BLASTX 2.2.6 [Apr-09-2003]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Candida_albicans_chr7-f3-156150-157241-5
         (1089 letters)

Database: sptrembl 
           1,070,300 sequences; 339,323,595 total letters

Searching.................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

P40348|RFC2|RFC2_YEAST (SP: Saccharomyces cerevisiae (Baker's ye...   407   e-112
Q09843|RCF2|RFC2_SCHPO (SP: Schizosaccharomyces pombe (Fission y...   358   6e-98
Q99J62|AU040575|Q99J62 (TrEMBL: Mus musculus (Mouse)) Similar to...   304   1e-81
P35249|RFC4|RFC4_HUMAN (SP: Homo sapiens (Human)) Activator 1 37...   302   4e-81
Q9FXM3|OSRFC37|Q9FXM3 (TrEMBL: Oryza sativa (Rice)) Replication ...   300   2e-80
Q93ZX1|F8K7.11|Q93ZX1 (TrEMBL: Arabidopsis thaliana (Mouse-ear c...   298   8e-80
Q86EA0||Q86EA0 (TrEMBL: Schistosoma japonicum (Blood fluke)) Clo...   290   2e-77
Q9XI09|F8K7.11|Q9XI09 (TrEMBL: Arabidopsis thaliana (Mouse-ear c...   280   2e-74
Q9VX15|CG8142|Q9VX15 (TrEMBL: Drosophila melanogaster (Fruit fly...   265   5e-70
Q8QNA5||Q8QNA5 (TrEMBL: Ectocarpus siliculosus virus) EsV-1-182.      259   4e-68
Q9GR07|RFC2|Q9GR07 (TrEMBL: Plasmodium falciparum) Replication f...   245   8e-64
O96260|PFB0840W|O96260 (TrEMBL: Plasmodium falciparum) Replicati...   242   6e-63
Q9YBS7|APE1522|Q9YBS7 (TrEMBL: Aeropyrum pernix) 346AA long hypo...   227   2e-58
O28219|AF2060|O28219 (TrEMBL: Archaeoglobus fulgidus) Activator ...   223   2e-57
Q8ZYK4|PAE0734|Q8ZYK4 (TrEMBL: Pyrobaculum aerophilum) Replicati...   217   2e-55
Q975D3|ST0475|Q975D3 (TrEMBL: Sulfolobus tokodaii) Putative repl...   217   2e-55
Q8PVY4|MM1821|Q8PVY4 (TrEMBL: Methanosarcina mazei (Methanosarci...   213   2e-54
Q9UXF5|RFC|Q9UXF5 (TrEMBL: Sulfolobus solfataricus) Activator 1,...   211   9e-54
P53016|F31E3.3|RFC4_CAEEL (SP: Caenorhabditis elegans) Putative ...   210   3e-53
Q8TSX5|RFCS|Q8TSX5 (TrEMBL: Methanosarcina acetivorans) Replicat...   209   5e-53
Q9VKW3|RFC3|Q9VKW3 (TrEMBL: Drosophila melanogaster (Fruit fly))...   207   1e-52
Q8ZWS2|PAE1646|Q8ZWS2 (TrEMBL: Pyrobaculum aerophilum) Replicati...   200   2e-50
P34429|F44B9.8|RFC5_CAEEL (SP: Caenorhabditis elegans) Putative ...   199   5e-50
Q8IKK4|PF14_0601|Q8IKK4 (TrEMBL: Plasmodium falciparum (isolate ...   198   1e-49
Q9GR09|RFC3|Q9GR09 (TrEMBL: Plasmodium falciparum) Replication f...   198   1e-49
O26343|MTH241|O26343 (TrEMBL: Methanobacterium thermoautotrophic...   197   2e-49
P40937|RFC5|RFC5_HUMAN (SP: Homo sapiens (Human)) Activator 1 36...   197   2e-49
Q872Q7|B13B3.180|Q872Q7 (TrEMBL: Neurospora crassa) Related to r...   196   5e-49
O14003|RFC3|RFC3_SCHPO (SP: Schizosaccharomyces pombe (Fission y...   196   5e-49
O74111|RFC3|RFC3_ARXAD (SP: Arxula adeninivorans (Yeast)) Activa...   195   7e-49

>P40348|RFC2|RFC2_YEAST (SP: Saccharomyces cerevisiae (Baker's yeast))
            Activator 1 41 kDa subunit (Replication factor C subunit
            2) (Replication factor C2).
          Length = 353

 Score =  407 bits (1046), Expect = e-112
 Identities = 206/358 (57%), Positives = 273/358 (76%)
 Frame = +1

Query: 13   GTTIRKQKNQAYEEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYG 192
            G   +++ ++   E+ L   PWVEKYRPK+L++V++Q+H + VL +T+KS NLPHMLFYG
Sbjct: 6    GPNKKRKISKLAAEQSLAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLFYG 65

Query: 193  PPGTGKTSTILALAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKED 372
            PPGTGKTSTILAL KELYGP+L KSR+LELNASDERGISIVREK+KNFARLT+S P+K D
Sbjct: 66   PPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARLTVSKPSKHD 125

Query: 373  LQNYPCPPYKIIILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCS 552
            L+NYPCPPYKIIILDEADSMT DAQSALRRTME Y+G+TRF LICNY+TRIIDP+ SRCS
Sbjct: 126  LENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPLASRCS 185

Query: 553  KFRFKLLNNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAK 732
            KFRFK L+  NA  RL++I +QEN++ +       V++ +L IS GDLR+ IT LQSA+K
Sbjct: 186  KFRFKALDASNAIDRLRFISEQENVKCDD-----GVLERILDISAGDLRRGITLLQSASK 240

Query: 733  LSETFDINHHQSLITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGW 912
             ++      +   IT   + E AG++P DIL E+++  K+K+     IK    + + SGW
Sbjct: 241  GAQYLGDGKN---ITSTQVEELAGVVPHDILIEIVE--KVKSGDFDEIKKYVNTFMKSGW 295

Query: 913  SAQILLDQLHDKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQV 1086
            SA  +++QLH+  I +++ ++  KN+IS + F  D +LNNGT+EHIQLLN+L++ISQ+
Sbjct: 296  SAASVVNQLHEYYITNDNFDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL 353


>Q09843|RCF2|RFC2_SCHPO (SP: Schizosaccharomyces pombe (Fission
            yeast)) Probable activator 1 subunit 2 (Replication
            factor C subunit 2) (Replication factor C2).
          Length = 340

 Score =  358 bits (919), Expect = 6e-98
 Identities = 190/351 (54%), Positives = 253/351 (72%)
 Frame = +1

Query: 34   KNQAYEEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKT 213
            +N+  E+E     PWVE YRPK+L+ VSSQE T++VL +T+ S NLPHMLFYG PGTGKT
Sbjct: 7    RNKKTEQEAKKSIPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKT 66

Query: 214  STILALAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCP 393
            STILAL++EL+GP L KSRVLELNASDERGISI+REK+K+FA+ T++N     +  YPCP
Sbjct: 67   STILALSRELFGPQLMKSRVLELNASDERGISIIREKVKSFAKTTVTN----KVDGYPCP 122

Query: 394  PYKIIILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLL 573
            P+KIIILDEADSMT DAQ+ALRRTME+YA ITRF LICNY+TRIIDP++SRCSK+RFK L
Sbjct: 123  PFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPL 182

Query: 574  NNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDI 753
            +NEN   RL++I   + +  E       V+  L++ SGGD+RKAIT+LQSAA L      
Sbjct: 183  DNENMVKRLEFIAADQAVSMEP-----GVVNALVECSGGDMRKAITFLQSAANL------ 231

Query: 754  NHHQSLITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLD 933
             H  + ITI S+ E AG +P +I+  L+     K   +  I+ + + +   G+S  I+L 
Sbjct: 232  -HQGTPITISSVEELAGAVPYNIIRSLLDTAYTKNVSN--IETLSRDVAAEGYSTGIILS 288

Query: 934  QLHDKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQV 1086
            QLHD L+ +E+++S +K KI     ++D++LN+G DE +QLL++L  IS V
Sbjct: 289  QLHDVLLKEETLSSPVKYKIFMKLSEVDKRLNDGADETLQLLDLLSSISVV 339


>Q99J62|AU040575|Q99J62 (TrEMBL: Mus musculus (Mouse)) Similar to
            replication factor C (Activator 1) 4 (37kD).
          Length = 364

 Score =  304 bits (778), Expect = 1e-81
 Identities = 162/347 (46%), Positives = 242/347 (69%)
 Frame = +1

Query: 49   EEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILA 228
            E +K+   PWVEKYRPK +++V+ Q+  + VL ++++  +LP++LFYGPPGTGKTSTILA
Sbjct: 31   ETKKVKPVPWVEKYRPKCVDEVAFQDEVVAVLRKSLEGADLPNLLFYGPPGTGKTSTILA 90

Query: 229  LAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKII 408
             A+EL+GP L++ RVLELNASDERGI +VREK+KNFA+LT+S    +     PCPP+KI+
Sbjct: 91   AARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSD---GKPCPPFKIV 147

Query: 409  ILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENA 588
            ILDEADSMT+ AQ+ALRRTME  +  TRF LICNY++RII+P+TSRCSKFRFK L+++  
Sbjct: 148  ILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQ 207

Query: 589  QLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQS 768
            Q RL  I ++EN++  +E      I  L+KIS GDLRKAIT+LQSA +L+   +++    
Sbjct: 208  QERLLDIAEKENVKIGNEE-----IAYLVKISEGDLRKAITFLQSATRLTGGKEVSE--- 259

Query: 769  LITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDK 948
                  I + AG++P   +  +  F    +     ++ + +++I  G +A  L++QLHD 
Sbjct: 260  ----DVITDIAGVIPAATIDGI--FTACHSGSFDKLEAVVKNLIDEGHAATQLVNQLHDA 313

Query: 949  LILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
            +I +E+++   K+ I++   ++D+ L +G DEH+QL+++   + Q L
Sbjct: 314  IIENENLSDKHKSIITEKLAEVDKCLADGADEHLQLMSLCATVMQQL 360


>P35249|RFC4|RFC4_HUMAN (SP: Homo sapiens (Human)) Activator 1 37 kDa
            subunit (Replication factor C 37 kDa subunit) (A1 37 kDa
            subunit) (RF-C 37 kDa subunit) (RFC37).
          Length = 363

 Score =  302 bits (774), Expect = 4e-81
 Identities = 165/349 (47%), Positives = 241/349 (69%), Gaps = 2/349 (0%)
 Frame = +1

Query: 49   EEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILA 228
            E +K    PWVEKYRPK +++V+ QE  + VL ++++  +LP++LFYGPPGTGKTSTILA
Sbjct: 31   ENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILA 90

Query: 229  LAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKII 408
             A+EL+GP L++ RVLELNASDERGI +VREK+KNFA+LT+S    +     PCPP+KI+
Sbjct: 91   AARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSD---GKPCPPFKIV 147

Query: 409  ILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENA 588
            ILDEADSMT+ AQ+ALRRTME  +  TRF LICNY++RII+P+TSRCSKFRFK L+++  
Sbjct: 148  ILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQ 207

Query: 589  QLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQS 768
            Q RL  I ++EN++   E      I  L+K+S GDLRKAIT+LQSA +L+   +      
Sbjct: 208  QQRLLDIAKKENVKISDEG-----IAYLVKVSEGDLRKAITFLQSATRLTGGKE------ 256

Query: 769  LITIQSIRETAGILPDDILAELIQFIKLKTQQSRL--IKYIDQSIILSGWSAQILLDQLH 942
             IT + I + AG++P    AE I  +    Q      ++ + + +I  G +A  L++QLH
Sbjct: 257  -ITEKVITDIAGVIP----AEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLH 311

Query: 943  DKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
            D ++++ +++   K+ I++   ++D+ L +G DEH+QL+++   + Q L
Sbjct: 312  D-VVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQL 359


>Q9FXM3|OSRFC37|Q9FXM3 (TrEMBL: Oryza sativa (Rice)) Replication
            factor C 37kDa subunit.
          Length = 339

 Score =  300 bits (768), Expect = 2e-80
 Identities = 162/339 (47%), Positives = 224/339 (66%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRP+ + DV+ QE  ++VLT T+++ +LPHMLFYGPPGTGKT+T LA+A +LYGP
Sbjct: 10   PWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLYGP 69

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
             LYKSRVLELNASD+RGI++VR KIK+FA + + +  K     YPCPPYKIIILDEADSM
Sbjct: 70   ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSARK---GGYPCPPYKIIILDEADSM 126

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T DAQ+ALRRTME Y+ +TRF  ICNYI+RII+P+ SRC+KFRFK L+ E    R+ +I 
Sbjct: 127  TEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHIC 186

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
             +E L  ++     Q +  L  IS GDLR+AITYLQSAA+L          S I+   + 
Sbjct: 187  NEEGLSLDA-----QALATLSTISNGDLRRAITYLQSAARL--------FGSSISSTDLI 233

Query: 793  ETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESIN 972
              +G +P+D++  L+     K+ +  +      +II  G+    L+ Q  D ++  + I 
Sbjct: 234  SVSGAIPEDVVKSLL--ASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIVNADDIP 291

Query: 973  SLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
               K +I +   + D+ L +G DE++QLL+V  +  + L
Sbjct: 292  DEQKARICKKLGEADKCLVDGADEYLQLLDVASETIRAL 330


>Q93ZX1|F8K7.11|Q93ZX1 (TrEMBL: Arabidopsis thaliana (Mouse-ear
            cress)) Putative replication factor C subunit (Similar
            replication factor C, 37-kDa subunit).
          Length = 339

 Score =  298 bits (763), Expect = 8e-80
 Identities = 159/332 (47%), Positives = 222/332 (66%), Gaps = 1/332 (0%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRPK + DV+ QE  ++VLT T+++ + PHMLFYGPPGTGKT+T LA+A +L+GP
Sbjct: 10   PWVEKYRPKQVKDVAHQEEVVRVLTNTLQTADCPHMLFYGPPGTGKTTTALAIAHQLFGP 69

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
             LYKSRVLELNASD+RGI++VR KIK+FA + + +  ++    YPCP +KIIILDEADSM
Sbjct: 70   ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSNHRQ--SGYPCPSFKIIILDEADSM 127

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T DAQ+ALRRTME Y+ +TRF  ICNYI+RII+P+ SRC+KFRFK L+ E    R+ +I 
Sbjct: 128  TEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHIC 187

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
             +E L  + E      +  L  IS GDLR+AITYLQSA +L          S IT   + 
Sbjct: 188  NEEGLSLDGE-----ALSTLSSISQGDLRRAITYLQSATRL--------FGSTITSTDLL 234

Query: 793  ETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLI-LDESI 969
              +G++P +++ +L  F   K+    +      +I+  G+ A  +++QL D +   D  I
Sbjct: 235  NVSGVVPLEVVNKL--FTACKSGDFDIANKEVDNIVAEGYPASQIINQLFDIVAEADSDI 292

Query: 970  NSLLKNKISQIFFQLDRKLNNGTDEHIQLLNV 1065
              + K KI +   + D++L +G DE++QLL+V
Sbjct: 293  TDMQKAKICKCLAETDKRLVDGADEYLQLLDV 324


>Q86EA0||Q86EA0 (TrEMBL: Schistosoma japonicum (Blood fluke)) Clone
            ZZD636 mRNA sequence.
          Length = 364

 Score =  290 bits (742), Expect = 2e-77
 Identities = 161/341 (47%), Positives = 224/341 (65%), Gaps = 8/341 (2%)
 Frame = +1

Query: 67   HTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELY 246
            H PWVEKYRPK++++V+ Q   + VL + I   +LP++LFYGPPGTGKTS ILALA++L+
Sbjct: 24   HIPWVEKYRPKTIDEVAYQTEVVSVLRRCIGGSDLPNLLFYGPPGTGKTSLILALARQLF 83

Query: 247  GPNLYKSRVLELNASDERGISIVREKIKNFARLTIS----NPTKEDLQNYPCPPYKIIIL 414
            GP LY  RVLELNASDERGI ++REK+K FA + +S    N       +   PPYK+IIL
Sbjct: 84   GP-LYSERVLELNASDERGIVVIREKVKAFAHVAVSSSGSNTNSSGSSSTNIPPYKLIIL 142

Query: 415  DEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQL 594
            DEADSMT  AQ+ALRRTME     TRF L CNY+TRII+PITSRC+KFRF+ L+NE A+ 
Sbjct: 143  DEADSMTAPAQAALRRTMETEMRTTRFCLTCNYVTRIIEPITSRCAKFRFRPLDNEIARA 202

Query: 595  RLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSL- 771
            RL+YI   ENL    E  +H     LL +  GDLR+ IT LQ   +L  + D ++  SL 
Sbjct: 203  RLRYIADAENLSVTDETLDH-----LLSLCRGDLRQGITMLQCVHQLIMSVDDSNSNSLS 257

Query: 772  ITIQSIRETAGILPDDILAELIQFIKLKTQQSRL---IKYIDQSIILSGWSAQILLDQLH 942
            IT   + E A ++P D++  L+     KT ++     ++ I ++++L G+SA   + QLH
Sbjct: 258  ITSSELDEAAAVVPTDVIKSLV-----KTSENGNFDDLQVIIKNLLLEGYSAHQTIYQLH 312

Query: 943  DKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNV 1065
            + +I DE+++ + K  I +     D +L +G DE++QLL +
Sbjct: 313  EYIINDETLSCIQKASILESLALADSRLIDGADEYLQLLAI 353


>Q9XI09|F8K7.11|Q9XI09 (TrEMBL: Arabidopsis thaliana (Mouse-ear
            cress)) F8K7.11 protein.
          Length = 319

 Score =  280 bits (716), Expect = 2e-74
 Identities = 152/332 (45%), Positives = 212/332 (63%), Gaps = 1/332 (0%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRPK + DV+ QE  ++VLT T+++ + PHMLFYGPPGTGKT+T LA+A +L+GP
Sbjct: 10   PWVEKYRPKQVKDVAHQEEVVRVLTNTLQTADCPHMLFYGPPGTGKTTTALAIAHQLFGP 69

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
             LYKSRVLELNASD+RGI++VR KIK+FA + + +  ++    YPCP +KIIILDEADSM
Sbjct: 70   ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSNHRQ--SGYPCPSFKIIILDEADSM 127

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T DAQ+ALRRTME Y+ +TRF  ICNYI+RII+P+ SRC+KFRFK L+ E    R+ +I 
Sbjct: 128  TEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHIC 187

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
             +E L  + E      +  L  IS GDLR+AITYLQ                        
Sbjct: 188  NEEGLSLDGE-----ALSTLSSISQGDLRRAITYLQ------------------------ 218

Query: 793  ETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLI-LDESI 969
                ++P +++ +L  F   K+    +      +I+  G+ A  +++QL D +   D  I
Sbjct: 219  ----VVPLEVVNKL--FTACKSGDFDIANKEVDNIVAEGYPASQIINQLFDIVAEADSDI 272

Query: 970  NSLLKNKISQIFFQLDRKLNNGTDEHIQLLNV 1065
              + K KI +   + D++L +G DE++QLL+V
Sbjct: 273  TDMQKAKICKCLAETDKRLVDGADEYLQLLDV 304


>Q9VX15|CG8142|Q9VX15 (TrEMBL: Drosophila melanogaster (Fruit fly))
            CG8142 protein (LD35209p).
          Length = 353

 Score =  265 bits (678), Expect = 5e-70
 Identities = 145/331 (43%), Positives = 218/331 (65%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRP++++DV  Q   + VL + ++ G+LP+ML YGPPGTGKTSTILA +++++G 
Sbjct: 31   PWVEKYRPRNVDDVVEQSEVVAVLRKCVEGGDLPNMLLYGPPGTGKTSTILAASRQIFG- 89

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
            +++K R+LELNASDERGI++VR KIKNF++L+ S+   +     PCPP+KIIILDEADSM
Sbjct: 90   DMFKDRILELNASDERGINVVRTKIKNFSQLSASSVRPD---GKPCPPFKIIILDEADSM 146

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T+ AQSALRRTME  +  TRF LICNY++RII PITSRCSKFRFK L  +    RLKYI 
Sbjct: 147  THAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRCSKFRFKALGEDKVIDRLKYIC 206

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
            + E ++ E +       + ++KISGGDLR+AIT LQS  +L         + +I    + 
Sbjct: 207  EMEGVKIEDD-----AYKSIVKISGGDLRRAITTLQSCYRLKGP------EHIINTADLF 255

Query: 793  ETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESIN 972
            E +G++P+  L + ++  +      RL +++ + I  S +S   +++Q  + ++    +N
Sbjct: 256  EMSGVIPEYYLEDYLEVCR-SGNYERLEQFV-REIGFSAYSVGQMMEQFVEFIVHHPGLN 313

Query: 973  SLLKNKISQIFFQLDRKLNNGTDEHIQLLNV 1065
               K  I     +   +L +G  E++Q++++
Sbjct: 314  DPQKATICDKLGECCFRLQDGGSEYLQIMDL 344


>Q8QNA5||Q8QNA5 (TrEMBL: Ectocarpus siliculosus virus) EsV-1-182.
          Length = 326

 Score =  259 bits (662), Expect = 4e-68
 Identities = 141/334 (42%), Positives = 211/334 (63%), Gaps = 3/334 (0%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRP+ + DV   +H  +VL    K+G+LPH+LF+GPPGTGKTSTILALA+ L G 
Sbjct: 3    PWVEKYRPRRVRDVVHHDHLKRVLNGAEKTGDLPHLLFHGPPGTGKTSTILALARTLLGE 62

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
               + RVLELNASDERG+ +VR+KIK F++++IS+          CPP+K++ILDEAD+M
Sbjct: 63   GNMRERVLELNASDERGLDVVRDKIKTFSKMSISS------FQPGCPPFKLVILDEADTM 116

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T DAQSALRRTME ++ +TRF L+CNY+++II P+ SRC+KFRF  L  ++ + RL +I 
Sbjct: 117  TADAQSALRRTMETHSVVTRFCLVCNYVSKIIAPLASRCAKFRFSTLAPKSMKGRLLHIC 176

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
            ++EN+ F  EN    V+  ++K S GD+R A+  LQ+ ++          Q  +T +SI 
Sbjct: 177  ERENIIF--ENCSRSVLDAIVKSSRGDMRSAVNLLQTVSQ----------QPRVTPESIV 224

Query: 793  ETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSI---ILSGWSAQILLDQLHDKLILDE 963
            E AG +P+ +   L   +  + +Q    + +  ++   +  G+    +L ++  +++   
Sbjct: 225  EIAGEVPERVFDMLWSAVTSQPRQPGHFEAVTDAVSTFVGEGYPVGKVLSEIQGRVVHSG 284

Query: 964  SINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNV 1065
             I    K  I     + DR LN+G DE +QLLN+
Sbjct: 285  EIEDADKAAICLSLMETDRCLNDGADEELQLLNI 318


>Q9GR07|RFC2|Q9GR07 (TrEMBL: Plasmodium falciparum) Replication factor
            C subunit 2.
          Length = 330

 Score =  245 bits (625), Expect = 8e-64
 Identities = 131/343 (38%), Positives = 211/343 (61%)
 Frame = +1

Query: 61   LHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKE 240
            + + PWVEKYRPK L+D+  Q + + +L + +++ N+PH++F+GPPGTGKTS I ALA E
Sbjct: 1    MENIPWVEKYRPKRLDDIVHQNNAVMMLKEVVRTKNMPHLIFHGPPGTGKTSAINALAHE 60

Query: 241  LYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDE 420
            L+G      RVLELNASD+RGI++VREKIK + R++IS            P +K+++LDE
Sbjct: 61   LFGKENISERVLELNASDDRGINVVREKIKAYTRISISKNKIHSETKEVLPSWKLVVLDE 120

Query: 421  ADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRL 600
            AD MT DAQSALRR +E Y+ +TRF+LICNYI +I DPI SRCS +RF+ +     + +L
Sbjct: 121  ADMMTEDAQSALRRIIEIYSNVTRFILICNYIHKISDPIFSRCSCYRFQSIPINIKKEKL 180

Query: 601  KYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITI 780
             YI Q EN+    +      ++++++ + GDLR+A++ LQ  + ++         + IT+
Sbjct: 181  LYICQNENIDIVDD-----ALEKIIETTEGDLRRAVSILQLCSCIN---------TKITL 226

Query: 781  QSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILD 960
             S+ + +G+  D+I+ ++I   K+K    +L++   Q II  G+    +    ++  + +
Sbjct: 227  NSVLDVSGLPSDNIVYKIIDACKMK--DLKLVEKTVQDIIEDGFDVAYIFKSFNNYFVTN 284

Query: 961  ESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
                  LK +I    F+ D +L+ G  ++IQLL+    +  +L
Sbjct: 285  TEYEDSLKYQILLELFRHDYRLHCGATQYIQLLSFASSVHSLL 327


>O96260|PFB0840W|O96260 (TrEMBL: Plasmodium falciparum) Replication
            factor C, 40 kDa subunit (Replication activator).
          Length = 330

 Score =  242 bits (617), Expect = 6e-63
 Identities = 130/343 (37%), Positives = 210/343 (61%)
 Frame = +1

Query: 61   LHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKE 240
            + + PWVEKYRPK L+D+  Q + + +L + +++ N+PH++F+GPPGTGKTS I ALA E
Sbjct: 1    MENIPWVEKYRPKRLDDIVHQNNAVMMLKEVVRTKNMPHLIFHGPPGTGKTSAINALAHE 60

Query: 241  LYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDE 420
            L+G      RVLELNASD+RGI++VREKIK + R++IS            P +K+++LDE
Sbjct: 61   LFGKENISERVLELNASDDRGINVVREKIKAYTRISISKNKIHSETKEVLPSWKLVVLDE 120

Query: 421  ADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRL 600
            AD MT DAQSALRR +E Y+ +TRF+LICNYI +I DPI SRCS +RF+ +     + +L
Sbjct: 121  ADMMTEDAQSALRRIIEIYSNVTRFILICNYIHKISDPIFSRCSCYRFQSIPINIKKEKL 180

Query: 601  KYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITI 780
             YI Q EN+    +      ++++++ + GDLR+A++ LQ  + ++         + IT+
Sbjct: 181  LYICQNENIDIVDD-----ALEKIIETTEGDLRRAVSILQLCSCIN---------TKITL 226

Query: 781  QSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILD 960
             S+ + +G+  D+I+ ++I   K+K    +L++   Q II  G+    +    ++  + +
Sbjct: 227  NSVLDVSGLPSDNIVYKIIDACKMK--DLKLVEKTVQDIIEDGFDVAYIFKSFNNYFVTN 284

Query: 961  ESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
                  LK +I     + D +L+ G  ++IQLL+    +  +L
Sbjct: 285  TEYEDSLKYQILLELSRHDYRLHCGATQYIQLLSFASSVHSLL 327


>Q9YBS7|APE1522|Q9YBS7 (TrEMBL: Aeropyrum pernix) 346AA long
            hypothetical replication factor C subunit.
          Length = 346

 Score =  227 bits (579), Expect = 2e-58
 Identities = 131/332 (39%), Positives = 202/332 (60%), Gaps = 5/332 (1%)
 Frame = +1

Query: 76   WVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGPN 255
            WVEKYRP+SL+D+  Q+H ++ L Q +K  N+PH+LF GPPGTGKT+   ALA +L+G N
Sbjct: 30   WVEKYRPRSLDDIVDQKHVVERLKQFVKQRNMPHLLFAGPPGTGKTTAAHALAHDLFGEN 89

Query: 256  LYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSMT 435
             Y+  +LELNASDERGI+++REK+K FAR           +  P  P+KI++LDEAD+MT
Sbjct: 90   -YRQYMLELNASDERGINVIREKVKEFARS----------RTPPEIPFKIVLLDEADNMT 138

Query: 436  NDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIGQ 615
            +DAQ ALRR ME Y+ +TRF+LI NY ++IIDPI SRC+ FRF+ L+ ++   RL+YI +
Sbjct: 139  SDAQQALRRLMELYSSVTRFILIANYPSKIIDPIQSRCAFFRFQPLSKQDVIERLRYIAE 198

Query: 616  QENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIRE 795
             E + +E E      +  + +IS GD+RKAI  LQ+A+ L +          +T+ ++  
Sbjct: 199  NEGVDYEEE-----ALDAIYEISEGDMRKAINVLQAASYLGK----------VTVDAVYR 243

Query: 796  TAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLI-----LD 960
              G+     + E++    LK   +     + + +I  G S + +  Q+H +L      + 
Sbjct: 244  VVGMAKPREVREMLA-TALKGDFTAARSLLRKIMIEYGMSGEDVARQIHRELFSTELKMP 302

Query: 961  ESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
            E +  L  + + ++ +    +L  G+D+ IQL
Sbjct: 303  EELRVLAADYLGEVHY----RLVEGSDDDIQL 330


>O28219|AF2060|O28219 (TrEMBL: Archaeoglobus fulgidus) Activator 1,
            replication factor C, 35 kDa subunit.
          Length = 319

 Score =  223 bits (569), Expect = 2e-57
 Identities = 139/335 (41%), Positives = 201/335 (60%)
 Frame = +1

Query: 76   WVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGPN 255
            WVEKYRP++L++V  Q+  I+ L   ++  N+PH+LF GPPGTGKT+T +ALA++L+G N
Sbjct: 7    WVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIALARDLFGEN 66

Query: 256  LYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSMT 435
             ++   +E+NASDERGI +VR KIK FAR                 P+KII LDEAD++T
Sbjct: 67   -WRDNFIEMNASDERGIDVVRHKIKEFARTAPIGGA----------PFKIIFLDEADALT 115

Query: 436  NDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIGQ 615
             DAQ+ALRRTME Y+   RF+L CNY++RII+PI SRC+ FRFK +  E  + RL  I +
Sbjct: 116  ADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICE 175

Query: 616  QENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIRE 795
            +E ++   +      ++ L+ ISGGD RKAI  LQ AA + E  D +      TI  I  
Sbjct: 176  KEGVKITEDG-----LEALIYISGGDFRKAINALQGAAAIGEVVDAD------TIYQITA 224

Query: 796  TAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESINS 975
            TA   P++ + ELIQ   LK       + +D+ ++  G S + ++ QL  + I+   I  
Sbjct: 225  TA--RPEE-MTELIQ-TALKGNFMEARELLDRLMVEYGMSGEDIVAQLF-REIISMPIKD 279

Query: 976  LLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQIS 1080
             LK ++     ++D +L  G +E IQL   L  +S
Sbjct: 280  SLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLS 314


>Q8ZYK4|PAE0734|Q8ZYK4 (TrEMBL: Pyrobaculum aerophilum) Replication
            factor C small subunit.
          Length = 329

 Score =  217 bits (553), Expect = 2e-55
 Identities = 130/339 (38%), Positives = 196/339 (57%), Gaps = 2/339 (0%)
 Frame = +1

Query: 76   WVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGPN 255
            W EKYRP+S ++V   E     L + +K+GN+PH+LFYGPPGTGKT+  L LA+ELYG  
Sbjct: 6    WFEKYRPRSFDEVVDLEEVKARLREFVKAGNMPHLLFYGPPGTGKTTMALVLARELYG-E 64

Query: 256  LYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSMT 435
             ++   LELNASDERGI+++RE++K FAR                 P+K++ILDEAD+MT
Sbjct: 65   YWRENTLELNASDERGINVIRERVKEFARTAPVGKA----------PFKLVILDEADNMT 114

Query: 436  NDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIGQ 615
            +DAQ ALRR ME YA  TRF+L+ NY++RIIDPI SRC+ FRF  +       RLK+I +
Sbjct: 115  SDAQQALRRIMEIYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMPRSLMAERLKFIAK 174

Query: 616  QENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIRE 795
             E +    +      I  + ++S GD+RKAI  LQ AA  ++  D N   ++ +      
Sbjct: 175  NEGVELRED-----AINMIYELSEGDMRKAINLLQVAAATNKVVDAN---AVASAAIAVR 226

Query: 796  TAGILPDDILAELIQFIKL--KTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESI 969
             A I+    LA    F+K   K ++   +K I  +  +  +  +++      ++ +D+ I
Sbjct: 227  PADIIELFNLAISGDFVKAREKLRELMYLKGIAGADFIRAFQRELI------RMPIDDDI 280

Query: 970  NSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQV 1086
                K +I+++   +D +L  G DE IQL  +L ++  +
Sbjct: 281  ----KAEIAELLADVDYRLTQGADEEIQLTYLLTKLGAI 315


>Q975D3|ST0475|Q975D3 (TrEMBL: Sulfolobus tokodaii) Putative
            replication factor C small subunit.
          Length = 327

 Score =  217 bits (552), Expect = 2e-55
 Identities = 125/345 (36%), Positives = 204/345 (59%), Gaps = 1/345 (0%)
 Frame = +1

Query: 49   EEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILA 228
            EEE L    W EKYRP+SL+D+ +Q+  ++ L + +K  N+PH+LF GPPGTGKT+  LA
Sbjct: 4    EEEIL----WAEKYRPRSLDDIVNQKDIVERLKRFVKDKNMPHLLFSGPPGTGKTTAALA 59

Query: 229  LAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKII 408
            L  +LYG N Y+   LELNASDERGI ++R K+K FAR                 P+K++
Sbjct: 60   LVHDLYGDN-YRQYFLELNASDERGIDVIRNKVKEFARTVAGGNV----------PFKVV 108

Query: 409  ILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENA 588
            +LDEAD+MT DAQ ALRRTME Y   TRF+L CNY+++II+PI SR + FRF  L  E+ 
Sbjct: 109  LLDEADNMTADAQQALRRTMELYTETTRFILACNYLSKIIEPIQSRTALFRFYPLKKEDV 168

Query: 589  QLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQS 768
              RL YI + E + +     + + ++ +  I+ GD+RKAI  LQ+++   +         
Sbjct: 169  VARLAYIAKNEKVEY-----DQKALETIYDITQGDMRKAINILQASSVYGK--------- 214

Query: 769  LITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDK 948
             +T++++ +  G+     + E+I  + L+    +  + + + ++  G S + ++ Q+H +
Sbjct: 215  -VTVEAVYKVLGLAQPKEIREMI-MLALQGNFLKAREKLRELLVNYGLSGEDIIKQIHRE 272

Query: 949  LILDE-SINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQIS 1080
            +  +E +I   LK  +     +++ ++  G D+ IQL  +L +++
Sbjct: 273  VTGNEINIPDDLKVLLVDYIGEVEYRIMEGADDEIQLNALLAKLA 317


>Q8PVY4|MM1821|Q8PVY4 (TrEMBL: Methanosarcina mazei (Methanosarcina
            frisia)) Replication factor C subunit.
          Length = 338

 Score =  213 bits (543), Expect = 2e-54
 Identities = 130/343 (37%), Positives = 203/343 (59%), Gaps = 7/343 (2%)
 Frame = +1

Query: 49   EEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILA 228
            E+ K+    W+EKYRP  LN V+ QE TI+ L   + + NLPH+LF GPPG GKT++ ++
Sbjct: 6    EDFKIKEEIWIEKYRPVRLNQVAGQEETIERLMSYVATKNLPHLLFSGPPGVGKTASAVS 65

Query: 229  LAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKII 408
            +A+E++G +L++    ELNASDERGI IVR KIKNFA+                 P+KII
Sbjct: 66   IAREIFGEDLWRENFTELNASDERGIDIVRNKIKNFAKTAPMGGA----------PFKII 115

Query: 409  ILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENA 588
             LDEAD++T+DAQSALRRTME ++   RF+L CNY ++II+PI SRC+ +RF+ L+++  
Sbjct: 116  FLDEADALTSDAQSALRRTMEKFSSNCRFILSCNYSSKIIEPIQSRCAVYRFRRLSDKAI 175

Query: 589  QLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQS 768
            + RL+YI ++++L       E      L+ ++ GD+RKA+  LQ+AA +    D+    S
Sbjct: 176  RERLEYIAKEQDLSITDGGYE-----ALIYVAQGDMRKAVNSLQAAAFI----DVEKPIS 226

Query: 769  LITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLH-- 942
              TI   R TA   P++I   +   ++   + +R  K +++ +   G S + ++ Q++  
Sbjct: 227  RETI--YRTTATANPEEIKNLIETALRGNFRVAR--KELNRLLYEEGLSGEDIVGQIYRV 282

Query: 943  -----DKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
                 + +ILD  ++      +  I  + D +L  G  E IQL
Sbjct: 283  VSEMDNLMILDLGLSERDIVGLVDIIGETDFRLTEGASEKIQL 325


>Q9UXF5|RFC|Q9UXF5 (TrEMBL: Sulfolobus solfataricus) Activator 1,
            replication factor C, small subunit (RFC).
          Length = 330

 Score =  211 bits (538), Expect = 9e-54
 Identities = 124/342 (36%), Positives = 197/342 (57%), Gaps = 1/342 (0%)
 Frame = +1

Query: 58   KLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAK 237
            K+    W EKYRPK+L+D+ +Q   I  L + +K  N+PH+LF GPPGTGKT+  LAL  
Sbjct: 4    KVEEILWAEKYRPKTLDDIVNQREIIDRLKKFVKEKNMPHLLFAGPPGTGKTTAALALVH 63

Query: 238  ELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILD 417
            +LYG N Y    LELNASDERGI ++R K+K FAR  I              P+K+++LD
Sbjct: 64   DLYGDN-YTEYFLELNASDERGIDVIRNKVKEFARTVIPGDI----------PFKVVLLD 112

Query: 418  EADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLR 597
            EAD+MT DAQ ALRRTME Y   TRF+L CNY+++II+PI SR + FRF  L  E+   R
Sbjct: 113  EADNMTADAQQALRRTMELYTENTRFILACNYLSKIIEPIQSRTALFRFYPLKKEDVVNR 172

Query: 598  LKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLIT 777
            L YI + E   +     + + ++ +  I+ GD+RK+I  LQ+A+   +          I+
Sbjct: 173  LIYIAKNEKAEY-----DQKALETIYDITMGDMRKSINILQAASAYGK----------IS 217

Query: 778  IQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLIL 957
            ++++ +  G+     + E+I  + L+ + ++    +   +I  G S + ++ Q+H ++  
Sbjct: 218  VEAVFKVLGLAQPKEVREMIN-LALQGKFTQARDKLRTLLITYGLSGEDIVKQIHREITS 276

Query: 958  DE-SINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQIS 1080
             E  I+  L+  +     + + ++  G D+ IQL  +L +++
Sbjct: 277  SEIQISEELRVLLLDYIGETEFRIIEGADDEIQLSALLAKMA 318


>P53016|F31E3.3|RFC4_CAEEL (SP: Caenorhabditis elegans) Putative
            activator 1 37 kDa subunit (Replication factor C 37 kDa
            subunit) (A1 37 kDa subunit) (RF-C 37 kDa subunit)
            (RFC37).
          Length = 334

 Score =  210 bits (534), Expect = 3e-53
 Identities = 122/339 (35%), Positives = 201/339 (59%), Gaps = 1/339 (0%)
 Frame = +1

Query: 76   WVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGPN 255
            W EKYRPK+L+D++ Q+  + +L   ++  +LPH+LFYGPPGTGKTS  LA  ++L+  N
Sbjct: 17   WTEKYRPKTLDDIAYQDEVVTMLKGALQGRDLPHLLFYGPPGTGKTSAALAFCRQLFPKN 76

Query: 256  LYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSMT 435
            ++  RVL+LNASDERGI++VR+KI++F++ ++ +  +ED+        KIIILDE D+MT
Sbjct: 77   IFHDRVLDLNASDERGIAVVRQKIQSFSKSSLGHSHREDVLK-----LKIIILDEVDAMT 131

Query: 436  NDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIGQ 615
             +AQ+A+RR +E+++  TRF+LICNY++R+I P+ SRC+KFRFK L  E    RL+ I  
Sbjct: 132  REAQAAMRRVIEDFSKTTRFILICNYVSRLIPPVVSRCAKFRFKSLPAEIQVQRLRTICD 191

Query: 616  QENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIRE 795
             E      +      ++++++ S GDLR+A+  LQS A + ++ D N     +   S   
Sbjct: 192  AEGTPMSDDE-----LKQVMEYSEGDLRRAVCTLQSLAPILKSGDDNARNCYLRGSSDSL 246

Query: 796  TAGILPDDIL-AELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESIN 972
                +   IL A++ Q I        L K I +S     +  +     + + +I DE+I 
Sbjct: 247  LISNVCKSILTADVPQII-------ALTKDITKSCTGVAFIRRCFQQLMDEDVINDENIG 299

Query: 973  SLLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
             +      ++    ++++ +G D    LL+ LL + + +
Sbjct: 300  VM-----GKLVATCEKRILDGCDLENNLLDFLLTLRETI 333


>Q8TSX5|RFCS|Q8TSX5 (TrEMBL: Methanosarcina acetivorans) Replication
            factor C, small subunit.
          Length = 338

 Score =  209 bits (532), Expect = 5e-53
 Identities = 126/343 (36%), Positives = 197/343 (57%), Gaps = 7/343 (2%)
 Frame = +1

Query: 49   EEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILA 228
            E+ K+    W+EKYRP  LN V+ Q+ TI+ L   + + NLPH+LF GPPG GKT++ ++
Sbjct: 6    EDSKIKEEIWIEKYRPVRLNQVAGQDETIERLKSYVATKNLPHLLFSGPPGVGKTASAVS 65

Query: 229  LAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKII 408
            +A+E++G +L++    ELNASDERGI IVR KIKNFA+                 P+KII
Sbjct: 66   IAREIFGEDLWRENFTELNASDERGIDIVRNKIKNFAKTAPIGGA----------PFKII 115

Query: 409  ILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENA 588
             LDEAD++T DAQSALRRTME ++   RF+L CNY ++II+PI SRC+ +RF+ L++E  
Sbjct: 116  FLDEADALTADAQSALRRTMERFSSNCRFILSCNYSSKIIEPIQSRCAVYRFRRLSDEAI 175

Query: 589  QLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQS 768
            + RL+YI   + L       E      L+ ++ GD+RKA+  LQ+AA       I+  +S
Sbjct: 176  KERLEYIAGDQGLSITEGGYE-----ALIYVAQGDMRKAVNSLQAAA------FIDTDKS 224

Query: 769  LITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLH-- 942
            +      R TA   P++I   +   ++   + +R  K +++ +   G S + ++ Q++  
Sbjct: 225  ISRETIYRTTATANPEEIKNLIETALRGNFRIAR--KELNRLLYEEGLSGEDIVGQIYRV 282

Query: 943  -----DKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
                 + ++LD  +       +  +  + D +L  G  E IQL
Sbjct: 283  VSEMDNLMVLDLGLTERDIVALVDVIGETDFRLTEGASEKIQL 325


>Q9VKW3|RFC3|Q9VKW3 (TrEMBL: Drosophila melanogaster (Fruit fly))
           CG5313 protein (Replication factor C subunit 3)
           (SD11293p).
          Length = 332

 Score =  207 bits (528), Expect = 1e-52
 Identities = 121/298 (40%), Positives = 170/298 (57%), Gaps = 27/298 (9%)
 Frame = +1

Query: 73  PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
           PWVEKYRP  L+D+ S E  I  +T+ I    LPH+LFYGPPGTGKTSTILA A++LY P
Sbjct: 12  PWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGKTSTILACARQLYSP 71

Query: 253 NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
             +KS VLELNASD+RGI IVR +I NFA            +   C  +K+IILDEAD+M
Sbjct: 72  QQFKSMVLELNASDDRGIGIVRGQILNFA----------STRTIFCDTFKLIILDEADAM 121

Query: 433 TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
           TNDAQ+ALRR +E Y    RF +ICNY+++II  + SRC++FRF  L+ +    RL+ I 
Sbjct: 122 TNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKII 181

Query: 613 QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINH----------- 759
           + E ++   +       + LL ++ GD+RK +  LQS     +T + ++           
Sbjct: 182 EAEAVQITEDGK-----RALLTLAKGDMRKVLNVLQSTVMAFDTVNEDNVYMCVGYPLRQ 236

Query: 760 ---------------HQSLITIQSIRETAGILPDDILAELIQFI-KLKTQQSRLIKYI 885
                            S  T++S +   G+  +DI+ EL  F+ +L+   S + K I
Sbjct: 237 DIEQILKALLSGSSLEDSFKTVESAKYARGLALEDIITELHLFVMRLELPMSVMNKLI 294


>Q8ZWS2|PAE1646|Q8ZWS2 (TrEMBL: Pyrobaculum aerophilum) Replication
            factor C small subunit.
          Length = 319

 Score =  200 bits (509), Expect = 2e-50
 Identities = 120/338 (35%), Positives = 188/338 (55%)
 Frame = +1

Query: 76   WVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGPN 255
            W EKYRP+S ++V   E     L Q +K+GN+PH+LFYGPPGTGKT+  L LA+ELYG  
Sbjct: 6    WFEKYRPRSFDEVVDLEEVKARLRQFVKAGNMPHLLFYGPPGTGKTTMALVLARELYG-E 64

Query: 256  LYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSMT 435
             ++   LELNASDERGI+++RE++K FAR                 P+K++ILDEAD+MT
Sbjct: 65   YWRENTLELNASDERGINVIRERVKEFARTAPVGKA----------PFKLVILDEADNMT 114

Query: 436  NDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIGQ 615
            +DAQ ALRR ME YA  TRF+L+ NY++ II+PI SR    RF  L  E    RL+YI +
Sbjct: 115  SDAQQALRRIMEIYAQNTRFILLANYVSGIIEPIQSRTVMIRFSPLPKEAVFARLRYIAE 174

Query: 616  QENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIRE 795
             E ++   +      ++ + + + GD+R+AI  LQ AA +S+          +T + + +
Sbjct: 175  NEGVKVSDD-----ALEAIYEFTQGDMRRAINALQIAATVSKA---------VTEEVVAK 220

Query: 796  TAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLILDESINS 975
              G++   +L E + +  +K    +    I   +   G     ++ Q+H ++ L   +  
Sbjct: 221  ALGMVSPRLLRETL-YEAVKGSFGKAATQIYGFVADGGVGELEIIKQIHREM-LRLDVQE 278

Query: 976  LLKNKISQIFFQLDRKLNNGTDEHIQLLNVLLQISQVL 1089
             +K +I+ I  +    +  G     Q+   L ++ ++L
Sbjct: 279  YVKPEIAYIIAEAHYAILRGAHGLTQIYGALAKVRRLL 316


>P34429|F44B9.8|RFC5_CAEEL (SP: Caenorhabditis elegans) Putative
            activator 1 36 kDa subunit (Replication factor C 36 kDa
            subunit) (A1 36 kDa subunit) (RF-C 36 kDa subunit)
            (Replication factor C subunit 5).
          Length = 388

 Score =  199 bits (506), Expect = 5e-50
 Identities = 125/356 (35%), Positives = 190/356 (53%), Gaps = 24/356 (6%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRP  L+++ + E  +K LT+ I++  LPH+LFYGPPGTGKT+T+LA A+++Y P
Sbjct: 30   PWVEKYRPSKLDELVAHEQIVKTLTKFIENRTLPHLLFYGPPGTGKTTTVLAAARQMYSP 89

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
                S VLELNASDERGI +VR  I NFA+ T          N    P+K++ILDEAD+M
Sbjct: 90   TKMASMVLELNASDERGIDVVRNTIVNFAQ-TKGLQAFSTSSNTGTVPFKLVILDEADAM 148

Query: 433  TNDAQSALR--------------------RTMENYAGITRFVLICNYITRIIDPITSRCS 552
            T DAQ+ALR                    R +E Y    RF +ICNY+  I+  I SRC+
Sbjct: 149  TKDAQNALRRLDKTDYEQNIIIHNVNIYFRVIEKYTDNVRFCIICNYLASIVPAIQSRCT 208

Query: 553  KFRFKLLNNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAK 732
            +FRF  L+ +    RL+YI + E L+   +  +      LL +S GD+R  I  LQS A 
Sbjct: 209  RFRFAPLDQKLIVPRLEYIVETEQLKMTPDGKD-----ALLIVSKGDMRTVINTLQSTAM 263

Query: 733  LSETFDINHHQSLITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGW 912
              +T   N         ++ +  G      + E+++ + L     + +  I   +  +G+
Sbjct: 264  SFDTVSEN---------TVYQCIGQPTPKEMKEVVKTL-LNDPSKKCMNTIQTKLFENGY 313

Query: 913  SAQILLDQLHDKL----ILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVL 1068
            + Q ++  LHD +    I DE++++++         +++  L+ G     QL  V+
Sbjct: 314  ALQDVITHLHDFVFTLDIPDEAMSAIITG-----LGEVEENLSTGCSNETQLAAVV 364


>Q8IKK4|PF14_0601|Q8IKK4 (TrEMBL: Plasmodium falciparum (isolate 3D7))
            Replication factor C3.
          Length = 344

 Score =  198 bits (503), Expect = 1e-49
 Identities = 127/334 (38%), Positives = 184/334 (55%), Gaps = 5/334 (1%)
 Frame = +1

Query: 70   TPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYG 249
            TPWVEKYRP  LND+ S E  I  + + ++ G LPH+L +GPPGTGKTSTILA+ KELYG
Sbjct: 13   TPWVEKYRPNVLNDIISHEQVISTIKRFVQKGELPHLLLHGPPGTGKTSTILAVCKELYG 72

Query: 250  PNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADS 429
             +   S VLELNASD+RGI+++R++IK FA       +K           K+IILDEAD 
Sbjct: 73   -DKRSSFVLELNASDDRGINVIRDQIKTFAE------SKNHYTTCEKTTLKLIILDEADH 125

Query: 430  MTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYI 609
            MT  AQ+A+RR MENYA   RF L+CNY+ +I   I SRC+ FRF  L  E  + +   I
Sbjct: 126  MTYPAQNAMRRIMENYAKNVRFCLLCNYVNKITPAIQSRCTAFRFAPLKKEYMKNKALDI 185

Query: 610  GQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSI 789
             + EN+     N     I  L+++  GD+R+ +  LQ          ++H   +I    I
Sbjct: 186  AKSENV-----NLTEGGIDSLIRVGHGDMRRILNCLQ-------VVSLSHKNLVIDENVI 233

Query: 790  RETAGI-LPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLIL--- 957
              T  I LP +    L  F K   ++S   +++       G+S + ++  L++ ++    
Sbjct: 234  LSTLDIPLPSETKKILEYFTKGSIKES--YEFVSNLQYDKGYSTKDIMMCLYESVLTYDF 291

Query: 958  -DESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
             D +   LLKN     F +++ + ++G  E I L
Sbjct: 292  PDSAFCLLLKN-----FGEIEERCSSGASEQITL 320


>Q9GR09|RFC3|Q9GR09 (TrEMBL: Plasmodium falciparum) Replication factor
            C3.
          Length = 344

 Score =  198 bits (503), Expect = 1e-49
 Identities = 127/334 (38%), Positives = 184/334 (55%), Gaps = 5/334 (1%)
 Frame = +1

Query: 70   TPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYG 249
            TPWVEKYRP  LND+ S E  I  + + ++ G LPH+L +GPPGTGKTSTILA+ KELYG
Sbjct: 13   TPWVEKYRPNVLNDIISHEQVISTIKRFVQKGELPHLLLHGPPGTGKTSTILAVCKELYG 72

Query: 250  PNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADS 429
             +   S VLELNASD+RGI+++R++IK FA       +K           K+IILDEAD 
Sbjct: 73   -DKRSSFVLELNASDDRGINVIRDQIKTFAE------SKNHYTTCEKTTLKLIILDEADH 125

Query: 430  MTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYI 609
            MT  AQ+A+RR MENYA   RF L+CNY+ +I   I SRC+ FRF  L  E  + +   I
Sbjct: 126  MTYPAQNAMRRIMENYAKNVRFCLLCNYVNKITPAIQSRCTAFRFAPLKKEYMKNKALDI 185

Query: 610  GQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSI 789
             + EN+     N     I  L+++  GD+R+ +  LQ          ++H   +I    I
Sbjct: 186  AKSENV-----NLTEGGIDSLIRVGHGDMRRILNCLQ-------VVSLSHKNLVIDENVI 233

Query: 790  RETAGI-LPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLHDKLIL--- 957
              T  I LP +    L  F K   ++S   +++       G+S + ++  L++ ++    
Sbjct: 234  LSTLDIPLPSETKKILEYFTKGSIKES--YEFVSNLQYDKGYSTKDIMMCLYESVLTYDF 291

Query: 958  -DESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
             D +   LLKN     F +++ + ++G  E I L
Sbjct: 292  PDSAFCLLLKN-----FGEIEERCSSGASEQITL 320


>O26343|MTH241|O26343 (TrEMBL: Methanobacterium thermoautotrophicum)
            Replication factor C, small subunit.
          Length = 321

 Score =  197 bits (501), Expect = 2e-49
 Identities = 123/332 (37%), Positives = 182/332 (54%), Gaps = 4/332 (1%)
 Frame = +1

Query: 73   PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
            PWVEKYRP+ L+D+  QEH I  L + ++  ++P+++F GP G GKT+  LALA+E+ G 
Sbjct: 7    PWVEKYRPQKLDDIVGQEHIIPRLKRYVEEKSMPNLMFTGPAGVGKTTAALALAREILG- 65

Query: 253  NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
              ++   LELNASD RGI  VR  IKNF RL                P++II LDE D+M
Sbjct: 66   EYWRQNFLELNASDARGIDTVRTSIKNFCRLKPVGA-----------PFRIIFLDEVDNM 114

Query: 433  TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
            T DAQ ALRR ME Y   + F+L CNY ++IIDPI SRC+ FRF  L       RL+YI 
Sbjct: 115  TKDAQHALRREMEMYTKTSSFILSCNYSSKIIDPIQSRCAIFRFLPLKGHQIIKRLEYIA 174

Query: 613  QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDINHHQSLITIQSIR 792
            ++ENL +E+       ++ ++  + GDLRKAI  LQSAA L E          IT  SI 
Sbjct: 175  EKENLEYEA-----HALETIVYFAEGDLRKAINLLQSAASLGEK---------ITESSIY 220

Query: 793  ETAG-ILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWSAQILLDQLH---DKLILD 960
            +      P D+   +   +  K  ++R    + + ++L G S + ++ Q++    +L ++
Sbjct: 221  DVVSRARPKDVRKMIKTILDGKFMEAR--DMLREIMVLQGISGEDMVTQIYQELSRLAME 278

Query: 961  ESINSLLKNKISQIFFQLDRKLNNGTDEHIQL 1056
              ++      +     + D ++  G +  IQL
Sbjct: 279  GEVDGDRYVGLIDAIGEYDFRIREGANPRIQL 310


>P40937|RFC5|RFC5_HUMAN (SP: Homo sapiens (Human)) Activator 1 36 kDa
            subunit (Replication factor C 36 kDa subunit) (A1 36 kDa
            subunit) (RF-C 36 kDa subunit) (RFC36) (Replication
            factor C subunit 5).
          Length = 340

 Score =  197 bits (501), Expect = 2e-49
 Identities = 126/354 (35%), Positives = 200/354 (56%), Gaps = 3/354 (0%)
 Frame = +1

Query: 16   TTIRKQKNQAYEEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGP 195
            T+  KQ+ Q     K+ + PWVEKYRP++LND+ S +  +  + + I    LPH+L YGP
Sbjct: 3    TSALKQQEQP-AATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGP 61

Query: 196  PGTGKTSTILALAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDL 375
            PGTGKTSTILA AK+LY    + S VLELNASD+RGI I+R  I +FA       T+   
Sbjct: 62   PGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFA------STRTIF 115

Query: 376  QNYPCPPYKIIILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSK 555
            +      +K++ILDEAD+MT DAQ+ALRR +E +   TRF LICNY+++II  + SRC++
Sbjct: 116  KK----GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTR 171

Query: 556  FRFKLLNNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKL 735
            FRF  L  E    RL+++ ++E +    +      ++ L+ +S GD+R+A+  LQS    
Sbjct: 172  FRFGPLTPELMVPRLEHVVEEEKVDISEDG-----MKALVTLSSGDMRRALNILQST--- 223

Query: 736  SETFDINHHQSLITIQSIRETAGILPDDILAELIQFIKLKTQQSRLIKYIDQSIILSGWS 915
                  N     +T +++    G      +A ++ ++ L    +   + I +   L G +
Sbjct: 224  ------NMAFGKVTEETVYTCTGHPLKSDIANILDWM-LNQDFTTAYRNITELKTLKGLA 276

Query: 916  AQILLDQLH---DKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHIQLLNVL 1068
               +L ++H    ++    S+   L  K++ I    + +L+ GT+E IQL +++
Sbjct: 277  LHDILTEIHLFVHRVDFPSSVRIHLLTKMADI----EYRLSVGTNEKIQLSSLI 326


>Q872Q7|B13B3.180|Q872Q7 (TrEMBL: Neurospora crassa) Related to
            replication factor C chain Rfc3.
          Length = 389

 Score =  196 bits (497), Expect = 5e-49
 Identities = 117/361 (32%), Positives = 198/361 (54%), Gaps = 12/361 (3%)
 Frame = +1

Query: 7    STGTTIRKQKNQAYEEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLF 186
            +T T   K+       E     PWVEKYRP SL+DVS Q+  +  + + + +  LPH+LF
Sbjct: 22   ATNTAKGKRSAANLPVEAEDSLPWVEKYRPVSLSDVSGQQDILATINKFVDTNRLPHLLF 81

Query: 187  YGPPGTGKTSTILALAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTK 366
            YGPPGTGKTST+LALA+++YG    +  VLELNASD+RGI +VRE+IK FA         
Sbjct: 82   YGPPGTGKTSTVLALARQIYGAANMRQMVLELNASDDRGIDVVREQIKTFASTKQIFSLG 141

Query: 367  EDLQNYPCPPYKIIILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSR 546
                      +K+IILDEAD+MT+ AQ ALRR ME Y   TRF +I NY  ++   + SR
Sbjct: 142  SSSSRSGLAGFKLIILDEADAMTSTAQMALRRIMEKYTANTRFCIIANYSHKLSPALLSR 201

Query: 547  CSKFRFKLLNNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQ-- 720
            C++FRF  L  ++ ++ +  +  +EN++   +  +      L+++S GD+R+A+  LQ  
Sbjct: 202  CTRFRFSPLKEKDIRVLVDKVIDEENVKILPDATD-----ALVRLSKGDMRRALNVLQAC 256

Query: 721  ----------SAAKLSETFDINHHQSLITIQSIRETAGILPDDILAELIQFIKLKTQQSR 870
                      +A K++E   +   +  ITI++I +     P D + +++  +   +  + 
Sbjct: 257  HASSTPLQPKNAPKIAEKDIV---RETITIRTIYDCVAAPPPDAIKKILSTLLSTSDVTT 313

Query: 871  LIKYIDQSIILSGWSAQILLDQLHDKLILDESINSLLKNKISQIFFQLDRKLNNGTDEHI 1050
             +  I+   +  G +   ++  L ++++  E    ++   + ++  +++ ++ +G  E I
Sbjct: 314  CLSTINTLKVAQGLALADIITALSEEIVKLEVKPQVMITWLDEL-AKIEHRVASGAGEVI 372

Query: 1051 Q 1053
            Q
Sbjct: 373  Q 373


>O14003|RFC3|RFC3_SCHPO (SP: Schizosaccharomyces pombe (Fission
           yeast)) Activator 1 subunit 3 (Replication factor C
           subunit 3) (Replication factor C3).
          Length = 342

 Score =  196 bits (497), Expect = 5e-49
 Identities = 119/299 (39%), Positives = 172/299 (57%), Gaps = 26/299 (8%)
 Frame = +1

Query: 73  PWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTGKTSTILALAKELYGP 252
           PWVEKYRP +L DV S +  I  L + I S  +PHMLFYGPPGTGKTSTILA A+++YGP
Sbjct: 24  PWVEKYRPANLEDVVSHKDIISTLEKFISSNRVPHMLFYGPPGTGKTSTILACARKIYGP 83

Query: 253 NLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYPCPPYKIIILDEADSM 432
           N Y+++++ELNASD+RGI  VRE+IKNFA            +      +K+IILDEAD+M
Sbjct: 84  N-YRNQLMELNASDDRGIDAVREQIKNFA----------STRQIFASTFKMIILDEADAM 132

Query: 433 TNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFKLLNNENAQLRLKYIG 612
           T  AQ+ALRR +E Y    RF +ICNYI +I   I SRC++FRF+ L  +  +  + ++ 
Sbjct: 133 TLAAQNALRRVIEKYTKNVRFCIICNYINKISPAIQSRCTRFRFQPLPPKEIEKTVDHVI 192

Query: 613 QQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSAAKLSETFDI--------NHHQS 768
           Q E+   + +         +L++S GD+RKA+  LQ+     +  D+        + H S
Sbjct: 193 QSEHCNIDPDAK-----MAVLRLSKGDMRKALNILQACHAAYDHIDVSAIYNCVGHPHPS 247

Query: 769 LI-----------------TIQSIRETAGILPDDILAELIQFI-KLKTQQSRLIKYIDQ 891
            I                 TI SI++  G+   DIL  + + + +L+ + +  I  +DQ
Sbjct: 248 DIDYFLKSIMNDEFVIAFNTISSIKQQKGLALQDILTCIFEALDELEIKPNAKIFILDQ 306


>O74111|RFC3|RFC3_ARXAD (SP: Arxula adeninivorans (Yeast)) Activator
           1 subunit 3 (Replication factor C subunit 3)
           (Replication factor C3).
          Length = 338

 Score =  195 bits (496), Expect = 7e-49
 Identities = 115/316 (36%), Positives = 179/316 (56%), Gaps = 29/316 (9%)
 Frame = +1

Query: 28  KQKNQAYEEEKLHHTPWVEKYRPKSLNDVSSQEHTIKVLTQTIKSGNLPHMLFYGPPGTG 207
           K K     E++ +  PWVEKYRP +L++V+  E  I  + + ++ G LPH+LF+GPPGTG
Sbjct: 3   KGKKVETVEKQENSLPWVEKYRPTTLDEVAGHEGVITTIKKFVEEGKLPHLLFHGPPGTG 62

Query: 208 KTSTILALAKELYGPNLYKSRVLELNASDERGISIVREKIKNFARLTISNPTKEDLQNYP 387
           KT+TI+A+A+++YG N Y++ +LELNASDERGI +VR++IK FA       T++   +  
Sbjct: 63  KTTTIIAVARQIYGKN-YRNMILELNASDERGIDVVRDQIKTFA------STRQIFSS-- 113

Query: 388 CPPYKIIILDEADSMTNDAQSALRRTMENYAGITRFVLICNYITRIIDPITSRCSKFRFK 567
              +K++ILDEAD+MTN AQ+ALRR +E Y+  TRF ++ NY  ++   + SRC++FRF 
Sbjct: 114 --GFKLVILDEADAMTNAAQNALRRIIEKYSAHTRFCILANYTHKLNPALLSRCTRFRFS 171

Query: 568 LLNNENAQLRLKYIGQQENLRFESENNEHQVIQELLKISGGDLRKAITYLQSA------- 726
            L  +  + RL ++ +QE++    E       Q LL +S GD+R+A+  LQ+        
Sbjct: 172 PLKEDAIKHRLAHVIEQESVDLSPE-----AFQSLLHLSSGDMRRALNVLQACYASVDAG 226

Query: 727 ---------------------AKLSETFDINHHQSLITIQSIRETAGI-LPDDILAELIQ 840
                                  L    D +   +L T   I+++ G+ L D + A  ++
Sbjct: 227 EQISEELVYDCVGSPRPADIRTVLQAVLDGSWESALHTFSYIKQSKGLALADMLTAFAVE 286

Query: 841 FIKLKTQQSRLIKYID 888
           F KL  Q    I  +D
Sbjct: 287 FQKLDLQNKTRIALLD 302


  Database: sptrembl
    Posted date:  Oct 14, 2003  6:47 PM
  Number of letters in database: 339,323,595
  Number of sequences in database:  1,070,300
  
Lambda     K      H
   0.317    0.135    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 266,689,506
Number of Sequences: 1070300
Number of extensions: 4991932
Number of successful extensions: 27644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25641
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27083
length of database: 339,323,595
effective HSP length: 123
effective length of database: 207,676,695
effective search space used: 49634730105
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)