKI7|CRCB|CRCB_PASMU (SP: Pasteurella multocida) Protein crcB ...    36   1.0  
Q815R5|BC5068|Q815R5 (TrEMBL: Bacillus cereus (strain ATCC 14579...    35   1.3  
Q97IQ3|CRCB1|CRB1_CLOAB (SP: Clostridium acetobutylicum) Protein...    35   1.3  
P43129|FRE|FRE_PHOLU (SP: Photorhabdus luminescens (Xenorhabdus ...    35   1.3  
Q8XGH9|CRCB|CRCB_SALTY (SP: Salmonella typhi) Protein crcB homolog.    35   1.7  
Q8TW26|CRCB|CRCB_METKA (SP: Methanopyrus kandleri) Protein crcB ...    35   1.7  
Q8RYS0|OSJNBA0026J14.14|Q8RYS0 (TrEMBL: Oryza sativa (japonica c...    34   3.0  
Q81XC0|BA5320|Q81XC0 (TrEMBL: Bacillus anthracis (strain Ames)) ...    34   3.0  
Q62633|SLC10A2|NTCI_RAT (SP: Rattus norvegicus (Rat)) Ileal sodi...    34   3.0  

>Q08913|YOR390W|Q08913 (TrEMBL: Saccharomyces cerevisiae (Baker's
            yeast)) Chromosome XV reading frame ORF YOR390W.
          Length = 375

 Score =  148 bits (374), Expect = 1e-34
 Identities = 105/370 (28%), Positives = 173/370 (46%), Gaps = 47/370 (12%)
 Frame = +1

Query: 199  KTQKYYPVILNIVHGAIWGVLVRKGLMLLTTYSGSFLSG--VIWANFAACVVMGLAIDGE 372
            K   Y  V        I G   R+ +  L+TY+ +F++   V+W+N ++C++MG+     
Sbjct: 11   KLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLN 70

Query: 373  VF-WIRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAAD-TDIGVRHH-- 540
             + W+     KD+       ++ G+TTG+CG +SSFSS++LE F  + + T+  + +H  
Sbjct: 71   AYTWM-----KDHQ-----VLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTK 120

Query: 541  YPNGAYGIMQFLAVILAQFGLS----IMGFHMGKQFLAVVDN------YLPLVT------ 672
             PN AYGIM+FL+V+L    +S    I G  +GK+ +    +      Y P         
Sbjct: 121  LPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENA 180

Query: 673  ------------------------KRIYKVLELTSMILGVVLVVITCILIGVKKQGSWRS 780
                                    K+ + +++  +  L   L+++  +L    +  S   
Sbjct: 181  GDVDTQEMEKNILEFKFKTPAPFFKKFFDIVDKLAYALAFPLIILFVVLCAYYENYSRGK 240

Query: 781  WTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKG 960
            WT   LF  F   LRY+L++  N     FPLGTF AN              RGK      
Sbjct: 241  WTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTD 300

Query: 961  HIVTNTI-ALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVLI 1137
              + N++ + H++  L  GFCG L+T+STF+ E + L  +    Y T+SI + +  +V+ 
Sbjct: 301  VPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIAISYCLLVIT 360

Query: 1138 LGSYNWSVGL 1167
            LGSY W+ GL
Sbjct: 361  LGSYAWTRGL 370


>Q08991|YPL279C|Q08991 (TrEMBL: Saccharomyces cerevisiae (Baker's
            yeast)) Chromosome XVI reading frame ORF YPL279C.
          Length = 375

 Score =  147 bits (372), Expect = 2e-34
 Identities = 106/370 (28%), Positives = 173/370 (46%), Gaps = 47/370 (12%)
 Frame = +1

Query: 199  KTQKYYPVILNIVHGAIWGVLVRKGLMLLTTYSGSFLSG--VIWANFAACVVMGLAIDGE 372
            K   Y  V        I G   R+ +  L+TY+ +F++   V+W+N ++C++MG+     
Sbjct: 11   KLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLN 70

Query: 373  VF-WIRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAAD-TDIGVRHH-- 540
             + W+     KD+       ++ G+TTG+CG +SSFSS++LE F  + + T+  + +H  
Sbjct: 71   AYTWM-----KDHQ-----VLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTK 120

Query: 541  YPNGAYGIMQFLAVILAQFGLS----IMGFHMGKQFLAVVDN------YLPLVT------ 672
             PN AYGIM+FL+V+L    +S    I G  +GK+ +    +      Y P         
Sbjct: 121  LPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENA 180

Query: 673  ------------------------KRIYKVLELTSMILGVVLVVITCILIGVKKQGSWRS 780
                                    K+ + V++  +  L   L+++  +L    +  S   
Sbjct: 181  GDVDTQEMEKNILEFKFKTPAPFFKKFFDVVDKLAYALAFPLIILFVVLCAYYENYSRGK 240

Query: 781  WTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKG 960
            WT   LF  F   LRY+L++  N     FPLGTF AN              RGK      
Sbjct: 241  WTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTD 300

Query: 961  HIVTNTI-ALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVLI 1137
              + N++ + H++  L  GFCG L+T+STF+ E + L  +    Y T+SI + +  +V+ 
Sbjct: 301  IPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIGISYCLLVIT 360

Query: 1138 LGSYNWSVGL 1167
            LGSY W+ GL
Sbjct: 361  LGSYAWTRGL 370


>Q9UTS8|SPAC977.11|Q9UTS8 (TrEMBL: Schizosaccharomyces pombe (Fission
            yeast)) Hypothetical protein.
          Length = 311

 Score =  118 bits (295), Expect = 2e-25
 Identities = 89/330 (26%), Positives = 152/330 (46%), Gaps = 9/330 (2%)
 Frame = +1

Query: 202  TQKYYPVILNIVHGAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGEVFW 381
            TQ Y+ ++      ++ G L R GL  L TY G+  SG++W  F  CV+MG      VF+
Sbjct: 4    TQSYFCIM------SMLGTLARLGLTALNTYPGAPFSGLLWVQFVGCVIMGFCQTESVFF 57

Query: 382  IRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAYG 561
             R       P   A      +TTGFCG++++FSS +L+ F   A+ D   R       Y 
Sbjct: 58   PR-------PKHNA-TFLLAITTGFCGSLTTFSSWMLQMFTGMANLDPFERR---GRGYS 106

Query: 562  IMQFLAVILAQFGLSIMGFHMGKQFLAVVDNYLPLVTKRIYKVLELTSMILGVVLVVIT- 738
             +  ++  +    +++     GKQ       +        + +   T +++ V+L++++ 
Sbjct: 107  FLSVVSDFMVTMCIAMSSLIWGKQIGKTTGQWRIGKVAFAWPIPAHTHIVVRVLLLLLSI 166

Query: 739  CILIGVKKQGSW------RSWTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXX 900
            C  +G     ++      R   FS++F+PF AL R YL++FLN+     P GT  AN   
Sbjct: 167  CFFVGAAFYTAYTTNVTHRGIGFSLIFSPFAALTRLYLARFLNSPQYFIPYGTLCANVFA 226

Query: 901  XXXXXXXXXXXRGKLPGGKGHIVTN--TIALHVLEGLDDGFCGGLTTVSTFVVELFGLKT 1074
                       +          +T+   ++  V+ G+ +GFC  L+T+STF  EL  +  
Sbjct: 227  TLLLSIMYMIPQ----------ITHCTPVSRSVMYGIQNGFCAVLSTLSTFSNELHTMPI 276

Query: 1075 LFSYRYGTISILVCFAGVVLILGSYNWSVG 1164
              +Y Y  IS+ + F+  V++ G+  W  G
Sbjct: 277  KRAYIYCIISVAISFSICVIVDGATAWGHG 306


>Q8RYE2|AT2G41705|Q8RYE2 (TrEMBL: Arabidopsis thaliana (Mouse-ear
            cress)) Expressed protein (Hypothetical protein).
          Length = 461

 Score = 53.5 bits (127), Expect = 5e-06
 Identities = 87/387 (22%), Positives = 146/387 (37%), Gaps = 29/387 (7%)
 Frame = +1

Query: 91   RTIQSDLVDIEAESISSALPEGFNYEKKTTATRFLDKTQKYYPVILNIVHGAIWGVLVRK 270
            +T+  D+      + S   PE  N  K+    R L K+ +Y   ++++    I+G + R 
Sbjct: 102  KTLPEDITASPLPTKSLLSPEINNSGKEEE--RVLPKSLEYISCLIHLAVFGIFGAITRY 159

Query: 271  GLMLL-------TTYSGSFLSGVIWANFAACVVMGLAIDGEVFWIRLLEEKDYPNKGAIP 429
             L  L        T  GS L   + +N     +MG        W  ++ + D        
Sbjct: 160  LLQKLFGPTGARVTSDGSILYLDLPSNMVGSFLMG--------WFGVVFKADIARVSEF- 210

Query: 430  VYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAYGIMQFLAVILAQFGLSI 609
            V  GL+TG+ G++++FS    +  + +AD             Y ++ FL  +       I
Sbjct: 211  VAIGLSTGYLGSLTTFSGWNQKMLDLSADGQ---------WVYAVLGFLLGLFLTSYSII 261

Query: 610  MGFHMGKQFLAVV-------DNYLPLVTKRIYK-VLELTSMILGVVLVVITCILIGVK-- 759
            +G    K F  ++       D +  L        ++ LT M+L +V ++    ++ VK  
Sbjct: 262  LGVETAKGFKWLLHRRASSEDKFHCLKVNTFQSHIVSLTLMLLLLVALLTASSILLVKEF 321

Query: 760  -KQGSWRSWTFSMLFAPFGALLRYYLSKF----LNNKVSNF---PLGTFTANXXXXXXXX 915
             K  S     F  L A  G  LR++L++     L     N    P GT  AN        
Sbjct: 322  DKGTSEAQLWFGCLVAAPGVWLRWFLARLNGRGLGKDSQNLRWVPFGTLIANVVAACVMA 381

Query: 916  XXXXXXRGKLPGGKGHIVTNTIALHVLEGLDDGFCGGLTTVSTFVVELFGLK----TLFS 1083
                  +          V       V   +  G  G L+TVSTF+ E   ++       +
Sbjct: 382  ALATLKKS---------VNTRTCNTVASSIQFGLLGCLSTVSTFMAEFNAMRESDYPWRA 432

Query: 1084 YRYGTISILVCFAGVVLILGSYNWSVG 1164
            Y Y + +I+V FA   +I     W +G
Sbjct: 433  YAYASFTIVVSFAIGTIIYSVPVWVIG 459


>Q9HW19|CRCB|CRCB_PSEAE (SP: Pseudomonas aeruginosa) Protein crcB
            homolog.
          Length = 127

 Score = 49.7 bits (117), Expect = 7e-05
 Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 7/138 (5%)
 Frame = +1

Query: 772  WRSWTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTAN---XXXXXXXXXXXXXXRGK 942
            W+S     L A  GALLR++L   LN+ + + P GT  AN                  G 
Sbjct: 2    WKSILAIALGAALGALLRWFLGLKLNSLLPSIPPGTLLANLVGGYVIGAAIAYFAQAPGI 61

Query: 943  LPGGKGHIVTNTIALHVLEGLDDGFCGGLTTVSTFVVELFGL--KTLFSYRYGTISILVC 1116
             P  +  I+T             GFCGGLTT STF  E+  L  +    +  G I+  V 
Sbjct: 62   APEWRLLIIT-------------GFCGGLTTFSTFSAEVVSLLQEGRLGWAAGAIATHVS 108

Query: 1117 FAGVVLILG--SYNWSVG 1164
             + ++ +LG  S NW +G
Sbjct: 109  GSLLMTLLGLFSMNWMLG 126


>Q8CS29|SE1451|Q8CS29 (TrEMBL: Staphylococcus epidermidis) Conserved
            hypothetical protein.
          Length = 121

 Score = 45.4 bits (106), Expect = 0.001
 Identities = 39/116 (33%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIALH 990
            GAL+R+ LS    N+ S  PLGTF AN                 L G  G +  +    H
Sbjct: 13   GALIRFCLSML--NEGSTIPLGTFVANLLGAF------------LMGSIGALSLSLFKTH 58

Query: 991  --VLEGLDDGFCGGLTTVSTFVVEL--------FGLKTLFSYRYGTISILVCFAGV 1128
              + +GL  G  G LTT STF  EL        F L T++      + IL C+ GV
Sbjct: 59   PNIKKGLTTGLLGALTTFSTFQFELVTLFNQHHFILFTIYGVTSYILGILSCYLGV 114


>Q8DPG7|CRCB|Q8DPG7 (TrEMBL: Streptococcus pneumoniae (strain ATCC
            BAA-255 / R6)) CrcB protein.
          Length = 109

 Score = 44.7 bits (104), Expect = 0.002
 Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
 Frame = +1

Query: 808  FGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIAL 987
            FGAL+RY+ S++  N+ S  PLGT  AN                      G    +  + 
Sbjct: 12   FGALVRYFFSRY--NQASKLPLGTLIANLLGCFLI---------------GVFYNHVESK 54

Query: 988  HVLEGLDDGFCGGLTTVSTFVVELFGL----KTLFSYRYGTI--SILVCFAGVVL 1134
             V   L  GFCGGLTT ST   EL  L    K  +SY   T    ++  F G++L
Sbjct: 55   EVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVAIFLGILL 109


>Q89Z03|CRCB|CRCB_BACTN (SP: Bacteroides thetaiotaomicron) Protein
            crcB homolog.
          Length = 124

 Score = 42.7 bits (99), Expect = 0.008
 Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVS-NFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIAL 987
            G +LRY +S+++ N ++ +FPLGT   N                     +G+++   + +
Sbjct: 15   GGVLRYLISRYVQNFLTPSFPLGTLLVNVLGCFAIGLFYGLFE------RGNLMNPNLRM 68

Query: 988  HVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISI-LVCFAGVVLILGSYN 1152
                 L  GFCGG TT STF+ E F L    ++ Y ++ + L  F G +++   Y+
Sbjct: 69   F----LTVGFCGGFTTFSTFMNENFQLIKDDNFFYLSLYVGLSLFVGFIMLYLGYS 120


>Q97QC5|SP1294|Q97QC5 (TrEMBL: Streptococcus pneumoniae) CrcB protein.
          Length = 109

 Score = 42.0 bits (97), Expect = 0.014
 Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 6/114 (5%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIALH 990
            GAL+RY+ S++  N+ S  PLGT  AN                      G    +  +  
Sbjct: 13   GALVRYFFSRY--NQASKLPLGTLIANLLGCFLI---------------GVFYNHVESKE 55

Query: 991  VLEGLDDGFCGGLTTVSTFVVELFGL----KTLFSYRYGTI--SILVCFAGVVL 1134
            V   L  GFCGGLTT ST   EL  L    K  +SY   T    ++  F G++L
Sbjct: 56   VYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVAIFLGILL 109


>Q8Y5I1|CRCB1|CRB1_LISMO (SP: Listeria monocytogenes) Protein crcB
            homolog 1.
          Length = 118

 Score = 41.2 bits (95), Expect = 0.024
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
 Frame = +1

Query: 802  APFGALLRYYLSKFLNNK-VSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNT 978
            A  GA+LRY +S  + +K  +NFP  TF  N                      G +V++ 
Sbjct: 12   AALGAMLRYGISVLVKSKWKTNFPSATFFINITGSFLL---------------GFLVSSA 56

Query: 979  IALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVLILG 1143
            +       L  GF GG TT STF VE   LK   +YR     +L  + G   + G
Sbjct: 57   LGPVWQLFLGTGFMGGYTTFSTFKVESMELKWKTNYR-----VLFSYLGFTYVFG 106


>Q8NW04|CRCB|CRCB_STAAW (SP: Staphylococcus aureus (strain MW2))
            Protein crcB homolog.
          Length = 147

 Score = 40.8 bits (94), Expect = 0.032
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
 Frame = +1

Query: 781  WTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKG 960
            + +  +    GALLRY +S FLN     FP+GT  AN                      G
Sbjct: 29   YVYIFIGGALGALLRYLIS-FLNTD-GGFPIGTLIANLTGAFVM---------------G 71

Query: 961  HIVTNTIALH-----VLEGLDDGFCGGLTTVSTFVVEL--------FGLKTLFSYRYGTI 1101
             +   TIA       + + +  GF G LTT STF +EL        F    L++      
Sbjct: 72   LLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTSYVF 131

Query: 1102 SILVCFAGVVL 1134
             IL+C+ G+ L
Sbjct: 132  GILLCYVGIKL 142


>Q99T86|CRCB|CRCB_STAAM (SP: Staphylococcus aureus (strain N315))
            Protein crcB homolog.
          Length = 147

 Score = 40.8 bits (94), Expect = 0.032
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
 Frame = +1

Query: 781  WTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKG 960
            + +  +    GALLRY +S FLN     FP+GT  AN                      G
Sbjct: 29   YVYIFIGGALGALLRYLIS-FLNTD-GGFPIGTLIANLTGAFVM---------------G 71

Query: 961  HIVTNTIALH-----VLEGLDDGFCGGLTTVSTFVVEL--------FGLKTLFSYRYGTI 1101
             +   TIA       + + +  GF G LTT STF +EL        F    L++      
Sbjct: 72   LLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTSYVF 131

Query: 1102 SILVCFAGVVL 1134
             IL+C+ G+ L
Sbjct: 132  GILLCYVGIKL 142


>Q929T7|CRCB1|CRB1_LISIN (SP: Listeria innocua) Protein crcB homolog
            1.
          Length = 118

 Score = 40.4 bits (93), Expect = 0.041
 Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 9/120 (7%)
 Frame = +1

Query: 802  APFGALLRYYLSKFLNNK-VSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNT 978
            A  GA+LRY +S F+ +K  ++FP  TF  N                      G +V+  
Sbjct: 12   ASLGAMLRYGISIFVKSKWKTDFPYATFFINITGSFLL---------------GFLVSTA 56

Query: 979  IALHVLEGLDDGFCGGLTTVSTFVVELFGLK------TLFSYRYGT--ISILVCFAGVVL 1134
            +       L  GF GG TT STF VE   LK       LFSY   T    ++  F G++L
Sbjct: 57   LGPMWQLFLGTGFMGGYTTFSTFKVESMELKWKANFQVLFSYVGLTYLCGLIAAFIGIML 116


>Q82U09|NE1704|Q82U09 (TrEMBL: Nitrosomonas europaea) CRCB protein.
          Length = 127

 Score = 40.0 bits (92), Expect = 0.054
 Identities = 34/122 (27%), Positives = 49/122 (40%)
 Frame = +1

Query: 772  WRSWTFSMLFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPG 951
            W+      L +  G LLR+ L   LNN   + P GT  AN                    
Sbjct: 2    WKPILAIALGSTLGGLLRWGLGLKLNNLFPDVPPGTLVANLIAGYVVGVAIAFF------ 55

Query: 952  GKGHIVTNTIALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVV 1131
               H+   +    +L  +  GFCGGL+T STF  E+  L     Y +   +I V  AG +
Sbjct: 56   --AHMPNLSPEWRLL--VITGFCGGLSTFSTFSAEIVSLLQRGLYAWAMSAIAVHVAGSL 111

Query: 1132 LI 1137
            ++
Sbjct: 112  IM 113


>Q8DPG6|CRCB|Q8DPG6 (TrEMBL: Streptococcus pneumoniae (strain ATCC
            BAA-255 / R6)) CrcB protein.
          Length = 124

 Score = 39.3 bits (90), Expect = 0.092
 Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
 Frame = +1

Query: 796  LFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTN 975
            L A  G L+RY +S +L     +FP GT   N                     KG++V  
Sbjct: 13   LAAMLGGLVRYLVSTWLPAS-PDFPWGTLFVNYLGIFCLIFLV----------KGYLVYK 61

Query: 976  TIALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVLI---LGS 1146
              +  ++  L  GFCGGLTT S+ +++   L     Y    + +L+   G +L+   LG 
Sbjct: 62   GTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLVLYLLLSIGGGLLLAYFLGR 121

Query: 1147 YNW 1155
              W
Sbjct: 122  KKW 124



 Score = 34.3 bits (77), Expect = 3.0
 Identities = 31/107 (28%), Positives = 50/107 (46%)
 Frame = +1

Query: 199 KTQKYYPVILNIVHGAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGEVF 378
           K +++YP  L I   A+ G LVR  +      S  F  G ++ N+     +   + G + 
Sbjct: 2   KKEQFYP--LGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNYLGIFCLIFLVKGYLV 59

Query: 379 WIRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADT 519
           +          +KG I     L TGFCG +++FSS++L+   K  DT
Sbjct: 60  Y-------KGTSKGLI---LALGTGFCGGLTTFSSLMLDTV-KLLDT 95


>Q97QC4|SP1295|Q97QC4 (TrEMBL: Streptococcus pneumoniae) CrcB protein.
          Length = 124

 Score = 39.3 bits (90), Expect = 0.092
 Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
 Frame = +1

Query: 796  LFAPFGALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTN 975
            L A  G L+RY +S +L     +FP GT   N                     KG++V  
Sbjct: 13   LAAMLGGLVRYLVSTWLPAS-PDFPWGTLFVNYLGIFCLIYLV----------KGYLVYK 61

Query: 976  TIALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVLI---LGS 1146
              +  ++  L  GFCGGLTT S+ +++   L     Y    + +L+   G +L+   LG 
Sbjct: 62   GTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLILYLLLSIGGGLLLAYYLGR 121

Query: 1147 YNW 1155
              W
Sbjct: 122  KKW 124



 Score = 34.7 bits (78), Expect = 2.3
 Identities = 37/145 (25%), Positives = 67/145 (46%)
 Frame = +1

Query: 199 KTQKYYPVILNIVHGAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGEVF 378
           K +++YP  L I   A+ G LVR  +      S  F  G ++ N+     +   + G + 
Sbjct: 2   KKEQFYP--LGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNYLGIFCLIYLVKGYLV 59

Query: 379 WIRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAY 558
           +          +KG I     L TGFCG +++FSS++L+   K  DT          G Y
Sbjct: 60  Y-------KGTSKGLI---LALGTGFCGGLTTFSSLMLDTV-KLLDT----------GRY 98

Query: 559 GIMQFLAVILAQFGLSIMGFHMGKQ 633
            +   L ++L+  G  ++ +++G++
Sbjct: 99  -LSLILYLLLSIGGGLLLAYYLGRK 122


>Q925U7||Q925U7 (TrEMBL: Mus musculus (Mouse)) Ileal
           sodium-dependent bile acid transporter.
          Length = 348

 Score = 38.5 bits (88), Expect = 0.16
 Identities = 44/209 (21%), Positives = 84/209 (40%), Gaps = 9/209 (4%)
 Frame = +1

Query: 241 GAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGE-----VFWIRLLEEKD 405
           G   G L + G+M LT +  S  SG++       ++MG    G       +WI       
Sbjct: 67  GIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWI------- 119

Query: 406 YPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAYGIMQFLAVI 585
               G + +   +TT  C T+ +   + L  F       +  +    +G       + + 
Sbjct: 120 ---DGDMDLSVSMTT--CSTLLALGMMPLCLF-------VYTKMWVDSGT------IVIP 161

Query: 586 LAQFGLSIMGFHMGKQFLAVVDNYLPLVTKRIYKVLELTSMILGVVLVVITCILIGVKKQ 765
               G+S++   +   F   V++  P   K I K+  +T    GV+L+V+  ++ G+  Q
Sbjct: 162 YDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSIT----GVILIVLIAVIGGILYQ 217

Query: 766 GSW----RSWTFSMLFAPFGALLRYYLSK 840
            +W    + W    +F   G  L ++L++
Sbjct: 218 SAWIIEPKLWIIGTIFPIAGYSLGFFLAR 246


>P70172|SLC10A2|P70172 (TrEMBL: Mus musculus (Mouse)) Ileal
           NA+-dependent bile acid transporter (ISBT).
          Length = 348

 Score = 38.5 bits (88), Expect = 0.16
 Identities = 44/209 (21%), Positives = 84/209 (40%), Gaps = 9/209 (4%)
 Frame = +1

Query: 241 GAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGE-----VFWIRLLEEKD 405
           G   G L + G+M LT +  S  SG++       ++MG    G       +WI       
Sbjct: 67  GIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWI------- 119

Query: 406 YPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAYGIMQFLAVI 585
               G + +   +TT  C T+ +   + L  F       +  +    +G       + + 
Sbjct: 120 ---DGDMDLSVSMTT--CSTLLALGMMPLCLF-------VYTKMWVDSGT------IVIP 161

Query: 586 LAQFGLSIMGFHMGKQFLAVVDNYLPLVTKRIYKVLELTSMILGVVLVVITCILIGVKKQ 765
               G+S++   +   F   V++  P   K I K+  +T    GV+L+V+  ++ G+  Q
Sbjct: 162 YDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSIT----GVILIVLIAVIGGILYQ 217

Query: 766 GSW----RSWTFSMLFAPFGALLRYYLSK 840
            +W    + W    +F   G  L ++L++
Sbjct: 218 SAWIIEPKLWIIGTIFPIAGYSLGFFLAR 246


>P46491|CRCB|CRCB_HAEIN (SP: Haemophilus influenzae) Protein crcB
           homolog.
          Length = 160

 Score = 36.2 bits (82), Expect = 0.78
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 4/97 (4%)
 Frame = +1

Query: 223 ILNIVHGAIWGVLVRKGL-MLLTTYSGSFLSGVIWANFAACVVMGLAIDGEVFWIRLLEE 399
           +L I +GAI G  +R  + +L      SF  G + AN   C+++G+ +   +FW      
Sbjct: 4   LLFISYGAILGASLRWAIGLLFNPLFSSFAFGTLIANLFGCLIIGVLLG--LFW------ 55

Query: 400 KDYPNKGAIPVYTGLTTGFCGTV---SSFSSVILEAF 501
             +P   A      L TGF G++   SSFSS ++E F
Sbjct: 56  -QFPQISA-EWRLFLITGFLGSLTTFSSFSSEVVELF 90


>Q8TJ54|CRCB1|CRB1_METAC (SP: Methanosarcina acetivorans) Protein crcB
            homolog 1.
          Length = 131

 Score = 36.2 bits (82), Expect = 0.78
 Identities = 30/86 (34%), Positives = 35/86 (40%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIALH 990
            GA+LRY LS ++ N   NFPLGT   N                 L   +G     T  L 
Sbjct: 14   GAVLRYSLSGWVQNSFVNFPLGTLVVNIVGSFFLGLVMY-----LSEYQGLFSEETRIL- 67

Query: 991  VLEGLDDGFCGGLTTVSTFVVELFGL 1068
                L  G  G  TT+STF  E F L
Sbjct: 68   ----LTIGLLGAFTTLSTFSYESFRL 89


>Q9FC37|CRCB2|CRB2_STRCO (SP: Streptomyces coelicolor) Protein crcB
            homolog 2.
          Length = 124

 Score = 35.8 bits (81), Expect = 1.0
 Identities = 31/128 (24%), Positives = 46/128 (35%), Gaps = 9/128 (7%)
 Frame = +1

Query: 778  SWTFSMLFAPFGALLRYYLSKFLNNKVSN-FPLGTFTANXXXXXXXXXXXXXXRGKLPGG 954
            +W   +     GA LRY   + + ++  + FP GTFT N                   G 
Sbjct: 2    NWLLVVAGGMIGAPLRYLTDRAVQSRHDSVFPWGTFTVNVIGSVVLGLLTGAALAGAVGS 61

Query: 955  KGHIVTNTIALHVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISI--------L 1110
               ++  T           G CG LTT STF  E   L    +  +  +++        +
Sbjct: 62   DLRLLLGT-----------GLCGALTTYSTFSYETLRLTETGARLHAAVNVGGSVAAGLV 110

Query: 1111 VCFAGVVL 1134
              FAGV L
Sbjct: 111  AAFAGVTL 118


>Q9CKI7|CRCB|CRCB_PASMU (SP: Pasteurella multocida) Protein crcB
           homolog.
          Length = 128

 Score = 35.8 bits (81), Expect = 1.0
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = +1

Query: 223 ILNIVHGAIWGVLVRKGL-MLLTTYSGSFLSGVIWANFAACVVMGLAIDGEVFWIRLLEE 399
           I+ I  GA  G L R GL +LL     +F  G + AN+  C+++G+ +    FW      
Sbjct: 8   IIFISSGAALGALSRWGLGLLLNPLFSAFSLGTLVANYLGCLIIGVFL--AFFW------ 59

Query: 400 KDYPNKGAIPVYTGLTTGFCGTVSSFSSVILE 495
             YP   A        TGF G++++FS+   E
Sbjct: 60  -QYPQCSA-EWRLFFVTGFLGSLTTFSTFSAE 89


>Q815R5|BC5068|Q815R5 (TrEMBL: Bacillus cereus (strain ATCC 14579 /
            DSM 31)) CrcB family protein.
          Length = 118

 Score = 35.4 bits (80), Expect = 1.3
 Identities = 33/119 (27%), Positives = 45/119 (37%), Gaps = 7/119 (5%)
 Frame = +1

Query: 808  FGALLRYYLSK-FLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIA 984
            FGA+ R+ +S  F     + FPL TF  N                      G+I+ N + 
Sbjct: 13   FGAITRFAISNWFKKRNKTQFPLATFLINITGAFLL---------------GYIIGNGVT 57

Query: 985  LHVLEGLDDGFCGGLTTVSTFVVELF------GLKTLFSYRYGTISILVCFAGVVLILG 1143
                  L  GF G  TT STF +E         + T   Y   T  I + FA + + LG
Sbjct: 58   TGWQLLLGTGFMGAFTTFSTFKLEAVQLLNRKNISTFLLYLSATYIIGILFAFLGMKLG 116


>Q97IQ3|CRCB1|CRB1_CLOAB (SP: Clostridium acetobutylicum) Protein crcB
            homolog 1.
          Length = 117

 Score = 35.4 bits (80), Expect = 1.3
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKV-SNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIAL 987
            G+++RY +   ++ +  S FP GTF  N               GK               
Sbjct: 13   GSIVRYKIGDIISKRTKSKFPWGTFIINITGAFLLGIITKSGAGK--------------- 57

Query: 988  HVLEGLDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAGVVL-ILGSY 1149
            ++   L DGF G  TT STF+ E F    LF  +    +++   + +++ ILG Y
Sbjct: 58   NLSMILADGFLGAYTTFSTFMYEGF---NLFENKKKLNALIYILSSIIIGILGFY 109


>P43129|FRE|FRE_PHOLU (SP: Photorhabdus luminescens (Xenorhabdus
           luminescens)) NAD(P)H-flavin reductase (EC 1.6.8.-)
           (NAD(P)H:flavin oxidoreductase).
          Length = 232

 Score = 35.4 bits (80), Expect = 1.3
 Identities = 19/48 (39%), Positives = 25/48 (52%)
 Frame = +1

Query: 382 IRLLEEKDYPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDI 525
           +RLL E+ YPN   IPV      G+CG   +    +LE F   A+ DI
Sbjct: 151 LRLLTER-YPNLKVIPVVEQSDNGWCGRTGTVLKAVLEDFGSLANYDI 197


>Q8XGH9|CRCB|CRCB_SALTY (SP: Salmonella typhi) Protein crcB homolog.
          Length = 127

 Score = 35.0 bits (79), Expect = 1.7
 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIALH 990
            G++ R+ LS   N      P+GT TAN               G    G G    N +  H
Sbjct: 15   GSVARWMLSMRFNPLHQAIPIGTLTANLL-------------GAFIIGMGFAWFNRMT-H 60

Query: 991  VLEG----LDDGFCGGLTTVSTFVVELFGLKTLFSYRYGTISILVCFAG 1125
            +       +  GFCGGLTT STF  E+  L     + +  +++L+   G
Sbjct: 61   IDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLG 109


>Q8TW26|CRCB|CRCB_METKA (SP: Methanopyrus kandleri) Protein crcB
            homolog.
          Length = 131

 Score = 35.0 bits (79), Expect = 1.7
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
 Frame = +1

Query: 811  GALLRYYLSKFLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIALH 990
            GA+ RY LS  +  +V  FP+GT   N                 L      +     AL 
Sbjct: 19   GAVCRYLLSGLVP-QVRGFPMGTVLVNVLGSFVLGFLTWSTMLGL-----RLSPEVRALA 72

Query: 991  VLEGLDDGFCGGLTTVSTF---VVELFGLKTLFSYRYGTISILVCFAGVVLILG 1143
             +     GFCGGLTT+ST     VEL     + S  Y T ++++   G+  +LG
Sbjct: 73   TV-----GFCGGLTTLSTMAYETVELLKASPVLSILYLTANVVL---GIAAVLG 118


>Q8RYS0|OSJNBA0026J14.14|Q8RYS0 (TrEMBL: Oryza sativa (japonica
           cultivar-group)) Nodulin-like protein.
          Length = 318

 Score = 34.3 bits (77), Expect = 3.0
 Identities = 24/101 (23%), Positives = 42/101 (41%)
 Frame = +1

Query: 556 YGIMQFLAVILAQFGLSIMGFHMGKQFLAVVDNYLPLVTKRIYKVLELTSMILGVVLVVI 735
           +GI +   V+ +  G+ I+ F+ G +  ++  N   L ++ +      T           
Sbjct: 97  HGIAKVFGVLFSIVGVIILAFYQGPELKSL--NLQHLSSRNVVP----TGSTAYTTKAWT 150

Query: 736 TCILIGVKKQGSWRSWTFSMLFAPFGALLRYYLSKFLNNKV 858
           + I + V    SW  WT   +  P G +L  Y SK LN  +
Sbjct: 151 SGIFLTVLSTTSWALWTVLQIVLPQGLMLEVYPSKLLNTTI 191


>Q81XC0|BA5320|Q81XC0 (TrEMBL: Bacillus anthracis (strain Ames)) CrcB
            protein.
          Length = 118

 Score = 34.3 bits (77), Expect = 3.0
 Identities = 32/119 (26%), Positives = 46/119 (38%), Gaps = 7/119 (5%)
 Frame = +1

Query: 808  FGALLRYYLSK-FLNNKVSNFPLGTFTANXXXXXXXXXXXXXXRGKLPGGKGHIVTNTIA 984
            FGA+ R+ +S  F     ++FP+ TF  N                      G+I+ N + 
Sbjct: 13   FGAITRFTISNWFKKRNKTSFPIATFLINITGAFLL---------------GYIIGNGVT 57

Query: 985  LHVLEGLDDGFCGGLTTVSTFVVELFGL------KTLFSYRYGTISILVCFAGVVLILG 1143
                  L  GF G  TT STF +E   L       T   Y   T  + + FA + + LG
Sbjct: 58   TGWQLLLGTGFMGAFTTFSTFKLESVQLLNRKNFSTFLLYLSATYIVGILFAFLGMKLG 116


>Q62633|SLC10A2|NTCI_RAT (SP: Rattus norvegicus (Rat)) Ileal
           sodium/bile acid cotransporter (Ileal Na(+)/bile acid
           cotransporter) (Na+ dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (Sodium/taurocholate cotransporting
           polypeptide, ileal).
          Length = 348

 Score = 34.3 bits (77), Expect = 3.0
 Identities = 43/209 (20%), Positives = 81/209 (38%), Gaps = 9/209 (4%)
 Frame = +1

Query: 241 GAIWGVLVRKGLMLLTTYSGSFLSGVIWANFAACVVMGLAIDGE-----VFWIRLLEEKD 405
           G   G L + G+M LT +  S  SG++       ++MG    G       +WI       
Sbjct: 67  GIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWI------- 119

Query: 406 YPNKGAIPVYTGLTTGFCGTVSSFSSVILEAFNKAADTDIGVRHHYPNGAYGIMQFLAVI 585
               G + +   +TT  C T+ +   + L  F       I  +    +G       + + 
Sbjct: 120 ---DGDMDLSVSMTT--CSTLLALGMMPLCLF-------IYTKMWVDSGT------IVIP 161

Query: 586 LAQFGLSIMGFHMGKQFLAVVDNYLPLVTKRIYKVLELTSMILGVVLVVITCILIGVKKQ 765
               G+S++   +       V++  P   K I K+      I G +L+V+  ++ G+  Q
Sbjct: 162 YDSIGISLVALVIPVSIGMFVNHKWPQKAKIILKI----GSIAGAILIVLIAVVGGILYQ 217

Query: 766 GSW----RSWTFSMLFAPFGALLRYYLSK 840
            +W    + W    +F   G  L ++L++
Sbjct: 218 SAWIIEPKLWIIGTIFPIAGYSLGFFLAR 246


  Database: sptrembl
    Posted date:  Oct 14, 2003  6:47 PM
  Number of letters in database: 339,323,595
  Number of sequences in database:  1,070,300
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 379,917,013
Number of Sequences: 1070300
Number of extensions: 8679837
Number of successful extensions: 33922
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33071
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33891
length of database: 339,323,595
effective HSP length: 123
effective length of database: 207,676,695
effective search space used: 55242000870
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)