BLASTX 2.2.6 [Apr-09-2003]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Candida_albicans_chr7-r1-707318-705636-9
         (1680 letters)

Database: sptrembl 
           1,070,300 sequences; 339,323,595 total letters

Searching.................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Q9C1Z8|PDI|Q9C1Z8 (TrEMBL: Pichia pastoris (Yeast)) Protein disu...   397   e-109
Q9Y8F3|PDI1|Q9Y8F3 (TrEMBL: Kluyveromyces marxianus (Yeast) (Klu...   389   e-107
Q9URT0|PDI1|Q9URT0 (TrEMBL: Kluyveromyces lactis (Yeast)) Protei...   377   e-103
P17967|PDI1|PDI_YEAST (SP: Saccharomyces cerevisiae (Baker's yea...   357   3e-97
O74568|PDI1|O74568 (TrEMBL: Trichoderma reesei (Hypocrea jecorin...   346   4e-94
Q00248|PDIA|PDI_ASPOR (SP: Aspergillus oryzae) Protein disulfide...   341   1e-92
P55059||PDI_HUMIN (SP: Humicola insolens) Protein disulfide isom...   332   1e-89
Q12730|PDIA|PDI_ASPNG (SP: Aspergillus niger) Protein disulfide ...   328   2e-88
Q10057|SPAC1F5.02|PDI1_SCHPO (SP: Schizosaccharomyces pombe (Fis...   285   2e-75
P32474|EUG1|EUG1_YEAST (SP: Saccharomyces cerevisiae (Baker's ye...   281   1e-74
Q96VF3||Q96VF3 (TrEMBL: Ustilago maydis (Smut fungus)) Hypotheti...   276   5e-73
Q91Z81||Q91Z81 (TrEMBL: Cricetulus griseus (Chinese hamster)) ER...   231   2e-59
Q8JG64|GRP58|Q8JG64 (TrEMBL: Gallus gallus (Chicken)) Glucose re...   231   2e-59
Q99LF6|GRP58|Q99LF6 (TrEMBL: Mus musculus (Mouse)) Similar to ER...   231   2e-59
Q8C2F4|GRP58|Q8C2F4 (TrEMBL: Mus musculus (Mouse)) Glucose regul...   231   2e-59
Q26593||Q26593 (TrEMBL: Schistosoma mansoni (Blood fluke)) Prote...   228   1e-58
O17908|H06O01.1|O17908 (TrEMBL: Caenorhabditis elegans) H06O01.1...   228   1e-58
P27773|GRP58|PDA3_MOUSE (SP: Mus musculus (Mouse)) Protein disul...   228   2e-58
Q9V630|ERP60|Q9V630 (TrEMBL: Drosophila melanogaster (Fruit fly)...   225   1e-57
P11598|GRP58|PDA3_RAT (SP: Rattus norvegicus (Rat)) Protein disu...   224   2e-57
Q7ZWU3||Q7ZWU3 (TrEMBL: Xenopus laevis (African clawed frog)) Hy...   223   4e-57
Q8IYF8||Q8IYF8 (TrEMBL: Homo sapiens (Human)) Hypothetical prote...   223   5e-57
P30101|GRP58|PDA3_HUMAN (SP: Homo sapiens (Human)) Protein disul...   223   5e-57
Q9TWZ1|PDI|Q9TWZ1 (TrEMBL: Drosophila melanogaster (Fruit fly)) ...   221   2e-56
P38657|GRP58|PDA3_BOVIN (SP: Bos taurus (Bovine)) Protein disulf...   221   2e-56
Q9FE55|PDI|Q9FE55 (TrEMBL: Triticum aestivum (Wheat)) Protein di...   219   8e-56
O76191|NDITG|O76191 (TrEMBL: Dirofilaria immitis (Canine heartwo...   218   1e-55
Q93XQ7|PDI3|Q93XQ7 (TrEMBL: Triticum aestivum (Wheat)) Protein d...   218   2e-55
Q93XQ8|PDI2|Q93XQ8 (TrEMBL: Triticum aestivum (Wheat)) Protein d...   217   3e-55
P52589|PDI|PDI_WHEAT (SP: Triticum aestivum (Wheat)) Protein dis...   217   3e-55

>Q9C1Z8|PDI|Q9C1Z8 (TrEMBL: Pichia pastoris (Yeast)) Protein
            disulphide isomerase.
          Length = 517

 Score =  397 bits (1020), Expect = e-109
 Identities = 217/531 (40%), Positives = 326/531 (61%), Gaps = 6/531 (1%)
 Frame = +1

Query: 10   WTYSTKVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFA 189
            + +  K +A++L+ +++  AS   D +A+A  +S VVKLT   F SFI  NP +LAEFFA
Sbjct: 3    FNWDIKTVASILSALTLAQAS---DQEAIAPEDSHVVKLTEATFESFITSNPHVLAEFFA 59

Query: 190  PWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDS 369
            PWCG+CK LGPE   AA+ L ++  ++K+AQIDCTE++ LC  + I+GYPTLK+   G+ 
Sbjct: 60   PWCGHCKKLGPELVSAAEILKDNE-QVKIAQIDCTEEKELCQGYEIKGYPTLKVFH-GEV 117

Query: 370  KTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTE----D 537
            +   DYQG R++  I  YM+KQSLP V      ++LD  I    +P ++Q+ P +    +
Sbjct: 118  EVPSDYQGQRQSQSIVSYMLKQSLPPVSEINATKDLDDTIAEAKEPVIVQVLPEDASNLE 177

Query: 538  GNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKF 717
             N TF  VA   R+ + F++ +      D  KK+ +       P+YL+V+P +  E + +
Sbjct: 178  SNTTFYGVAGTLREKFTFVSTKST----DYAKKYTS----DSTPAYLLVRPGE--EPSVY 227

Query: 718  DGKKIDAESLTEFIGVEAVPYFGEINQDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTK 897
             G+++D   L  +I +E+ P FG+I+  T+ +Y  + +P+AYYFY N EQR A AD +  
Sbjct: 228  SGEELDETHLVHWIDIESKPLFGDIDGSTFKSYAEANIPLAYYFYENEEQRAAAADIIKP 287

Query: 898  LGKKYRGKLNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ-TDYPEGPS 1074
              K+ RGK+N VGLDA  FG+HA+ +NMD E +PLF IH +  NKKFGV Q  +      
Sbjct: 288  FAKEQRGKINFVGLDAVKFGKHAKNLNMDEEKLPLFVIHDLVSNKKFGVPQDQELTNKDV 347

Query: 1075 FKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYY 1254
             ++IEKF+    A +  PI+KSEP+P  +E+    V KLV   + +V+    KDV VKYY
Sbjct: 348  TELIEKFI----AGEAEPIVKSEPIPEIQEEK---VFKLVGKAHDEVVFDESKDVLVKYY 400

Query: 1255 APWCGHCKKLAPTWEELAEIFGSN-XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPA 1431
            APWCGHCK++AP +EELA ++ ++           +DHT NDVD   +I+GYPTL+++PA
Sbjct: 401  APWCGHCKRMAPAYEELATLYANDEDASSKVVIAKLDHTLNDVD-NVDIQGYPTLILYPA 459

Query: 1432 NGKVDEKTGIREPIVFEGPRELDTLIEFIKEKGALNVDGAELKAKLDEQKA 1584
              K         P +++G R+L++L EF+KE+G   VD   L+   +E++A
Sbjct: 460  GDK-------SNPQLYDGSRDLESLAEFVKERGTHKVDALALRPVEEEKEA 503


>Q9Y8F3|PDI1|Q9Y8F3 (TrEMBL: Kluyveromyces marxianus (Yeast)
            (Kluyveromyces fragilis)) Protein disulfide isomerase
            (Fragment).
          Length = 520

 Score =  389 bits (1000), Expect = e-107
 Identities = 224/518 (43%), Positives = 298/518 (57%), Gaps = 9/518 (1%)
 Frame = +1

Query: 31   LATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCK 210
            LATL+AV      +     +A A  +SAV+KLTSE F  FI+E+PL+LAEF+APWCG+CK
Sbjct: 11   LATLMAV------NAAAQEEATAPEDSAVIKLTSETFEDFIKEHPLVLAEFYAPWCGHCK 64

Query: 211  MLGPEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQ 390
             L PEY KAAD L +    I LAQIDCTE++ LC E GI GYP+L + R+G+SK A +YQ
Sbjct: 65   HLAPEYVKAADELEDKD--IPLAQIDCTENQQLCQEQGIPGYPSLNVFRNGNSKPAGEYQ 122

Query: 391  GPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQ 570
            GPREA  I +YM+KQS PAV+  E  +E   L+       ++        N TF ++A+ 
Sbjct: 123  GPREAKAIVNYMLKQSEPAVRVIEDEKEFKELVVKNLDNVLVVDGNVPKFNETFYQIADN 182

Query: 571  KRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLT 750
             R DY FI                     GK   YL   PK+ + +  +DG K DAE+++
Sbjct: 183  LRDDYSFIQHGSD----------------GKLRVYL---PKETEPIV-YDGDKYDAEAVS 222

Query: 751  EFIGVEAVPYFGEINQDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNI 930
             +I VEA PYFG++N +TY  YM + +P+AY+FY   E+RE        L KKYRGK+N 
Sbjct: 223  SWIAVEAFPYFGDVNGETYQAYMAAKIPLAYFFYTTPEEREEYEPHFVALAKKYRGKVNF 282

Query: 931  VGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ--------TDYPEGPSFKVI 1086
             GLDAS FGRHAE +N   +  PLFAIH    + K+G+ Q         + P   + K I
Sbjct: 283  AGLDASKFGRHAENLN-HMQQFPLFAIHDTVKDLKYGLPQLSDEDFAALEKPLKLATKDI 341

Query: 1087 EKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWC 1266
            EKFV D+  + + PI+KSE +P   EK      K+V  N+ +++    KDV VKYYAPWC
Sbjct: 342  EKFVKDFLDEAVDPIVKSEEIP---EKQEQYTFKIVGKNHDEIVRDPKKDVLVKYYAPWC 398

Query: 1267 GHCKKLAPTWEELAE-IFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKV 1443
            GHCK+LAP +E +AE +  +           ID T NDV     I G+P + ++PA  K 
Sbjct: 399  GHCKRLAPIYENMAEFVHEAEELKDKVLIANIDATANDVQ-NVEIPGFPAIYLWPAGEK- 456

Query: 1444 DEKTGIREPIVFEGPRELDTLIEFIKEKGALNVDGAEL 1557
                   EPI FEGPR ++  + FIKE G   VDG  L
Sbjct: 457  ------SEPIPFEGPRTIEAFLTFIKENGTNGVDGVSL 488



 Score = 57.4 bits (137), Expect = 5e-07
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
 Frame = +1

Query: 169 ILAEFFAPWCGYCKMLGPEYSKAADSLNESHP---KIKLAQIDCTEDEALCMEHGIRGYP 339
           +L +++APWCG+CK L P Y   A+ ++E+     K+ +A ID T ++   +E  I G+P
Sbjct: 389 VLVKYYAPWCGHCKRLAPIYENMAEFVHEAEELKDKVLIANIDATANDVQNVE--IPGFP 446

Query: 340 TLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEE 474
            + +   G+      ++GPR       ++ +     V     +EE
Sbjct: 447 AIYLWPAGEKSEPIPFEGPRTIEAFLTFIKENGTNGVDGVSLYEE 491


>Q9URT0|PDI1|Q9URT0 (TrEMBL: Kluyveromyces lactis (Yeast)) Protein
            disulfide isomerase (EC 5.3.4.1).
          Length = 527

 Score =  377 bits (967), Expect = e-103
 Identities = 221/530 (41%), Positives = 302/530 (56%), Gaps = 18/530 (3%)
 Frame = +1

Query: 49   VVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEY 228
            + ++  AS    GDAVA  +SAVVKL ++ F  FI+E+PL+LAEFFAPWCG+CK L PEY
Sbjct: 11   LAALMAASCSAQGDAVAPEDSAVVKLDADTFHEFIKEHPLVLAEFFAPWCGHCKTLAPEY 70

Query: 229  SKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAA 408
             KAAD L      I LAQIDC E++  C E GI GYP+LK+ ++G+ + A +YQG R+A 
Sbjct: 71   VKAADELESKD--IPLAQIDCQENQQFCQEQGIPGYPSLKLFKNGNPEAAGEYQGGRDAK 128

Query: 409  GIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRKDYV 588
             I +YM+KQS PAVQ  E  +  + +I        +      + N TF +VA+  R DY 
Sbjct: 129  AIVNYMLKQSEPAVQVVEDEKAFNEIIAKNLDNTYVVDGSVPEFNETFYQVADSLRDDYS 188

Query: 589  FINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVE 768
            FI                     GK   YL   P + + +  ++G+  DAE+++ +I VE
Sbjct: 189  FIQHGSD----------------GKLSIYL---PGESEPIV-YEGEDFDAETISTWIAVE 228

Query: 769  AVPYFGEINQDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDAS 948
            A PYFG++N +TY  YM   +P+AY+FY + E+RE        L KK+RGK+N  GLDAS
Sbjct: 229  AFPYFGDVNGETYQAYMAVKVPLAYFFYTSPEEREEYESHFVDLAKKFRGKVNFAGLDAS 288

Query: 949  LFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ--------TDYPEGPSFKVIEKFVAD 1104
             FGRHAE +N   +  PLFAIH    + K+G+ Q         + P   + + I KFV D
Sbjct: 289  KFGRHAENLNQKQQ-FPLFAIHDTIKDLKYGLPQLADEEFAALEKPITLATEEITKFVED 347

Query: 1105 YFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKL 1284
            +   K  PI+KSE +P  +E   N V K+V  N+++++    KDV V+YYAPWCGHCKKL
Sbjct: 348  FLEGKAEPIVKSEEIPEIQE---NSVFKIVGKNHEEIVRDPKKDVLVEYYAPWCGHCKKL 404

Query: 1285 APTWEELAEIFGSN-XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGI 1461
            APT+E +AE    N           ID T NDV     I G+P L ++PA     E+T  
Sbjct: 405  APTYESMAEFAHENDELKDKVLIAKIDATANDVQ-SVEIPGFPVLYLWPAG----EET-- 457

Query: 1462 REPIVFEGPRELDTLIEFIKEKGALNVDGAEL---------KAKLDEQKA 1584
             EPI+FEGPR  +  + FIKE G+  VDG  L         K K +E++A
Sbjct: 458  -EPILFEGPRTAEAFLAFIKENGSHGVDGLALYEEYLVEVEKKKQEEEEA 506


>P17967|PDI1|PDI_YEAST (SP: Saccharomyces cerevisiae (Baker's yeast))
            Protein disulfide isomerase precursor (PDI) (EC 5.3.4.1)
            (Thioredoxin-related glycoprotein 1).
          Length = 522

 Score =  357 bits (915), Expect = 3e-97
 Identities = 209/513 (40%), Positives = 296/513 (57%), Gaps = 14/513 (2%)
 Frame = +1

Query: 88   DAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPK 267
            +AVA  +SAVVKL +++F  +I+ + L+LAEFFAPWCG+CK + PEY KAA++L E +  
Sbjct: 25   EAVAPEDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKN-- 82

Query: 268  IKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPA 447
            I LAQIDCTE++ LCMEH I G+P+LKI ++ D   + DY+GPR A  I  +MIKQS PA
Sbjct: 83   ITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPA 142

Query: 448  VQFPETFEELDTLIDAQT--KPFVLQINPTE-DGNATFNKVANQKRKDYVFINVEDKQII 618
            V       +L   +  +T   P ++Q    + D NATF  +AN+   DY F++ E     
Sbjct: 143  VA---VVADLPAYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSAE----- 194

Query: 619  KDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKID---AESLTEFIGVEAVPYFGE 789
                    N D   K   YL   P   DE   ++GKK D   A+   +++ VEA+PYFGE
Sbjct: 195  --------NADDDFKLSIYL---PSAMDEPVVYNGKKADIADADVFEKWLQVEALPYFGE 243

Query: 790  INQDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAE 969
            I+   +  Y+ S LP+ Y FYN+ E+ E      T+L KK RG +N V +DA  FGRHA 
Sbjct: 244  IDGSVFAQYVESGLPLGYLFYNDEEELEEYKPLFTELAKKNRGLMNFVSIDARKFGRHAG 303

Query: 970  VINMDPEVVPLFAIHHISDNKKFGVNQTDYPEGPSF--------KVIEKFVADYFADKLT 1125
             +NM  E  PLFAIH ++++ K+G+ Q                 K IE  V D+     +
Sbjct: 304  NLNM-KEQFPLFAIHDMTEDLKYGLPQLSEEAFDELSDKIVLESKAIESLVKDFLKGDAS 362

Query: 1126 PIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEEL 1305
            PI+KS+ +   ++ S   V +LV  N+ +++    KDV V YYAPWCGHCK+LAPT++EL
Sbjct: 363  PIVKSQEIFENQDSS---VFQLVGKNHDEIVNDPKKDVLVLYYAPWCGHCKRLAPTYQEL 419

Query: 1306 AEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEG 1485
            A+ + +           +DHT NDV     IEGYPT++++P   K        E +V++G
Sbjct: 420  ADTYAN--ATSDVLIAKLDHTENDVR-GVVIEGYPTIVLYPGGKK-------SESVVYQG 469

Query: 1486 PRELDTLIEFIKEKGALNVDGAELKAKLDEQKA 1584
             R LD+L +FIKE G  +VDG  L  +  E+ A
Sbjct: 470  SRSLDSLFDFIKENGHFDVDGKALYEEAQEKAA 502


>O74568|PDI1|O74568 (TrEMBL: Trichoderma reesei (Hypocrea jecorina))
            Protein disulphide isomerase precursor.
          Length = 502

 Score =  346 bits (888), Expect = 4e-94
 Identities = 199/500 (39%), Positives = 276/500 (55%), Gaps = 4/500 (0%)
 Frame = +1

Query: 91   AVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKI 270
            AV    S V  LT + F  FI  N L+LAE FAPWCG+CK L PEY +AA +L +    I
Sbjct: 16   AVVSAESDVKSLTKDTFNDFINSNDLVLAESFAPWCGHCKALAPEYEEAATTLKDK--SI 73

Query: 271  KLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAV 450
            KLA++DC E+  LC EHG+ GYPTLK+ R  D      Y GPR+A GI  YM+KQSLPAV
Sbjct: 74   KLAKVDCVEEADLCKEHGVEGYPTLKVFRGLDK--VAPYTGPRKADGITSYMVKQSLPAV 131

Query: 451  QFPETFEELDTLIDAQTKPFVLQIN----PTEDGNATFNKVANQKRKDYVFINVEDKQII 618
                     DTL D +T   V+ +       +  N TF  +AN+ R  Y+F  V D  + 
Sbjct: 132  SALTK----DTLEDFKTADKVVLVAYIAADDKASNETFTALANELRDTYLFGGVNDAAVA 187

Query: 619  KDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQ 798
            +    KF ++           V  K FDE      +K DAE++  F  V A P  GE+  
Sbjct: 188  EAEGVKFPSI-----------VLYKSFDEGKNVFSEKFDAEAIRNFAQVAATPLVGEVGP 236

Query: 799  DTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVIN 978
            +TY  YM++ +P+AY F   AE+RE +A  L  + +KY+GK+N   +DA  FG HA  IN
Sbjct: 237  ETYAGYMSAGIPLAYIFAETAEERENLAKTLKPVAEKYKGKINFATIDAKNFGSHAGNIN 296

Query: 979  MDPEVVPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTE 1158
            +  +  P FAIH I  N KF  +Q+   +  + K I  FV  + + K+   IKSEP+P  
Sbjct: 297  LKTDKFPAFAIHDIEKNLKFPFDQS---KEITEKDIAAFVDGFSSGKIEASIKSEPIPET 353

Query: 1159 EEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXX 1338
            +E    PV  +VAH+YKD++    KDV +++Y PWCGHCK LAP ++ELA ++  +    
Sbjct: 354  QE---GPVTVVVAHSYKDIVLDDKKDVLIEFYTPWCGHCKALAPKYDELASLYAKSDFKD 410

Query: 1339 XXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFI 1518
                  +D T N  DVP  I+G+PT+ ++PA  K       + P+ + G R ++  IEFI
Sbjct: 411  KVVIAKVDATAN--DVPDEIQGFPTIKLYPAGDK-------KNPVTYSGARTVEDFIEFI 461

Query: 1519 KEKGALNVDGAELKAKLDEQ 1578
            KE G     G E+ A+  E+
Sbjct: 462  KENGKYKA-GVEIPAEPTEE 480


>Q00248|PDIA|PDI_ASPOR (SP: Aspergillus oryzae) Protein disulfide
            isomerase precursor (EC 5.3.4.1) (PDI).
          Length = 515

 Score =  341 bits (875), Expect = 1e-92
 Identities = 199/514 (38%), Positives = 290/514 (56%), Gaps = 4/514 (0%)
 Frame = +1

Query: 49   VVSITHASGPTDG-DAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPE 225
            ++S+  AS      DA A+  S VV LT + F +F++E+ L+LAEFFAPWCG+CK L P+
Sbjct: 8    ILSLLGASAVASAADATAEAPSDVVSLTGDTFETFVKEHDLVLAEFFAPWCGHCKALAPK 67

Query: 226  YSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREA 405
            Y +AA  L E +  I L ++DCTE+EALC + G+ GYPTLKI R  D+   + YQG R+ 
Sbjct: 68   YEQAATELKEKN--IPLVKVDCTEEEALCRDQGVEGYPTLKIFRGLDA--VKPYQGARQT 123

Query: 406  AGIADYMIKQSLPAVQ--FPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRK 579
              I  YM+KQSLPAV    PE  EE+ T+       ++   + T   N  F   A  +R 
Sbjct: 124  EAIVSYMVKQSLPAVSPVTPENLEEIKTMDKIVVIGYIASDDQT--ANDIFTTFAESQRD 181

Query: 580  DYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEV-AKFDGKKIDAESLTEF 756
            +Y+F    D  I K    K         +PS  +V  K FDE  A +DG+ I+ ++L  +
Sbjct: 182  NYLFAATSDASIAKAEGVK---------QPS--IVLYKDFDEKKATYDGE-IEQDALLSW 229

Query: 757  IGVEAVPYFGEINQDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVG 936
            +   + P  GE+  +TY  Y+T+ +P+AY F    E+RE   ++   + +K++G +NIV 
Sbjct: 230  VKTASTPLVGELGPETYSGYITAGIPLAYIFAETKEEREQFTEEFKFIAEKHKGSINIVT 289

Query: 937  LDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFAD 1116
            +DA L+G HA  +N+DP   P FAI     N K+  +Q+   +    K I KF+ D   D
Sbjct: 290  IDAKLYGAHAGNLNLDPSKFPAFAIQDPEKNAKYPYDQSKEVKA---KDIGKFIQDVLDD 346

Query: 1117 KLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTW 1296
            K+ P IKSE +P  +E    PV  +VAH+YKD++   +KDV +++YAPWCGHCK LAP +
Sbjct: 347  KVEPSIKSEAIPETQE---GPVTVVVAHSYKDLVLDNEKDVLLEFYAPWCGHCKALAPKY 403

Query: 1297 EELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIV 1476
            EELA ++             ID T N  DVP +I G+PT+ +F A  K         P+ 
Sbjct: 404  EELASLY---KDIPEVTIAKIDATAN--DVPDSITGFPTIKLFAAGAK-------DSPVE 451

Query: 1477 FEGPRELDTLIEFIKEKGALNVDGAELKAKLDEQ 1578
            +EG R ++ L  F+KE G   VD  E+  K +++
Sbjct: 452  YEGSRTVEDLANFVKENGKHKVDALEVDPKKEQE 485


>P55059||PDI_HUMIN (SP: Humicola insolens) Protein disulfide isomerase
            precursor (EC 5.3.4.1) (PDI).
          Length = 505

 Score =  332 bits (850), Expect = 1e-89
 Identities = 188/498 (37%), Positives = 280/498 (56%), Gaps = 5/498 (1%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQID 288
            S VV+L  + F  FI+ N L+LAEFFAPWCG+CK L PEY +AA +L E +  IKLA++D
Sbjct: 21   SDVVQLKKDTFDDFIKTNDLVLAEFFAPWCGHCKALAPEYEEAATTLKEKN--IKLAKVD 78

Query: 289  CTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETF 468
            CTE+  LC +HG+ GYPTLK+ R  D+     Y+G R+AA I  YMIKQSLPAV    T 
Sbjct: 79   CTEETDLCQQHGVEGYPTLKVFRGLDN--VSPYKGQRKAAAITSYMIKQSLPAVS-EVTK 135

Query: 469  EELDTLIDAQTKPFVLQINPTEDGNA-TFNKVANQKRKDYVFINVEDKQIIKDLNKKFKN 645
            + L+    A     V  ++ ++  ++  F +VA + R +Y F +  D  +          
Sbjct: 136  DNLEEFKKADKAVLVAYVDASDKASSEVFTQVAEKLRDNYPFGSSSDAAL---------- 185

Query: 646  VDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTYMTS 825
             +  G K   +V+  K FDE      +K + E++ +F    A P  GEI  +TY  YM++
Sbjct: 186  AEAEGVKAPAIVLY-KDFDEGKAVFSEKFEVEAIEKFAKTGATPLIGEIGPETYSDYMSA 244

Query: 826  PLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINMDPEVVPLF 1005
             +P+AY F   AE+R+ ++D L  + +  RG +N   +DA  FG HA  +N+  +  P F
Sbjct: 245  GIPLAYIFAETAEERKELSDKLKPIAEAQRGVINFGTIDAKAFGAHAGNLNLKTDKFPAF 304

Query: 1006 AIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVV 1185
            AI  ++ N+KF  +Q    +  +F+ I+ FV D+ A K+ P IKSEP+P   EK   PV 
Sbjct: 305  AIQEVAKNQKFPFDQ---EKEITFEAIKAFVDDFVAGKIEPSIKSEPIP---EKQEGPVT 358

Query: 1186 KLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDH 1365
             +VA NY +++    KDV +++YAPWCGHCK LAP +EEL  ++  +          +D 
Sbjct: 359  VVVAKNYNEIVLDDTKDVLIEFYAPWCGHCKALAPKYEELGALYAKSEFKDRVVIAKVDA 418

Query: 1366 TNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEKG----A 1533
            T N  DVP  I+G+PT+ ++PA  K        +P+ + G R ++ LI+FI E G    A
Sbjct: 419  TAN--DVPDEIQGFPTIKLYPAGAK-------GQPVTYSGSRTVEDLIKFIAENGKYKAA 469

Query: 1534 LNVDGAELKAKLDEQKAT 1587
            ++ D  E  +  +    T
Sbjct: 470  ISEDAEETSSATETTTET 487


>Q12730|PDIA|PDI_ASPNG (SP: Aspergillus niger) Protein disulfide
            isomerase precursor (EC 5.3.4.1) (PDI).
          Length = 515

 Score =  328 bits (840), Expect = 2e-88
 Identities = 193/498 (38%), Positives = 276/498 (55%), Gaps = 6/498 (1%)
 Frame = +1

Query: 91   AVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKI 270
            A AD  S V+ L  + F SF+ E+ L+LAEFFAPWCG+CK L P+Y +AA  L   +  I
Sbjct: 19   AAADTESDVISLDQDTFESFMNEHGLVLAEFFAPWCGHCKALAPKYEEAATELKAKN--I 76

Query: 271  KLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAV 450
             L ++DCT +E LC   G+ GYPTLKI R  DS  ++ YQG R+   I  YMIKQSLPAV
Sbjct: 77   PLVKVDCTAEEDLCRSQGVEGYPTLKIFRGVDS--SKPYQGARQTESIVSYMIKQSLPAV 134

Query: 451  QF--PETFEELDTLIDAQTKPFVLQINPTEDGNA--TFNKVANQKRKDYVFINVEDKQII 618
                 E  EE+ T+     K  V+   P++D      F K A  +R +Y+F   +D  I 
Sbjct: 135  SSVNEENLEEIKTM----DKIVVIGYIPSDDQETYQAFEKYAESQRDNYLFAATDDAAIA 190

Query: 619  KDLNKKFKNVDITGKKPSYLVVQPKQFDEV-AKFDGKKIDAESLTEFIGVEAVPYFGEIN 795
            K    +         +PS  +V  K FDE  A +DG+ I+ E++  ++   + P  GEI 
Sbjct: 191  KSEGVE---------QPS--IVLYKDFDEKKAVYDGE-IEQEAIHSWVKSASTPLVGEIG 238

Query: 796  QDTYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVI 975
             +TY  Y+ + +P+AY F    E+RE   +D   + +K++G +NI  +DA +FG HA  +
Sbjct: 239  PETYSGYIGAGVPLAYIFAETKEEREKYTEDFKPIAQKHKGAINIATIDAKMFGAHAGNL 298

Query: 976  NMDPEVVPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPT 1155
            N+D +  P FAI   + N K+  +Q           +EKF+ D    K+ P IKSEP+P 
Sbjct: 299  NLDSQKFPAFAIQDPAKNAKYPYDQAKELNADE---VEKFIQDVLDGKVEPSIKSEPVPE 355

Query: 1156 EEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN-XX 1332
             +E    PV  +VAH+YKD++   DKDV +++YAPWCGHCK LAP ++ELA ++  +   
Sbjct: 356  SQE---GPVTVVVAHSYKDLVIDNDKDVLLEFYAPWCGHCKALAPKYDELAALYADHPDL 412

Query: 1333 XXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIE 1512
                    ID T NDV  P  I G+PTL ++PA  K         PI + G R ++ L  
Sbjct: 413  AAKVTIAKIDATANDVPDP--ITGFPTLRLYPAGAK-------DSPIEYSGSRTVEDLAN 463

Query: 1513 FIKEKGALNVDGAELKAK 1566
            F+KE G  NVD   + ++
Sbjct: 464  FVKENGKHNVDALNVASE 481


>Q10057|SPAC1F5.02|PDI1_SCHPO (SP: Schizosaccharomyces pombe (Fission
            yeast)) Putative protein disulfide isomerase C1F5.02
            precursor (EC 5.3.4.1).
          Length = 492

 Score =  285 bits (728), Expect = 2e-75
 Identities = 169/477 (35%), Positives = 253/477 (53%), Gaps = 6/477 (1%)
 Frame = +1

Query: 106  NSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQI 285
            ++ V K+  E     I  + +++ +F+APWCG+CK L PEY  AAD L +    I L ++
Sbjct: 21   SAEVPKVNKEGLNELITADKVLMVKFYAPWCGHCKALAPEYESAADELEKDG--ISLVEV 78

Query: 286  DCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPET 465
            DCTE+  LC E+ IRGYPTL + ++G  K    Y GPR+   +  YM KQ LP V+ P +
Sbjct: 79   DCTEEGDLCSEYSIRGYPTLNVFKNG--KQISQYSGPRKHDALVKYMRKQLLPTVK-PIS 135

Query: 466  FEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKN 645
             + L+  ++      V+     +  N T+ +VA   + D+VF   +DK++ K L   F  
Sbjct: 136  KDTLENFVEKADDLAVVAFFKDQKLNDTYTEVAEVMKDDFVFAASDDKELAKSLGSNFPG 195

Query: 646  VDITGKKPSYLVVQPKQFDEVAKFDGKKI------DAESLTEFIGVEAVPYFGEINQDTY 807
            +                F + A  D  K+      D  S+ +FIGV ++P   E+NQ T+
Sbjct: 196  I--------------VAFTKDAAQDSDKLVYTGDWDPASIADFIGVSSIPLLDELNQMTF 241

Query: 808  MTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINMDP 987
              Y  S LP+   FYN+ E R+ + D    L KKY+  L    LDA  +G  A+ +N++ 
Sbjct: 242  GKYQQSGLPLGIIFYNSTESRDELYDVFQPLAKKYQDTLRFAFLDAVRYGAVAKQMNVES 301

Query: 988  EVVPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEK 1167
            +  P F I ++    K+    T+     + K + KFV D+   KL P IKS+P+P  +E 
Sbjct: 302  DW-PAFVIANLKSMLKYPFPTTEL----TAKAMTKFVGDFVDGKLQPKIKSQPIPESQED 356

Query: 1168 SANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXX 1347
                +V LVA N+ D++    KDV V++YAPWCGHCK LAPT+E+LAE +  +       
Sbjct: 357  ----LVVLVADNFDDIVMDETKDVLVEFYAPWCGHCKNLAPTYEKLAEEYSDD---SNVV 409

Query: 1348 XXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFI 1518
               ID T ND+ V  +I G+PT++ F AN KV+       P+ +EG R L+ L  FI
Sbjct: 410  VAKIDATENDISV--SISGFPTIMFFKANDKVN-------PVRYEGDRTLEDLSAFI 457



 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 34/116 (29%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
 Frame = +1

Query: 94  VADPNSAVVKLTSENFASFI-EENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKI 270
           + +    +V L ++NF   + +E   +L EF+APWCG+CK L P Y K A+  ++    +
Sbjct: 350 IPESQEDLVVLVADNFDDIVMDETKDVLVEFYAPWCGHCKNLAPTYEKLAEEYSDDS-NV 408

Query: 271 KLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
            +A+ID TE++   +   I G+PT+   +  D      Y+G R    ++ ++ K +
Sbjct: 409 VVAKIDATEND---ISVSISGFPTIMFFKANDKVNPVRYEGDRTLEDLSAFIDKHA 461


>P32474|EUG1|EUG1_YEAST (SP: Saccharomyces cerevisiae (Baker's yeast))
            Protein disulfide isomerase EUG1 precursor (PDI) (EC
            5.3.4.1) (Endoplasmic reticulum protein EUG1).
          Length = 517

 Score =  281 bits (720), Expect = 1e-74
 Identities = 170/509 (33%), Positives = 274/509 (53%), Gaps = 9/509 (1%)
 Frame = +1

Query: 82   DGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
            +  A A P S ++ LT + F SFIE +PL+L EFFAPWC + ++L P   +AA  L E +
Sbjct: 24   ENSARATPGSDLLVLTEKKFKSFIESHPLVLVEFFAPWCLHSQILRPHLEEAASILKEHN 83

Query: 262  PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSL 441
              + + QIDC  +  +C++  I  YPTLKI ++G     + Y+G +    I  YMI+   
Sbjct: 84   --VPVVQIDCEANSMVCLQQTINTYPTLKIFKNGRIFDGQVYRGVKITDEITQYMIQLYE 141

Query: 442  PAVQFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIK 621
             +V +  + +E+   ++  T P V+    T   N T+ +VA    +DYVF+++ D +  K
Sbjct: 142  ASVIYLNSEDEIQPYLENATLPVVINRGLT-GLNETYQEVALDLAEDYVFLSLLDSED-K 199

Query: 622  DLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQD 801
             L+    N             +P  FD     D    ++ +LT+++ V  +PYF +I  D
Sbjct: 200  SLSIHLPNT-----------TEPILFD--GNVDSLVGNSVALTQWLKVVILPYFTDIEPD 246

Query: 802  TYMTYMTSPLPIAYYFYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINM 981
             +  Y++S LP+AY+FY + E+ E   D  T+LGK+ RG++N + L++++F  H   +NM
Sbjct: 247  LFPKYISSNLPLAYFFYTSEEELEDYTDLFTQLGKENRGQINFIALNSTMFPHHVRFLNM 306

Query: 982  DPEVVPLFAIHHISDNKKFGVNQ--------TDYPEGPSFKVIEKFVADYFADKLTPIIK 1137
              E  PLFAIH++ +N K+G+ Q         + P+     +I + V DY      PI+K
Sbjct: 307  -REQFPLFAIHNMINNLKYGLPQLPEEEYAKLEKPQPLDRDMIVQLVKDYREGTAKPIVK 365

Query: 1138 SEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIF 1317
            SE +P E++ +   V K+V   + D++   DKDV VKYYA WC H K+ AP +EE+A + 
Sbjct: 366  SEEIPKEQKSN---VYKIVGKTHDDIVHDDDKDVLVKYYATWCIHSKRFAPIYEEIANVL 422

Query: 1318 GSN-XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRE 1494
             S+           +D   ND+ + + + GYPT+ ++PA           +PI+F   R 
Sbjct: 423  ASDESVRDKILIAEVDSGANDI-LSFPVTGYPTIALYPAGNN-------SKPIIFNKIRN 474

Query: 1495 LDTLIEFIKEKGALNVDGAELKAKLDEQK 1581
            L+ + EFIKE G  ++DG  +  KL + K
Sbjct: 475  LEDVFEFIKESGTHHIDGQAIYDKLHQAK 503


>Q96VF3||Q96VF3 (TrEMBL: Ustilago maydis (Smut fungus)) Hypothetical
            protein.
          Length = 487

 Score =  276 bits (706), Expect = 5e-73
 Identities = 168/468 (35%), Positives = 253/468 (54%), Gaps = 10/468 (2%)
 Frame = +1

Query: 157  ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGY 336
            + PL+L EF+APWCG+CK L PEY KA+  L     KIKLA++DCTE+  LC EHG+ G+
Sbjct: 29   QQPLMLVEFYAPWCGHCKALAPEYEKASTELLAD--KIKLAKVDCTEENELCAEHGVEGF 86

Query: 337  PTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEEL--DTLIDAQTKPF 510
            PTLK+ R G S    +Y G R+A GI  YM KQ+LPA+       EL  D+  D ++K  
Sbjct: 87   PTLKVFRTGSSS---EYNGNRKADGIVSYMKKQALPALS------ELTADSYADFKSKDR 137

Query: 511  VLQINPTEDGNATF----NKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYL 678
            V+ I   +  +       N VAN  R +Y+F  V D  + +          +T   P+++
Sbjct: 138  VVAIAYLDSSDKAHLDAVNAVANNLRDNYLFGVVHDAAVAE-------KAGVTA--PAFV 188

Query: 679  VVQPKQFDEV-AKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTYMTSPLPIAYYFYN 855
            V   +QFDE   KFDGK  + E++T FI  E++P   E+N + +M+Y  S LP+AY F +
Sbjct: 189  VY--RQFDEPEVKFDGKSFNEEAITNFIKAESIPLIDELNAENFMSYAESGLPLAYLFAD 246

Query: 856  -NAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNK 1032
              ++  ++  + L  L +  +GKLN V +D   +  HA+ +N+  E  P FA+  I  N 
Sbjct: 247  PESKDLKSTVESLKSLARANKGKLNFVWIDGVKYSAHAKSLNIQGEDWPAFAVQDIEQNL 306

Query: 1033 KFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKD 1212
            KF +       G     +  FV+ Y +  L P +KSEP+P +++    PV  LVA  +  
Sbjct: 307  KFPLEDLS---GDLVAKVTDFVSQYTSGSLKPSVKSEPIPKDQD---GPVHVLVADEFDA 360

Query: 1213 VLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDV--DV 1386
            V+    KD  V++YAPWCGHCKKLAPT++ L E + ++          +D T ND+    
Sbjct: 361  VIGDDSKDKLVEFYAPWCGHCKKLAPTYDTLGEKYKAH--KDKVLIAKMDATANDIPPSA 418

Query: 1387 PYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEKG 1530
             + ++ +PT+          +  G ++ I F G R L+  ++FI   G
Sbjct: 419  GFQVQSFPTIKF--------QAAGSKDWIEFTGERSLEGFVDFIALNG 458


>Q91Z81||Q91Z81 (TrEMBL: Cricetulus griseus (Chinese hamster)) ERP57
            protein.
          Length = 505

 Score =  231 bits (590), Expect = 2e-59
 Identities = 157/487 (32%), Positives = 242/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT ENF S + +     L+L EFFAPWCG+CK L PEY  AA  L    P   L 
Sbjct: 25   SDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LT 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVLL 139

Query: 460  ETFEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
             + EE    I   DA    F   +    DG++ F K A+  R +Y F +   + ++K+ +
Sbjct: 140  RSEEEFKKFISDKDASVVGFFRDL--FSDGHSEFLKAASNLRDNYRFAHTNVESLVKEYD 197

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + +   +PS+L    K  D+   +  +K+ +  +  FI          + +D   
Sbjct: 198  DNGEGITLF--RPSHLA--NKFEDKTVVYTEQKMTSGKIKRFIQESIFGICPHMTEDNKD 253

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
               +  L  AYY   +  NA+      + +  + KK+     KLN        F      
Sbjct: 254  LIQSKDLLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSD 313

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
              ++     VP+ AI   +  +KF + +    +G   K +E+F+ DYF   L   +KSEP
Sbjct: 314  FGLESTTGEVPVVAIR-TAKGEKFVMQEEFSRDG---KALERFLQDYFDGNLKRYLKSEP 369

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA N+ D++   DKDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 370  IP---ETNDGPVKVVVAENFDDIVNNEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD 426

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY ++G+PT+   PAN K++ K        +EG REL+  
Sbjct: 427  ---PNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLNPKK-------YEGGRELNDF 476

Query: 1507 IEFIKEK 1527
            I +++ +
Sbjct: 477  INYLQRE 483



 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 34/119 (28%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFIE-ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   +  E+  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 368 EPIPETNDGPVKVVVAENFDDIVNNEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +   + ++G+PT+           + Y+G RE     +Y+ +++
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVKGFPTIYFSPANKKLNPKKYEGGRELNDFINYLQREA 484


>Q8JG64|GRP58|Q8JG64 (TrEMBL: Gallus gallus (Chicken)) Glucose
            regulated thiol oxidoreductase protein precursor.
          Length = 505

 Score =  231 bits (589), Expect = 2e-59
 Identities = 164/505 (32%), Positives = 246/505 (48%), Gaps = 13/505 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP-LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQI 285
            S VV+L+  +F S + E P L+L EFFAPWCG+CK L PEY  AA  L    P +K   +
Sbjct: 25   SDVVELSDADFESGLAERPGLVLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLVK---V 81

Query: 286  DCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPET 465
            DCT +   C ++G+ GYPTLKI RDG+      Y GPR A GI  ++ KQ+ PA     +
Sbjct: 82   DCTANSNTCNKYGVSGYPTLKIFRDGEESGT--YDGPRTADGIVSHLKKQAGPASVALSS 139

Query: 466  FEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKK 636
              + +  I   DA    F    + + D  + F K AN  R +Y F +  ++Q+++   + 
Sbjct: 140  VADFEKFIGDKDASVVGFFR--DASGDAYSEFMKAANNLRDNYRFAHTSEEQLVQKYEED 197

Query: 637  FKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTY 816
             + V +   +PS L    K  D   K+   KI +  + +FI          + +D     
Sbjct: 198  GEGVVLY--RPSRLA--NKFEDSTVKYTEDKITSAKIKKFIQENIFGICPHMTEDNKDLI 253

Query: 817  MTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEVIN 978
                L +AYY   +  NA+      + +  + KK+     KL+        FG       
Sbjct: 254  QGKDLLVAYYDVDYEKNAKGSNYWRNRVMMIAKKFLDAGHKLSFAVASRKTFGHELSEFG 313

Query: 979  MDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLP 1152
            +D  V   P+ AI   +   KF + +    +G   K +E+F+ DYF   L   +KSEP+P
Sbjct: 314  LDNSVGEAPVVAIR-TAKGDKFVMQEEFSRDG---KALERFLQDYFDGNLKKYLKSEPVP 369

Query: 1153 TEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXX 1332
               E +  PV  +VA N+ +++   DKDV +++YAPWCGHCK L P ++EL E    +  
Sbjct: 370  ---ENNDGPVKVVVAENFDEIVNAEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD-- 424

Query: 1333 XXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIE 1512
                    +D T NDV  PY + G+PT+   PA  K       + P  +EG RE+   I 
Sbjct: 425  -PNIVIAKMDATANDVPSPYEVRGFPTIYFAPAGKK-------QSPKKYEGGREVSDFIS 476

Query: 1513 FIK-EKGALNVDGAELKAKLDEQKA 1584
            ++K E  +  V   E KAK  ++KA
Sbjct: 477  YLKREATSTPVLQEEDKAKKSKKKA 501



 Score = 60.1 bits (144), Expect = 8e-08
 Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 1/120 (0%)
 Frame = +1

Query: 1171 ANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXX 1350
            A+ VV+L   +++  L +    V V+++APWCGHCK+LAP +E  A              
Sbjct: 24   ASDVVELSDADFESGLAERPGLVLVEFFAPWCGHCKRLAPEYEAAA-----TRLKGIVPL 78

Query: 1351 XXIDHT-NNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEK 1527
              +D T N++    Y + GYPTL +F    +  E++G      ++GPR  D ++  +K++
Sbjct: 79   VKVDCTANSNTCNKYGVSGYPTLKIF----RDGEESG-----TYDGPRTADGIVSHLKKQ 129


>Q99LF6|GRP58|Q99LF6 (TrEMBL: Mus musculus (Mouse)) Similar to ER-60
            protease (Similar to glucose regulated protein, 58 kDa).
          Length = 505

 Score =  231 bits (589), Expect = 2e-59
 Identities = 159/487 (32%), Positives = 242/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT ENF S + +     L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 25   SDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LA 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 139

Query: 460  ETFEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
             T EE    I   DA    F   +    DG++ F K A+  R +Y F +   + ++K+ +
Sbjct: 140  RTEEEFKKFISDKDASVVGFFRDL--FSDGHSEFLKAASNLRDNYRFAHTNIESLVKEYD 197

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + I   +P +L    K  D+   +  KK+ +  + +FI          + +D   
Sbjct: 198  DNGEGITIF--RPLHLA--NKFEDKTVAYTEKKMTSGKIKKFIQDSIFGLCPHMTEDNKD 253

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
                  L  AYY   +  NA+      + +  + KK+     KLN        F      
Sbjct: 254  LIQGKDLLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSD 313

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
              ++     VP+ AI   +  +KF + +    +G   K +E+F+ +YF   L   +KSEP
Sbjct: 314  FGLESTTGEVPVVAIR-TAKGEKFVMQEEFSRDG---KALEQFLQEYFDGNLKRYLKSEP 369

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA N+ D++ + DKDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 370  IP---ESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD 426

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY ++G+PT+   PAN K+  K        +EG REL+  
Sbjct: 427  ---PNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKK-------YEGGRELNDF 476

Query: 1507 IEFIKEK 1527
            I +++ +
Sbjct: 477  ISYLQRE 483



 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 36/119 (30%), Positives = 68/119 (57%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFI-EENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   + EE+  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 368 EPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +   + ++G+PT+         T + Y+G RE      Y+ +++
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREA 484


>Q8C2F4|GRP58|Q8C2F4 (TrEMBL: Mus musculus (Mouse)) Glucose regulated
            protein.
          Length = 505

 Score =  231 bits (589), Expect = 2e-59
 Identities = 159/487 (32%), Positives = 242/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT ENF S + +     L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 25   SDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LA 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 139

Query: 460  ETFEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
             T EE    I   DA    F   +    DG++ F K A+  R +Y F +   + ++K+ +
Sbjct: 140  RTEEEFKKFISDKDASVVGFFRDL--FSDGHSEFLKAASNLRDNYRFAHTNIESLVKEYD 197

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + I   +P +L    K  D+   +  KK+ +  + +FI          + +D   
Sbjct: 198  DNGEGITIF--RPLHLA--NKFEDKTVAYTEKKMTSGKIKKFIQDSIFGLCPHMTEDNKD 253

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
                  L  AYY   +  NA+      + +  + KK+     KLN        F      
Sbjct: 254  LIQGKDLLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSD 313

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
              ++     VP+ AI   +  +KF + +    +G   K +E+F+ +YF   L   +KSEP
Sbjct: 314  FGLESTTGEVPVVAIR-TAKGEKFVMQEEFSRDG---KALEQFLQEYFDGNLKRYLKSEP 369

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA N+ D++ + DKDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 370  IP---ESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD 426

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY ++G+PT+   PAN K+  K        +EG REL+  
Sbjct: 427  ---PNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKK-------YEGGRELNDF 476

Query: 1507 IEFIKEK 1527
            I +++ +
Sbjct: 477  ISYLQRE 483



 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 36/119 (30%), Positives = 68/119 (57%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFI-EENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   + EE+  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 368 EPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +   + ++G+PT+         T + Y+G RE      Y+ +++
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREA 484


>Q26593||Q26593 (TrEMBL: Schistosoma mansoni (Blood fluke)) Protein
            disulfide isomerase homologue precursor.
          Length = 482

 Score =  228 bits (582), Expect = 1e-58
 Identities = 157/508 (30%), Positives = 252/508 (49%), Gaps = 6/508 (1%)
 Frame = +1

Query: 25   KVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGY 204
            K+   L+ V  +  AS  T+ D V       + L  +NF   I+ N  +L EF+APWCG+
Sbjct: 2    KLSVALVVVFLVFAASEVTEEDDV-------LVLNKKNFDDVIKTNKFVLVEFYAPWCGH 54

Query: 205  CKMLGPEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAED 384
            CK L PEYS+AA  L E    IKLA++D T +E L ++HG +GYPTLK  R   ++   D
Sbjct: 55   CKALAPEYSEAAKKLKEKGSLIKLAKVDATVEEELALKHGEKGYPTLKFFR---NEQPID 111

Query: 385  YQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTEDGN-ATFNKV 561
            + G R++  I ++ +++S P+V++ ++ +     ID      +  I  T+  + A F KV
Sbjct: 112  FLGERDSDAIVNWCLRKSKPSVEYIDSLDSCKQFIDKANIAILGFIKDTDSLDLADFEKV 171

Query: 562  ANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDE-VAKFDGKKIDA 738
            A++   D  F      +I+ +           G   +  +V  K FDE   ++ G  +  
Sbjct: 172  ADE-LDDAGFAIANSSEILTEY----------GITQTPKIVLFKNFDENRVEYTGGTL-- 218

Query: 739  ESLTEFIGVEAVPYFGEINQDTYMTYMTSPL-PIAYYFYNNAEQREAIADDLTKLGKKYR 915
            E+L  FI VE+VP   E +Q T      SP+     +F + +     + D LT++ ++++
Sbjct: 219  ENLKHFIQVESVPLVSEFSQKTAGVVFGSPIQKHIVFFLSKSTDHSDLVDKLTEVARQFK 278

Query: 916  GKLNIVGLDASLFG--RHAEVINMDPEVVPLFAIHHI-SDNKKFGVNQTDYPEGPSFKVI 1086
            GKL+++ +D  +    R  E   +     P + I  +  +  K+  +  DY    S   +
Sbjct: 279  GKLHVIYVDVDVENNLRVLEFFGLSKNDAPTYRIIELGEETTKYKPDTNDY----SVSAM 334

Query: 1087 EKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWC 1266
              FV      K+ P + SE +P+++      V  LV  NY DV++   KDVFVK YAPWC
Sbjct: 335  SDFVQRTIDGKVKPFLMSEEIPSDQ---TGAVKVLVGKNYNDVVKDKSKDVFVKLYAPWC 391

Query: 1267 GHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVD 1446
            GHCK LAP W+EL E F ++          +D T N+V+    +  +PTL  +P N +  
Sbjct: 392  GHCKALAPVWDELGETFKNS----DTVIAKMDATVNEVE-DLKVTSFPTLKFYPKNSE-- 444

Query: 1447 EKTGIREPIVFEGPRELDTLIEFIKEKG 1530
                  E I + G R  + L +F++  G
Sbjct: 445  ------EVIDYTGDRSFEALKKFVESGG 466


>O17908|H06O01.1|O17908 (TrEMBL: Caenorhabditis elegans) H06O01.1
            protein (CeERp57).
          Length = 488

 Score =  228 bits (582), Expect = 1e-58
 Identities = 149/499 (29%), Positives = 232/499 (46%), Gaps = 13/499 (2%)
 Frame = +1

Query: 91   AVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKI 270
            A A    AV++ T  NF   I+ + + L +F+APWCG+CK + PEY +AA  L  + P +
Sbjct: 14   AFASAGGAVLEYTDGNFDDLIQTHDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPV 73

Query: 271  KLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAV 450
             L ++DCT ++ +C + G++G+PTLKI R+G    A+DY GPR+A GI  +M  QS P+ 
Sbjct: 74   ALVKVDCTTEKTVCDKFGVKGFPTLKIFRNG--VPAQDYDGPRDADGIVKFMRGQSGPSS 131

Query: 451  QFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
            +  +T  E +          +           ++ KVA+ +R  + F +  +K IIK   
Sbjct: 132  KELKTVAEFEKFTGGDENVVIGFFESESKLKDSYLKVADTERDRFSFAHTSNKDIIKK-- 189

Query: 631  KKFKNVDITGKKPSYLVVQPK----QFD-EVAKFDGKKIDAESLTEFIGVEAVPYFGEIN 795
                     G     +V  PK    +FD    K+DG   D + +  F+  E V + G   
Sbjct: 190  --------AGYSDDVVVFVPKKLHNKFDTNEFKYDG-NYDTDKIKNFLVHETVGFAGIRT 240

Query: 796  QDTYMTYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHA 966
            Q     +   P+ I YY   +  + +      + + K+ + Y+ K+     +   F    
Sbjct: 241  QGNLFQFEQKPIVIVYYNVDYVKDPKGSNYWRNRVLKVAQNYKRKVQFAVSNKEEFSSEI 300

Query: 967  EVINMDPEV---VPLFAIHHISDNKKFGVNQTDYPEGPSFKV--IEKFVADYFADKLTPI 1131
            E   +        P+ AI           N+  YP    F V  +++FV +  A    P 
Sbjct: 301  ETNGLGERKDSDKPIVAIL---------TNEGKYPMDQEFSVDNLQQFVDEVLAGNAEPY 351

Query: 1132 IKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAE 1311
            +KSEP+P E+      V   V  N+K+++   DKDV +++YAPWCGHCK LAP +EELAE
Sbjct: 352  MKSEPIPDEQ----GDVKVAVGKNFKELIMDADKDVLIEFYAPWCGHCKSLAPKYEELAE 407

Query: 1312 IFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPR 1491
                           +D T NDV   + + G+PTL   P N K         PI + G R
Sbjct: 408  KLNKE----DVIIAKMDATANDVPPMFEVRGFPTLFWLPKNAK-------SNPIPYNGGR 456

Query: 1492 ELDTLIEFIKEKGALNVDG 1548
            E+   + FI +     + G
Sbjct: 457  EVKDFVSFISKHSTDGLKG 475


>P27773|GRP58|PDA3_MOUSE (SP: Mus musculus (Mouse)) Protein disulfide
            isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase
            ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).
          Length = 504

 Score =  228 bits (581), Expect = 2e-58
 Identities = 157/487 (32%), Positives = 242/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT ENF S + +     L+L EFFAPWCG+CK L PEY  AA  L      + LA
Sbjct: 25   SDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKI----VPLA 80

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI R G+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 81   KVDCTANTNTCNKYGVSGYPTLKIFRAGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 138

Query: 460  ETFEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
             T EE    I   DA    F   +    DG++ F K A+  R +Y F +   + ++K+ +
Sbjct: 139  RTEEEFKKFISDKDASVVGFFRDL--FSDGHSEFLKAASNLRDNYRFAHTNIESLVKEYD 196

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + I   +P +L    K  D+   +  KK+ +  + +FI          + +D   
Sbjct: 197  DNGEGITIF--RPLHLA--NKFEDKTVAYTEKKMTSAKIKKFIQDSIFGLCPHMTEDNKD 252

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
                  L  AYY   +  NA+      + +  + KK+     KLN        F      
Sbjct: 253  LIQGKDLLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSD 312

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
             +++     VP+ AI   +  +KF + +    +G   K +E+F+ +YF   L   +KSEP
Sbjct: 313  FSLESTTGEVPVVAIR-TAKGEKFVMQEEFSRDG---KALEQFLQEYFDGNLKRYLKSEP 368

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA N+ D++ + DKDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 369  IP---ESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD 425

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY ++G+PT+   PAN K+  K        +EG REL+  
Sbjct: 426  ---PNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKK-------YEGGRELNDF 475

Query: 1507 IEFIKEK 1527
            I +++ +
Sbjct: 476  ISYLQRE 482



 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 36/119 (30%), Positives = 68/119 (57%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFI-EENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   + EE+  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 367 EPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 425

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +   + ++G+PT+         T + Y+G RE      Y+ +++
Sbjct: 426 PNIVIAKMDATAND-VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREA 483


>Q9V630|ERP60|Q9V630 (TrEMBL: Drosophila melanogaster (Fruit fly))
            CG8983 protein.
          Length = 488

 Score =  225 bits (574), Expect = 1e-57
 Identities = 150/490 (30%), Positives = 243/490 (49%), Gaps = 6/490 (1%)
 Frame = +1

Query: 115  VVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCT 294
            V++L  ++FA+ ++++   L  F+APWCG+CK L PEY+KAA+ + +  P IKLA++DCT
Sbjct: 23   VLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCT 82

Query: 295  E-DEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFE 471
            E  +  C ++ + GYPTLKI R    + ++DY GPREA+GIA YM  Q  PA +   T  
Sbjct: 83   EAGKETCSKYSVSGYPTLKIFR--QDEVSQDYNGPREASGIAKYMRAQVGPASKTVRTVA 140

Query: 472  ELDTLIDAQTKPFVLQINPTEDGNA-TFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNV 648
            EL   +D +        + ++   A  F K A++ R+ Y F +  +K+++    +  K V
Sbjct: 141  ELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIV 200

Query: 649  DITGKKPSYLVVQPKQFDEVA-KFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTYMTS 825
             I     S       +F+  + KF+G       L+ F+        G   QD+   +  +
Sbjct: 201  LIRAPHLS------NKFESSSIKFEGS--SESDLSTFVKENFHGLVGHRTQDSVKDFQ-N 251

Query: 826  PLPIAYY---FYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINMDPEVV 996
            PL  AYY   +  N +      + + K+ K++ G++N        F         D    
Sbjct: 252  PLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDFVGD 311

Query: 997  PLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSAN 1176
                +     N K+ +      +  S + ++ FV    A++L P IKSEP+P   E +  
Sbjct: 312  KPVVLARDEKNLKYALK-----DEFSVENLQDFVEKLLANELEPYIKSEPIP---ESNDA 363

Query: 1177 PVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXX 1356
            PV   VA N+ D++    KD  +++YAPWCGHCKKL+P +EELAE               
Sbjct: 364  PVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAE----KLQDEDVAIVK 419

Query: 1357 IDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEKGAL 1536
            +D T NDV   +N+ G+PTL   P + K        +P+ + G RE+D  +++I ++   
Sbjct: 420  MDATANDVPPEFNVRGFPTLFWLPKDAK-------NKPVSYNGGREVDDFLKYIAKEATT 472

Query: 1537 NVDGAELKAK 1566
             + G +   K
Sbjct: 473  ELKGFDRSGK 482


>P11598|GRP58|PDA3_RAT (SP: Rattus norvegicus (Rat)) Protein disulfide
            isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase
            ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
            (HIP-70) (Q-2).
          Length = 505

 Score =  224 bits (571), Expect = 2e-57
 Identities = 154/487 (31%), Positives = 240/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT ENF S + +     L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 25   SDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LA 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 139

Query: 460  ETFEELDTLI---DAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
             T +E    I   DA    F   +    DG++ F K A+  R +Y F +   + ++K+ +
Sbjct: 140  RTEDEFKKFISDKDASVVGFFRDL--FSDGHSEFLKAASNLRDNYRFAHTNVESLVKEYD 197

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + I   +P +L    K  D++  +  KK+ +  + +FI          + +D   
Sbjct: 198  DNGEGITIF--RPLHLA--NKFEDKIVAYTEKKMTSGKIKKFIQESIFGLCPHMTEDNKD 253

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
                  L  AYY   +  N +      + +  + K +     KLN        F      
Sbjct: 254  LIQGKDLLTAYYDVDYEKNTKGSNYWRNRVMMVAKTFLDAGHKLNFAVASRKTFSHELSD 313

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
              ++     +P+ AI   +  +KF + +    +G   K +E+F+ +YF   L   +KSEP
Sbjct: 314  FGLESTTGEIPVVAIR-TAKGEKFVMQEEFSRDG---KALERFLQEYFDGNLKRYLKSEP 369

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA ++ D++   DKDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 370  IP---ETNEGPVKVVVAESFDDIVNAEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD 426

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY ++G+PT+   PAN K+  K        +EG REL+  
Sbjct: 427  ---PNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKK-------YEGGRELNDF 476

Query: 1507 IEFIKEK 1527
            I +++ +
Sbjct: 477  ISYLQRE 483



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 34/119 (28%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFIE-ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +E+F   +  E+  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 368 EPIPETNEGPVKVVVAESFDDIVNAEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +   + ++G+PT+         T + Y+G RE      Y+ +++
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREA 484


>Q7ZWU3||Q7ZWU3 (TrEMBL: Xenopus laevis (African clawed frog))
            Hypothetical protein.
          Length = 502

 Score =  223 bits (569), Expect = 4e-57
 Identities = 155/505 (30%), Positives = 246/505 (48%), Gaps = 9/505 (1%)
 Frame = +1

Query: 40   LLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLG 219
            LLAV + T A+G           S V+ LT +NF S + ++ ++L EFFAPWCG+CK L 
Sbjct: 12   LLAVTAGTQAAG-----------SDVLDLTDDNFESVVAQHSILLVEFFAPWCGHCKKLA 60

Query: 220  PEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPR 399
            PEY  AA  L  +   + LA++DCT +  +C ++G+ GYPTLKI RDG+   +  Y GPR
Sbjct: 61   PEYEIAATKLKGT---LSLAKVDCTANSNICNKYGVSGYPTLKIFRDGED--SGSYDGPR 115

Query: 400  EAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTEDG-NATFNKVANQKR 576
             A GI   M KQ+ PA     + EE +  +  +    V        G ++ F K AN  R
Sbjct: 116  SADGIVSTMKKQAGPASVDLRSVEEFEKFVADKDAAVVGFFRDLYSGPHSEFLKAANTLR 175

Query: 577  KDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEF 756
            ++Y F + ++K+++   +   + V +   +P +L  + +        D +KI +  + +F
Sbjct: 176  ENYRFAHTDEKELVDKYDTNGEGVVLF--RPPHLANKFEDGSVTFPAD-EKITSGKIKKF 232

Query: 757  IGVEAVPYFGEINQDTYMTYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKY---RG 918
            I          + QD         L IAYY   +  N +      + + K+ K +     
Sbjct: 233  IQDNIFGLCPHLTQDNKDLIQGKDLLIAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGK 292

Query: 919  KLNIVGLDASLFGRHAEVINMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEK 1092
            KLN    +   FG       +D     +P+  I   +  +KF + +    +G   K +E+
Sbjct: 293  KLNFAVANRKSFGHEVTEFGLDANTGELPVVGI-KTAKGEKFVMQEEFSRDG---KALER 348

Query: 1093 FVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGH 1272
            F+ DYF  KL   +KSE +P   E +  PV   VA N+ +++    KDV +++YAPWCGH
Sbjct: 349  FLQDYFDGKLKRYMKSESIP---ESNDGPVKVAVAENFDELVNDESKDVLIEFYAPWCGH 405

Query: 1273 CKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEK 1452
            CK L P ++EL E    +          +D T NDV   Y + G+PT+   PA  K    
Sbjct: 406  CKTLEPKYKELGEKLADD---PNIVIAKMDATANDVPPQYEVRGFPTIYFAPAGNK---- 458

Query: 1453 TGIREPIVFEGPRELDTLIEFIKEK 1527
               + P  +EG RE+   + ++K++
Sbjct: 459  ---QNPKRYEGGREVSEFLSYLKKE 480



 Score = 74.7 bits (182), Expect = 3e-12
 Identities = 37/119 (31%), Positives = 72/119 (60%), Gaps = 2/119 (1%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFI-EENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           +++ + N   VK+  +ENF   + +E+  +L EF+APWCG+CK L P+Y +  + L +  
Sbjct: 365 ESIPESNDGPVKVAVAENFDELVNDESKDVLIEFYAPWCGHCKTLEPKYKELGEKLADD- 423

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQS 438
           P I +A++D T ++ +  ++ +RG+PT+     G+ +  + Y+G RE +    Y+ K++
Sbjct: 424 PNIVIAKMDATAND-VPPQYEVRGFPTIYFAPAGNKQNPKRYEGGREVSEFLSYLKKEA 481


>Q8IYF8||Q8IYF8 (TrEMBL: Homo sapiens (Human)) Hypothetical protein
            (Fragment).
          Length = 539

 Score =  223 bits (568), Expect = 5e-57
 Identities = 152/485 (31%), Positives = 240/485 (49%), Gaps = 12/485 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT +NF S I +     L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 59   SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LA 115

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 116  KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 173

Query: 460  ETFEELDTLIDAQTKPFVLQINPT-EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKK 636
             T EE    I  +    V   + +  + ++ F K A+  R +Y F +   + ++ + +  
Sbjct: 174  RTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDN 233

Query: 637  FKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTY 816
             + + +   +PS+L    K  D+   +  +K+ +  + +FI          + +D     
Sbjct: 234  GEGIILF--RPSHLT--NKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLI 289

Query: 817  MTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEVIN 978
                L IAYY   +  NA+      + +  + KK+     KLN        F        
Sbjct: 290  QGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFG 349

Query: 979  MDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLP 1152
            ++     +P+ AI   +  +KF + +    +G   K +E+F+ DYF   L   +KSEP+P
Sbjct: 350  LESTAGEIPVVAIR-TAKGEKFVMQEEFSRDG---KALERFLQDYFDGNLKRYLKSEPIP 405

Query: 1153 TEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXX 1332
               E +  PV  +VA N+ +++   +KDV +++YAPWCGHCK L P ++EL E    +  
Sbjct: 406  ---ESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD-- 460

Query: 1333 XXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIE 1512
                    +D T NDV  PY + G+PT+   PAN K++ K        +EG REL   I 
Sbjct: 461  -PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKK-------YEGGRELSDFIS 512

Query: 1513 FIKEK 1527
            +++ +
Sbjct: 513  YLQRE 517



 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 38/126 (30%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFIE-ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   +  EN  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 402 EPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 460

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSL 441
           P I +A++D T ++ +   + +RG+PT+           + Y+G RE +    Y+ +++ 
Sbjct: 461 PNIVIAKMDATAND-VPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREAT 519

Query: 442 --PAVQ 453
             P +Q
Sbjct: 520 NPPVIQ 525


>P30101|GRP58|PDA3_HUMAN (SP: Homo sapiens (Human)) Protein disulfide
            isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase
            ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
            (58 kDa glucose regulated protein).
          Length = 505

 Score =  223 bits (568), Expect = 5e-57
 Identities = 152/485 (31%), Positives = 240/485 (49%), Gaps = 12/485 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEENP---LILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT +NF S I +     L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 25   SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LA 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFP 459
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA    
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQAGPASVPL 139

Query: 460  ETFEELDTLIDAQTKPFVLQINPT-EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKK 636
             T EE    I  +    V   + +  + ++ F K A+  R +Y F +   + ++ + +  
Sbjct: 140  RTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDN 199

Query: 637  FKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTY 816
             + + +   +PS+L    K  D+   +  +K+ +  + +FI          + +D     
Sbjct: 200  GEGIILF--RPSHLT--NKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLI 255

Query: 817  MTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEVIN 978
                L IAYY   +  NA+      + +  + KK+     KLN        F        
Sbjct: 256  QGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFG 315

Query: 979  MDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLP 1152
            ++     +P+ AI   +  +KF + +    +G   K +E+F+ DYF   L   +KSEP+P
Sbjct: 316  LESTAGEIPVVAIR-TAKGEKFVMQEEFSRDG---KALERFLQDYFDGNLKRYLKSEPIP 371

Query: 1153 TEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXX 1332
               E +  PV  +VA N+ +++   +KDV +++YAPWCGHCK L P ++EL E    +  
Sbjct: 372  ---ESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD-- 426

Query: 1333 XXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIE 1512
                    +D T NDV  PY + G+PT+   PAN K++ K        +EG REL   I 
Sbjct: 427  -PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKK-------YEGGRELSDFIS 478

Query: 1513 FIKEK 1527
            +++ +
Sbjct: 479  YLQRE 483



 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 38/126 (30%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFIE-ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   +  EN  +L EF+APWCG+CK L P+Y +  + L++  
Sbjct: 368 EPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSL 441
           P I +A++D T ++ +   + +RG+PT+           + Y+G RE +    Y+ +++ 
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREAT 485

Query: 442 --PAVQ 453
             P +Q
Sbjct: 486 NPPVIQ 491


>Q9TWZ1|PDI|Q9TWZ1 (TrEMBL: Drosophila melanogaster (Fruit fly))
            Protein disulphide isomerase isoform/multifunctional
            endoplasmic reticulum luminal polypeptide (D-ERp60).
          Length = 489

 Score =  221 bits (564), Expect = 2e-56
 Identities = 147/490 (30%), Positives = 242/490 (49%), Gaps = 6/490 (1%)
 Frame = +1

Query: 115  VVKLTSENFASFIEENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCT 294
            V++L  ++FA+ ++++   L  F+APWCG+CK L PEY+KAA+ + +  P IKLA++DCT
Sbjct: 24   VLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCT 83

Query: 295  E-DEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFE 471
            E  +  C ++ + GYPTLKI R    + ++DY GPR+++GIA YM  Q  PA +   T  
Sbjct: 84   EAGKETCSKYSVSGYPTLKIFR--QDEVSQDYNGPRDSSGIAKYMRAQVGPASKTVRTVA 141

Query: 472  ELDTLIDAQTKPFVLQINPTEDGNA-TFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNV 648
            EL   +D +        + ++   A  F K A++ R+ Y F +  +K+++    +  K V
Sbjct: 142  ELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIV 201

Query: 649  DITGKKPSYLVVQPKQFDEVA-KFDGKKIDAESLTEFIGVEAVPYFGEINQDTYMTYMTS 825
             I     S       +F+  + KF+G       L+ F+        G   QD+   +  +
Sbjct: 202  LIRAPHLS------NKFESSSIKFEGS--SESDLSTFVKENFHGLVGHRTQDSVKDFQ-N 252

Query: 826  PLPIAYY---FYNNAEQREAIADDLTKLGKKYRGKLNIVGLDASLFGRHAEVINMDPEVV 996
            PL  AYY   +  N +      + + K+ K++ G++N        F         D    
Sbjct: 253  PLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDFVGD 312

Query: 997  PLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSAN 1176
                +     N K+ +      +  S + ++ FV    A++L P IKSEP+P   E +  
Sbjct: 313  KPVVLARDEKNLKYALK-----DEFSVENLQDFVEKLLANELEPYIKSEPIP---ESNDA 364

Query: 1177 PVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXX 1356
            PV   VA N+ D++    KD  +++YAPWCGHCKKL P +EELA+               
Sbjct: 365  PVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLTPIYEELAQ----KLQDEDVAIVK 420

Query: 1357 IDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEKGAL 1536
            +D T NDV   +N+ G+PTL   P + K        +P+ + G RE+D  +++I ++   
Sbjct: 421  MDATANDVPPEFNVRGFPTLFWLPKDAK-------NKPVSYNGGREVDDFLKYIAKEATT 473

Query: 1537 NVDGAELKAK 1566
             + G +   K
Sbjct: 474  ELKGFDRSGK 483


>P38657|GRP58|PDA3_BOVIN (SP: Bos taurus (Bovine)) Protein disulfide
            isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase
            ER-60) (ERP60) (58 kDa microsomal protein) (P58) (ERp57).
          Length = 505

 Score =  221 bits (563), Expect = 2e-56
 Identities = 152/487 (31%), Positives = 241/487 (49%), Gaps = 14/487 (2%)
 Frame = +1

Query: 109  SAVVKLTSENFASFIEE---NPLILAEFFAPWCGYCKMLGPEYSKAADSLNESHPKIKLA 279
            S V++LT +NF S I +   + L+L EFFAPWCG+CK L PEY  AA  L    P   LA
Sbjct: 25   SDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVP---LA 81

Query: 280  QIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSLPA---V 450
            ++DCT +   C ++G+ GYPTLKI RDG+   A  Y GPR A GI  ++ KQ+ PA   +
Sbjct: 82   KVDCTANTNTCNKYGVSGYPTLKIFRDGEESGA--YDGPRTADGIVSHLKKQAGPASVPL 139

Query: 451  QFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRKDYVFINVEDKQIIKDLN 630
            +  E FE+  +  DA    F   +    + ++ F K A+  R +Y F +   + ++   +
Sbjct: 140  KSEEEFEKFISDKDASVVGFFKDL--FSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYD 197

Query: 631  KKFKNVDITGKKPSYLVVQPKQFDEVAKFDGKKIDAESLTEFIGVEAVPYFGEINQDTYM 810
               + + +   +PS+L    K  D+   +  +K+ +  +  FI          + +D   
Sbjct: 198  DDGEGITLF--RPSHLT--NKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKD 253

Query: 811  TYMTSPLPIAYY---FYNNAEQREAIADDLTKLGKKYRG---KLNIVGLDASLFGRHAEV 972
                  L IAYY   +  NA+      + +  + KK+     KL+        F      
Sbjct: 254  LLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGQKLHFAVASRKTFSHELSD 313

Query: 973  INMDPEV--VPLFAIHHISDNKKFGVNQTDYPEGPSFKVIEKFVADYFADKLTPIIKSEP 1146
              ++     +P+ A+   +  +KF + +    +G   K +E+F+ DYF   L   +KSEP
Sbjct: 314  FGLESTTGEIPVVAVR-TAKGEKFVMQEEFSRDG---KALERFLEDYFDGNLKRYLKSEP 369

Query: 1147 LPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGHCKKLAPTWEELAEIFGSN 1326
            +P   E +  PV  +VA N+ +++   +KDV +++YAPWCGHCK L P ++EL E    +
Sbjct: 370  IP---ESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKD 426

Query: 1327 XXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEKTGIREPIVFEGPRELDTL 1506
                      +D T NDV  PY + G+PT+   PAN K       + P  +EG REL   
Sbjct: 427  ---PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK-------QNPKKYEGGRELSDF 476

Query: 1507 IEFIKEK 1527
            I ++K +
Sbjct: 477  ISYLKRE 483



 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 38/126 (30%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
 Frame = +1

Query: 88  DAVADPNSAVVKLT-SENFASFIE-ENPLILAEFFAPWCGYCKMLGPEYSKAADSLNESH 261
           + + + N   VK+  +ENF   +  EN  +L EF+APWCG+CK L P+Y +  + L +  
Sbjct: 368 EPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKD- 426

Query: 262 PKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPREAAGIADYMIKQSL 441
           P I +A++D T ++ +   + +RG+PT+        +  + Y+G RE +    Y+ +++ 
Sbjct: 427 PNIVIAKMDATAND-VPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREAT 485

Query: 442 --PAVQ 453
             P +Q
Sbjct: 486 NPPVIQ 491


>Q9FE55|PDI|Q9FE55 (TrEMBL: Triticum aestivum (Wheat)) Protein
            disulfide isomerase precursor (EC 5.3.4.1) (Protein
            disulfide isomerase 1 precursor).
          Length = 515

 Score =  219 bits (558), Expect = 8e-56
 Identities = 167/518 (32%), Positives = 251/518 (48%), Gaps = 11/518 (2%)
 Frame = +1

Query: 4    KFWTYSTKVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEF 183
            K W      LA +L+  +          +A A P  AV+ L ++NF   I ++P IL EF
Sbjct: 5    KVWISLLLALAVVLSAPAARAEEAAAAEEAAAAPE-AVLTLHADNFDDAIAKHPFILVEF 63

Query: 184  FAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTED--EALCMEHGIRGYPTLKIIR 357
            +APWCG+CK L PEY KAA  L++  P I LA++D  ++  + L  ++ ++G+PTLKI R
Sbjct: 64   YAPWCGHCKSLAPEYEKAAQLLSKHDPAIVLAKVDANDEKNKPLAGKYEVQGFPTLKIFR 123

Query: 358  DGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTK--PFVLQINPT 531
            +G  K  ++Y+GPREA GI +Y+ KQ  PA +  +  E+   L D +        + + T
Sbjct: 124  NG-GKNIQEYKGPREAEGIVEYLKKQVGPASKEIKAPEDATYLEDGKIHIVGVFTEFSGT 182

Query: 532  EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVA 711
            E  N  F ++A + R DY F +                 D   ++P  LV   K FDE+ 
Sbjct: 183  EFTN--FLELAEKLRSDYDFGHTVHA-------NHLPRGDAAVERP--LVRLFKPFDELV 231

Query: 712  KFDGKKIDAESLTEFIGVEAVPYF-----GEINQDTYMTYMTSPLPIAYYFYN-NAEQRE 873
              D K  D  +L +FI   + P          N    + Y  S  P A  F N +    E
Sbjct: 232  -VDSKDFDVSALEKFIDASSTPKVVTFDKNPDNHPYLLKYFQSNAPKAMLFLNFSTGPFE 290

Query: 874  AIADDLTKLGKKYRGK-LNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ 1050
            +         +++ GK +  +  D        +   +  +  PL  I   SD+KKF   Q
Sbjct: 291  SFKSAYYGAVEEFSGKDVKFLIGDIEASQGAFQYFGLKEDQAPLILIQD-SDSKKFLKEQ 349

Query: 1051 TDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTD 1230
             +  +      I  ++ DYF  KLTP  KSEP+P   E +  PV  +VA N  DV+ ++ 
Sbjct: 350  VEAGQ------IVAWLKDYFDGKLTPFRKSEPIP---EANNEPVKVVVADNIHDVVFKSG 400

Query: 1231 KDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYP 1410
            K+V +++YAPWCGHCKKLAP  +E A    S           ID T NDV   ++++GYP
Sbjct: 401  KNVLIEFYAPWCGHCKKLAPILDEAAATLQSE---EDVVIAKIDATANDVPGEFDVQGYP 457

Query: 1411 TLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKE 1524
            TL     +GK          + +EG R  D ++++IK+
Sbjct: 458  TLYFVTPSGK---------KVSYEGGRTADEIVDYIKK 486


>O76191|NDITG|O76191 (TrEMBL: Dirofilaria immitis (Canine heartworm))
            Transglutaminase precursor.
          Length = 497

 Score =  218 bits (556), Expect = 1e-55
 Identities = 156/518 (30%), Positives = 249/518 (48%), Gaps = 9/518 (1%)
 Frame = +1

Query: 40   LLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEFFAPWCGYCKMLG 219
            L  ++ +T+A    DGD        V+K T  +F   I+   ++L +F+APWCG+CK + 
Sbjct: 16   LFLILPLTNA----DGD--------VMKFTDADFKEGIKPYDVLLVKFYAPWCGHCKKIA 63

Query: 220  PEYSKAADSLNESHPKIKLAQIDCTEDEALCMEHGIRGYPTLKIIRDGDSKTAEDYQGPR 399
            PE+ KAA  L ++ P I LA++DCTE++  C E+G+ G+PTLKI R G+   A+DY GPR
Sbjct: 64   PEFEKAATKLLQNDPPIHLAEVDCTEEKKTCDEYGVSGFPTLKIFRKGE--LAQDYDGPR 121

Query: 400  EAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTKPFVLQINPTEDGNATFNKVANQKRK 579
             A GI  YM  Q+ P+     T +E + ++ A                 +F KVA+ +R 
Sbjct: 122  VAEGIVKYMRGQAGPSATEINTQQEFEKMLQADDVTICGFFEENSKLKDSFLKVADTERD 181

Query: 580  DYVFINVEDKQIIKDLNKKFKNVDITGKKPS--YLVVQPKQFDEVAKFDGKKIDAESLTE 753
             + F+   +KQI   L  +  N DI   +P   +   +P +F    K+DG   D + + E
Sbjct: 182  RFKFVWTSNKQI---LESRGYNDDIVAYQPKKFHNKFEPNEF----KYDG-NYDTDKIKE 233

Query: 754  FIGVEAVPYFGEINQDTYMTYMTSPLPIAY---YFYNNAEQREAIADDLTKLGKKYRGKL 924
            F+  E     G    +    Y   P+ + Y    +  + +      + +  + K Y+ K 
Sbjct: 234  FLLHETNGLVGIRTAENRYQYDLLPMFVVYGKVDYELDPKGSNYWRNRVLMVAKDYKRKA 293

Query: 925  NIVGLDASLFGRHAEVINM--DPEVVPLFAIHHISDNKKFGVNQTDYPEGPSFKV--IEK 1092
            N    +   F    +   +    +  PL A    S   KF +      E  SF V  ++K
Sbjct: 294  NFAMSNKEDFSFDLDEFGLANRKDTKPLVAAR--SKKGKFFMK-----EEFSFSVENLKK 346

Query: 1093 FVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTDKDVFVKYYAPWCGH 1272
            FV D   D+L P +KSE  P ++      V  +VA  +++++   +KDV +++YAPWCGH
Sbjct: 347  FVEDVIGDRLEPYMKSEEAPEDQ----GDVKVVVAKTFQEMIMNVEKDVLIEFYAPWCGH 402

Query: 1273 CKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYPTLLMFPANGKVDEK 1452
            CK LAP ++EL +               +D T NDV  P+ ++G+PTL   P N K    
Sbjct: 403  CKALAPKYDELGQKLSGE---PGVVIAKMDATANDVPPPFQVQGFPTLYWVPKNKK---- 455

Query: 1453 TGIREPIVFEGPRELDTLIEFIKEKGALNVDGAELKAK 1566
                +P  + G RE+D  I++I +     + G +   K
Sbjct: 456  ---DKPEPYSGGREVDDFIKYIAKHATEELKGYKRDGK 490


>Q93XQ7|PDI3|Q93XQ7 (TrEMBL: Triticum aestivum (Wheat)) Protein
            disulfide isomerase 3 precursor (EC 5.3.4.1).
          Length = 515

 Score =  218 bits (554), Expect = 2e-55
 Identities = 170/538 (31%), Positives = 258/538 (47%), Gaps = 11/538 (2%)
 Frame = +1

Query: 4    KFWTYSTKVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEF 183
            K W      LA +L+  +          +  A P  AV+ L ++NF   I ++P IL EF
Sbjct: 5    KAWISLLLALAVVLSAPAARAEEAAAAAEEAAAPE-AVLTLHADNFDDAIAKHPFILVEF 63

Query: 184  FAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTED--EALCMEHGIRGYPTLKIIR 357
            +APWCG+CK L PEY KAA  L++  P I LA++D  ++  + L  ++ ++G+PTLKI R
Sbjct: 64   YAPWCGHCKSLAPEYEKAAQLLSKHDPAIVLAKVDANDEKNKPLAGKYEVQGFPTLKIFR 123

Query: 358  DGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTK--PFVLQINPT 531
            +G  K  ++Y+GPREA GI +Y+ KQ  PA +  +  E+   L D +        + + T
Sbjct: 124  NG-GKNIQEYKGPREAEGIVEYLKKQVGPASKEIKAPEDATYLEDGKIHIVGVFTEFSGT 182

Query: 532  EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVA 711
            E  N  F +VA + R DY F +                 D   ++P  LV   K FDE+ 
Sbjct: 183  EFTN--FLEVAEKLRSDYDFGHTVHA-------NHLPRGDAAVERP--LVRLFKPFDELV 231

Query: 712  KFDGKKIDAESLTEFIGVEAVPYF-----GEINQDTYMTYMTSPLPIAYYFYN-NAEQRE 873
              D K  D  +L +FI   + P          N    + +  +  P A  F N +    E
Sbjct: 232  -VDSKDFDVSALEKFIDASSTPKVVTFDKNPDNHPYLLKFFQTNAPKAMLFLNFSTGPFE 290

Query: 874  AIADDLTKLGKKYRGK-LNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ 1050
            +         +++ GK +  +  D        +   +  +  PL  I   SD+KKF   Q
Sbjct: 291  SFKSAYYGAVEEFSGKDVKFLIGDIEASQGAFQYFGLKEDQAPLILIQD-SDSKKFLKEQ 349

Query: 1051 TDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTD 1230
             +  +      I  ++ DYF  KLTP  KSEP+P   E +  PV  +VA N  DV+ ++ 
Sbjct: 350  VEAGQ------IVAWLKDYFDGKLTPFRKSEPIP---EANNEPVKVVVADNVHDVVFKSG 400

Query: 1231 KDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYP 1410
            K+V +++YAPWCGHCKKLAP  +E A    S           +D T NDV   ++++GYP
Sbjct: 401  KNVLIEFYAPWCGHCKKLAPILDEAAATLQSE---EDVVIAKMDATANDVPSEFDVQGYP 457

Query: 1411 TLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKEKGALNVDGAELKAKLDEQKA 1584
            TL     +GK          + +EG R  D ++++IK+    N + A   A  D +KA
Sbjct: 458  TLYFVTPSGK---------KVSYEGGRTADEIVDYIKK----NKETAGQAAAADTEKA 502


>Q93XQ8|PDI2|Q93XQ8 (TrEMBL: Triticum aestivum (Wheat)) Protein
            disulfide isomerase 2 precursor (EC 5.3.4.1).
          Length = 512

 Score =  217 bits (553), Expect = 3e-55
 Identities = 166/518 (32%), Positives = 251/518 (48%), Gaps = 11/518 (2%)
 Frame = +1

Query: 4    KFWTYSTKVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEF 183
            K W      LA +L+  +          +A A P  AV+ L ++NF   I ++P IL EF
Sbjct: 5    KVWISLLLALAVVLSAPAARAEEAAAAEEAAAAPE-AVLTLHADNFDDAIAKHPFILVEF 63

Query: 184  FAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTED--EALCMEHGIRGYPTLKIIR 357
            +APWCG+CK L PEY KAA  L++  P I LA++D  ++  + L  ++ ++G+PTLKI R
Sbjct: 64   YAPWCGHCKSLAPEYEKAAQLLSKHDPAIVLAKVDANDEKNKPLAGKYEVQGFPTLKIFR 123

Query: 358  DGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTK--PFVLQINPT 531
            +G  K  ++Y+GPREA GI +Y+ KQ  PA +  +  E+   L D +        + + T
Sbjct: 124  NG-GKNIQEYKGPREAEGIVEYLKKQVGPASKEIKAPEDATYLEDGKIHIVGVFTEFSGT 182

Query: 532  EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVA 711
            E  N  F +VA + R DY F +                 D   ++P  LV   K FDE+ 
Sbjct: 183  EFTN--FLEVAEKLRSDYDFGHTVHA-------NHLPRGDAAVERP--LVRLFKPFDELV 231

Query: 712  KFDGKKIDAESLTEFIGVEAVPYF-----GEINQDTYMTYMTSPLPIAYYFYN-NAEQRE 873
              D K  D  +L +FI   + P          N    + +  S  P A  F N +    E
Sbjct: 232  -VDSKDFDVSALEKFIEASSTPKVVTFDKNPDNHPYLLKFFQSNAPKAMLFLNFSTGPFE 290

Query: 874  AIADDLTKLGKKYRGK-LNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ 1050
            +         +++ GK +  +  D        +   +  +  PL  I   SD+KKF   Q
Sbjct: 291  SFKKAYYGAVEEFSGKDVKFLIGDIEASQGAFQYFGLKEDQAPLILIQD-SDSKKFLKEQ 349

Query: 1051 TDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTD 1230
             +  +      I  ++ DYF  KLTP  KSEP+P   E +  PV  +VA N  DV+ ++ 
Sbjct: 350  VEAGQ------IVAWLKDYFDGKLTPFRKSEPIP---EANNEPVKVVVADNVHDVVFKSG 400

Query: 1231 KDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYP 1410
            K+V +++YAPWCGHCKKLAP  +E A    S           +D T NDV   ++++GYP
Sbjct: 401  KNVLIEFYAPWCGHCKKLAPILDEAAATLQSE---EDVVIAKMDATANDVPSEFDVQGYP 457

Query: 1411 TLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKE 1524
            TL     +GK          + +EG R  D ++++IK+
Sbjct: 458  TLYFVTPSGK---------KVSYEGGRTADEIVDYIKK 486


>P52589|PDI|PDI_WHEAT (SP: Triticum aestivum (Wheat)) Protein
            disulfide isomerase precursor (PDI) (EC 5.3.4.1).
          Length = 515

 Score =  217 bits (553), Expect = 3e-55
 Identities = 167/518 (32%), Positives = 250/518 (48%), Gaps = 11/518 (2%)
 Frame = +1

Query: 4    KFWTYSTKVLATLLAVVSITHASGPTDGDAVADPNSAVVKLTSENFASFIEENPLILAEF 183
            K W      LA +L+  +          +A A P  AV+ L ++NF   I ++P IL EF
Sbjct: 5    KVWISLLLALAVVLSAPAARAEEAAAAEEAAAAPE-AVLTLHADNFDDAIAKHPFILVEF 63

Query: 184  FAPWCGYCKMLGPEYSKAADSLNESHPKIKLAQIDCTED--EALCMEHGIRGYPTLKIIR 357
            +APWCG+CK L PEY KAA  L++  P I LA++D  ++  + L  ++ ++G+PTLKI R
Sbjct: 64   YAPWCGHCKSLAPEYEKAAQLLSKHDPAIVLAKVDANDEKNKPLAGKYEVQGFPTLKIFR 123

Query: 358  DGDSKTAEDYQGPREAAGIADYMIKQSLPAVQFPETFEELDTLIDAQTK--PFVLQINPT 531
             G  K  ++Y+GPREA GI +Y+ KQ  PA +  +  E+   L D +        + + T
Sbjct: 124  SG-GKNIQEYKGPREAEGIVEYLKKQVGPASKEIKAPEDATYLEDGKIHIVGVFTEFSGT 182

Query: 532  EDGNATFNKVANQKRKDYVFINVEDKQIIKDLNKKFKNVDITGKKPSYLVVQPKQFDEVA 711
            E  N  F ++A + R DY F +                 D   ++P  LV   K FDE+ 
Sbjct: 183  EFTN--FLELAEKLRSDYDFGHTVHA-------NHLPRGDAAVERP--LVRLFKPFDELV 231

Query: 712  KFDGKKIDAESLTEFIGVEAVPYF-----GEINQDTYMTYMTSPLPIAYYFYN-NAEQRE 873
              D K  D  +L +FI   + P          N    + Y  S  P A  F N +    E
Sbjct: 232  -VDSKDFDVSALEKFIDASSTPKVVTFDKNPDNHPYLLKYFQSNAPKAMLFLNFSTGPFE 290

Query: 874  AIADDLTKLGKKYRGK-LNIVGLDASLFGRHAEVINMDPEVVPLFAIHHISDNKKFGVNQ 1050
            +         +++ GK +  +  D        +   +  +  PL  I   SD+KKF   Q
Sbjct: 291  SFKSAYYGAVEEFSGKDVKFLIGDIEASQGAFQYNGLKEDQAPLILIQD-SDSKKFLKEQ 349

Query: 1051 TDYPEGPSFKVIEKFVADYFADKLTPIIKSEPLPTEEEKSANPVVKLVAHNYKDVLEQTD 1230
             +  +      I  ++ DYF  KLTP  KSEP+P   E +  PV  +VA N  DV+ ++ 
Sbjct: 350  VEAGQ------IVAWLKDYFDGKLTPFRKSEPIP---EANNEPVKVVVADNIHDVVFKSA 400

Query: 1231 KDVFVKYYAPWCGHCKKLAPTWEELAEIFGSNXXXXXXXXXXIDHTNNDVDVPYNIEGYP 1410
            K+V +++YAPWCGHCKKLAP  +E A    S           ID T NDV   ++++GYP
Sbjct: 401  KNVLIEFYAPWCGHCKKLAPILDEAAATLQSE---EDVVIAKIDATANDVPGEFDVQGYP 457

Query: 1411 TLLMFPANGKVDEKTGIREPIVFEGPRELDTLIEFIKE 1524
            TL     +GK          + +EG R  D ++++IK+
Sbjct: 458  TLYFVTPSGK---------KVSYEGGRTADEIVDYIKK 486


  Database: sptrembl
    Posted date:  Oct 14, 2003  6:47 PM
  Number of letters in database: 339,323,595
  Number of sequences in database:  1,070,300
  
Lambda     K      H
   0.316    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 445,422,798
Number of Sequences: 1070300
Number of extensions: 9318425
Number of successful extensions: 34963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31565
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33768
length of database: 339,323,595
effective HSP length: 127
effective length of database: 203,395,495
effective search space used: 87866853840
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)